Details

Autor(en) / Beteiligte

• Hubert, Grace
• Chung, Theresa Tam
• Prosser, Connie
• Lien, Dale
• Weinkauf, Justin
• Brown, Neil
• Goodvin, Marianne
• Jackson, Kathy
• Tabak, Joan
• Salgado, Josette
• Alzaben, Abeer Salman
• Mager, Diana R

Titel

Bone Mineral Density and Fat-Soluble Vitamin Status in Adults with Cystic Fibrosis Undergoing Lung Transplantation: A Pilot Study

Ist Teil von

• Canadian journal of dietetic practice and research, 2016-12, Vol.77 (4), p.199

Ort / Verlag

Canada

Erscheinungsjahr

2016

Quelle

MEDLINE

Beschreibungen/Notizen

• Patients with cystic fibrosis (CF) often experience low bone mineral density (BMD) pre- and post-lung transplantation (LTX). The study purpose was to describe BMD and micronutrient status in adults with CF pre- and post-LTX. Twelve patients with CF (29 ± 8 years) were recruited from the CF clinic at the University of Alberta Lung Transplant Program. BMD and vitamins A, D, E, K status, and parathyroid hormone were measured pre- and post-LTX. No significant differences pre- and post-LTX were observed at the different bone sites measured (lumber-spine, femoral-neck (FN), hip, and femoral-trochlea) (P > 0.05). BMD T-scores (<-2) was present in lumbar-spine, FN, hip, and femoral-trochlea in 33%, 17%, 17%, and 25% of individuals pre-LTX and 58%, 33%, 58%, and 33% of individuals post-LTX, respectively. More than 50% of patients had suboptimal vitamin K levels (PIVKA-II values >3 ng/mL) pre- and post-LTX. Adults with CF pre- and post-LTX had reduced BMD and suboptimal vitamin K status.