Details

Autor(en) / Beteiligte

• Liu, Yi
• Ma, Yu-hua
• Yang, Jian-wei
• Man, Jiang-wei
• Wang, Hua-bin
• Li, Yi
• Liang, Cheng
• Cao, Jin-long
• Chen, Si-yu
• Li, Kun-peng
• Yang, Li

Titel

Rethinking neutrophil extracellular traps

Ist Teil von

• International immunopharmacology, 2023-11, Vol.124, p.110834-110834, Article 110834

Ort / Verlag

Elsevier B.V

Erscheinungsjahr

2023

Link zum Volltext

Quelle

Elsevier ScienceDirect Journals Complete

Beschreibungen/Notizen

• •Discusses several different pathways for NETs formation.•Examine the antimicrobial properties of NETs.•Discusses the relationship between NETs and fibrosis.•Discusses the physiological clearance of NETs and related pharmacological interventions. Neutrophils are a major subset of leukocytes in human circulating blood. In some circumstances, neutrophils release neutrophil extracellular traps (NETs). lnitially, NETs were considered to have a strong antibacterial capacity. However, currently, NETs have been shown to have a pivotal impact on various diseases. Different stimulators induce the production of different types of NETs, and their biological functions and modes of clearance do not appear to be the same. In this review, we will discuss several important issues related to NETs in order to better understand the relationship between NETs and diseases, as well as how to utilize the characteristics of NETs for disease treatment.