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Risk factors for dementia accumulate during life, but the effect of concomitant diseases on cognitive decline across the lifespan is still undefined. A new study has shown that focal epilepsy is associated with a considerable risk of developing dementia, but that this effect is magnified by modifiable cardiovascular risk factors.A new study using the UK Biobank database has shown that people with epilepsy are at an increased risk of developing dementia. The results demonstrate that this risk is multiplied in individuals who also have high cardiovascular risk, highlighting the importance of addressing modifiable cardiovascular risk factors.