Details

Autor(en) / Beteiligte

• Liu, Junjun
• Yu, Fang
• Sun, Yao
• Jiang, Beizhan
• Zhang, Wenjun
• Yang, Jianhua
• Xu, Guo‐Tong
• Liang, Aibin
• Liu, Shangfeng

Titel

Concise Reviews: Characteristics and Potential Applications of Human Dental Tissue‐Derived Mesenchymal Stem Cells

Ist Teil von

• Stem cells (Dayton, Ohio), 2015-03, Vol.33 (3), p.627-638

Ort / Verlag

United States: Wiley Subscription Services, Inc

Erscheinungsjahr

2015

Link zum Volltext

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• Recently, numerous types of human dental tissue‐derived mesenchymal stem cells (MSCs) have been isolated and characterized, including dental pulp stem cells, stem cells from exfoliated deciduous teeth, periodontal ligament stem cells, dental follicle progenitor cells, alveolar bone‐derived MSCs, stem cells from apical papilla, tooth germ progenitor cells, and gingival MSCs. All these MSC‐like cells exhibit self‐renewal, multilineage differentiation potential, and immunomodulatory properties. Several studies have demonstrated the potential advantages of dental stem cell‐based approaches for regenerative treatments and immunotherapies. This review outlines the properties of various dental MSC‐like populations and the progress toward their use in regenerative therapy. Several dental stem cell banks worldwide are also introduced, with a view toward future clinical application. Stem Cells 2015;33:627–638