Details

Autor(en) / Beteiligte

• Kerr, Gillian
• Ray, Gautamananda
• Wu, Olivia
• Stott, David J.
• Langhorne, Peter

Titel

Elevated Troponin after Stroke: A Systematic Review

Ist Teil von

• Cerebrovascular diseases (Basel, Switzerland), 2009-01, Vol.28 (3), p.220-226

Ort / Verlag

Basel, Switzerland: S. Karger AG

Erscheinungsjahr

2009

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Background: Troponin levels are elevated in some acute stroke patients, but the clinical significance of this is unclear. Methods: We conducted a systematic review of studies measuring troponin within 7 days of symptom onset in acute stroke patients. Results: We identified 15 studies (2,901 patients). Overall 18.1% (95% CI 13.6–22.6) had a positive troponin level. These patients were more likely to have electrocardiogram (ECG) changes suggestive of myocardial ischemia (OR 3.0; 95% CI 1.5–6.2), and there was an independent association with death (OR 2.9; 95% CI 1.7–4.8). Conclusion: Elevated troponin level after acute stroke is common and is associated with ECG changes suggestive of myocardial ischemia and increased risk of death.