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  • BibTeX
Gallic acid isolated from Spirogyra sp. improves cardiovascular disease through a vasorelaxant and antihypertensive effect
Environmental toxicology and pharmacology, 2015-03, Vol.39 (2), p.764-772
2015

Details

Autor(en) / Beteiligte
Titel
Gallic acid isolated from Spirogyra sp. improves cardiovascular disease through a vasorelaxant and antihypertensive effect
Ist Teil von
  • Environmental toxicology and pharmacology, 2015-03, Vol.39 (2), p.764-772
Ort / Verlag
Netherlands: Elsevier B.V
Erscheinungsjahr
2015
Link zum Volltext
Quelle
MEDLINE
Beschreibungen/Notizen
  • Highlights • GA, a strong antioxidant isolated from Spirogyra sp., possesses vasorelaxant effect in HUVECs. • GA inhibits angiotensin I converting enzyme (ACE) and administration of GA reduces the blood pressure in SHRs. • GA exerts multiple therapeutic effects on CVDs related to vasorelaxant and antihypertensive effect.
Sprache
Englisch
Identifikatoren
ISSN: 1382-6689
eISSN: 1872-7077
DOI: 10.1016/j.etap.2015.02.006
Titel-ID: cdi_proquest_miscellaneous_1732821450
Format
–
Schlagworte
Angiotensin-Converting Enzyme Inhibitors - isolation & purification, Angiotensin-Converting Enzyme Inhibitors - pharmacology, Angiotensin-Converting Enzyme Inhibitors - therapeutic use, Animals, Antihypertensive Agents - isolation & purification, Antihypertensive Agents - pharmacology, Antihypertensive Agents - therapeutic use, Antihypertensive effect, Antioxidants - isolation & purification, Antioxidants - pharmacology, Antioxidants - therapeutic use, Cardiovascular diseases, Cardiovascular Diseases - drug therapy, Cardiovascular Diseases - physiopathology, Cells, Cultured, Cyclic Nucleotide Phosphodiesterases, Type 3 - metabolism, Emergency, Gallic acid, Gallic Acid - isolation & purification, Gallic Acid - pharmacology, Gallic Acid - therapeutic use, Human Umbilical Vein Endothelial Cells - drug effects, Human Umbilical Vein Endothelial Cells - metabolism, Humans, Male, Nitric Oxide - metabolism, Nitric Oxide Synthase Type III - metabolism, Rats, Rats, Inbred SHR, Spirogyra, Spirogyra - chemistry, Spyrogira sp, Vasodilator Agents - isolation & purification, Vasodilator Agents - pharmacology, Vasodilator Agents - therapeutic use, Vasorelaxation

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