Details

Autor(en) / Beteiligte

• Pang, Haowen
• Wu, Kui
• Shi, Xiangxiang
• Tang, Tao
• Sun, Xiaoyang
• Yang, Bo
• Wu, Jingbo
• Lin, Sheng

Titel

Hypofractionated 192 Ir source stereotactic ablative brachytherapy with coplanar template assistance in the primary treatment of peripheral lung cancer

Ist Teil von

• Journal of contemporary brachytherapy, 2019-08, Vol.11 (4), p.370

Ort / Verlag

Poland

Erscheinungsjahr

2019

Link zum Volltext

Quelle

EZB Free E-Journals

Beschreibungen/Notizen

• In this study, we reported the safety and efficacy of hypofractionated Ir source stereotactic ablative brachytherapy (SABT) with coplanar template assistance for peripheral lung cancer, and compared the dosimetric parameters between SABT and stereotactic body radiotherapy (SBRT). Thirty-three peripheral lung cancer patients, with the gross lung tumor volume (GTVL) < 5 cm in diameter were enrolled in this study. We assessed the safety and efficacy of SABT, and compared the dosimetric parameters between SABT and SBRT. Chest computed tomography (CT) of post-SABT revealed mild pneumothorax in 2 of 33 patients. Complete response (CR) plus partial response (PR) rate for GTVL at 6-month was 100%. Local control (LC) rate for GTVL at 1-year was 96.9%. For organs at risk (OARs), D1000 cm , and D1500 cm for lung in 1, 3, and 5 fractions were not statistically different between SABT and SBRT (all > 0.05); the remaining dosimetric parameters were significantly lower in SABT than in SBRT (all < 0.01). SABT can provide safe and effective treatment, and warrant generalization for peripheral lung cancer.