The New England journal of medicine, 2023-06, Vol.388 (24), p.2241-2252
- Baghdassarian, Hratch
- Blackstone, Sarah A.
- Clay, Owen S.
- Philips, Rachael
- Matthiasardottir, Brynja
- Nehrebecky, Michele
- Hua, Vivian K.
- McVicar, Rachael
- Liu, Yang
- Tucker, Suzanne M.
- Randazzo, Davide
- Deuitch, Natalie
- Rosenzweig, Sofia
- Mark, Adam
- Sasik, Roman
- Fisch, Kathleen M.
- Pimpale Chavan, Pallavi
- Eren, Elif
- Watts, Norman R.
- Ma, Chi A.
- Gadina, Massimo
- Schwartz, Daniella M.
- Sanyal, Anwesha
- Werner, Giffin
- Murdock, David R.
- Horita, Nobuyuki
- Chowdhury, Shimul
- Dimmock, David
- Jepsen, Kristen
- Remmers, Elaine F.
- Goldbach-Mansky, Raphaela
- Gahl, William A.
- O’Shea, John J.
- Milner, Joshua D.
- Lewis, Nathan E.
- Chang, Johanna
- Kastner, Daniel L.
- Torok, Kathryn
- Oda, Hirotsugu
- Putnam, Christopher D.
- Broderick, Lori
2023
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Baghdassarian, Hratch
- Blackstone, Sarah A.
- Clay, Owen S.
- Philips, Rachael
- Matthiasardottir, Brynja
- Nehrebecky, Michele
- Hua, Vivian K.
- McVicar, Rachael
- Liu, Yang
- Tucker, Suzanne M.
- Randazzo, Davide
- Deuitch, Natalie
- Rosenzweig, Sofia
- Mark, Adam
- Sasik, Roman
- Fisch, Kathleen M.
- Pimpale Chavan, Pallavi
- Eren, Elif
- Watts, Norman R.
- Ma, Chi A.
- Gadina, Massimo
- Schwartz, Daniella M.
- Sanyal, Anwesha
- Werner, Giffin
- Murdock, David R.
- Horita, Nobuyuki
- Chowdhury, Shimul
- Dimmock, David
- Jepsen, Kristen
- Remmers, Elaine F.
- Goldbach-Mansky, Raphaela
- Gahl, William A.
- O’Shea, John J.
- Milner, Joshua D.
- Lewis, Nathan E.
- Chang, Johanna
- Kastner, Daniel L.
- Torok, Kathryn
- Oda, Hirotsugu
- Putnam, Christopher D.
- Broderick, Lori
- Titel
- Variant STAT4 and Response to Ruxolitinib in an Autoinflammatory Syndrome
- Ist Teil von
- The New England journal of medicine, 2023-06, Vol.388 (24), p.2241-2252
- Ort / Verlag
- United States: Massachusetts Medical Society
- Erscheinungsjahr
- 2023
- Quelle
- Free E-Journal (出版社公開部分のみ）
- Beschreibungen/Notizen
- Genetic analyses of three families with disabling pansclerotic morphea uncovered a cause of the disease, providing insight into the molecular pathology of the disease and leading to an experimental, targeted treatment.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0028-4793eISSN: 1533-4406DOI: 10.1056/NEJMoa2202318Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10392571
- Format
- –
- Schlagworte
- Age, Allergy, Anti-Inflammatory Agents - therapeutic use, Asthma, Autoimmune Diseases - drug therapy, Autoimmune Diseases - genetics, Biopsy, Cytokines, Dermatologic Agents - therapeutic use, Dermatology, Dermatology General, Disease, Fibroblasts, Fibrosis, Gain of Function Mutation, Gene expression, Genes, Genetics, Genetics General, Genomics, Hematology, Hypogammaglobulinemia, Immunology, Inflammatory Disease, Inflammatory diseases, Inhibitor drugs, Interferon, Interleukin 6, Janus kinase, Janus Kinases - antagonists & inhibitors, Kinases, Leukocytes (mononuclear), Mutation, Missense, Nitriles, Oncology, Oncology General, Peripheral blood, Phenotypes, Plasmids, Proteins, Pyrazoles - pharmacology, Pyrazoles - therapeutic use, Pyrimidines, Scleroderma, Scleroderma, Systemic - drug therapy, Scleroderma, Systemic - genetics, Software, Squamous cell carcinoma, Stat4 protein, T-Cells, Wound healing