Details

Autor(en) / Beteiligte

• Kusuda, Satoshi
• Nakanishi, Hidehiko
• Suzuki, Hideaki

Titel

Validation of eligibility criteria for the Japan Obstetric Compensation System for Cerebral Palsy in preterm infants: A case–control cohort study

Ist Teil von

• The journal of obstetrics and gynaecology research, 2023-01, Vol.49 (1), p.220-231

Ort / Verlag

Kyoto, Japan: John Wiley & Sons Australia, Ltd

Erscheinungsjahr

2023

Link zum Volltext

Quelle

Wiley Online Library All Journals

Beschreibungen/Notizen

• Aim To verify validity of the criteria used for the Japan Obstetric Compensation System for Cerebral Palsy (JOCS‐CP) in preterm infants, the association between the criteria and the development of CP was studied using a neonatal database. Our hypothesis was that the criteria would not be sufficient due to the recent advances made in perinatal care. Methods Preterm infants born between 2003 and 2019 and registered in the Neonatal Research Network of Japan database with a birth weight of 1500 g or less or a gestational age of less than 32 weeks were analyzed. The database included the clinical information of registered infants during their stay in NICUs and outcomes at 3 years of age. Results The database included 73 615 infants. After excluding those with an unknown outcome at discharge, 73 464 infants were analyzed for short‐term outcomes, including mortality and morbidities. The incidence of CP at 3 years of age was analyzed in 36 151 infants. Furthermore, 16 467 infants born between 28 and 31 weeks of gestation were examined in terms of the validity of the current eligibility criteria. The mortality and incidences of severe intraventricular hemorrhage and periventricular leukomalacia significantly decreased during the study period (Cochrane–Armitage test, p < 0.01). Furthermore, the eligibility criteria were not sufficiently nor strongly associated with indicators for detecting perinatal hypoxia‐ischemia resulting in CP. Conclusion The existing eligibility criteria of the JOCS‐CP used for preterm infants born between 28 and 31 weeks were no longer suitable because of the advances in perinatal care in Japan.