Details

Autor(en) / Beteiligte

• Ridder, B
• Mattes, D S
• Nesterov-Mueller, A
• Breitling, F
• Meier, M A R

Titel

Peptide array functionalization via the Ugi four-component reaction

Ist Teil von

• Chemical communications (Cambridge, England), 2017-05, Vol.53 (40), p.5553-5556

Ort / Verlag

England

Erscheinungsjahr

2017

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• The Ugi four-component reaction was investigated as a tool for the functionalization of peptide arrays via post-synthetic side-chain modification, mimicking post-translational processes. Additionally, as a proof of concept for the synthesis of peptidomimetics on arrays, the integration of an Ugi unit into a growing peptide chain was demonstrated.