Details

Autor(en) / Beteiligte

• Liu, Jing
• Sun, Yuan-Qiang
• Huo, Yingying
• Zhang, Hongxing
• Wang, Linfang
• Zhang, Pei
• Song, Dan
• Shi, Yawei
• Guo, Wei

Titel

Simultaneous Fluorescence Sensing of Cys and GSH from Different Emission Channels

Ist Teil von

• Journal of the American Chemical Society, 2014-01, Vol.136 (2), p.574-577

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2014

Quelle

MEDLINE

Beschreibungen/Notizen

• A chlorinated coumarin-hemicyanine dye with three potential reaction sites was exploited as fluorescent probe for biothiols. The Cys-induced substitution–rearrangement–cyclization, Hcy-induced substitution–rearrangement, and GSH-induced substitution–cyclizatioin cascades lead to the corresponding amino-coumarin, amino-coumarin-hemicyanine, thiol-coumarin with distinct photophysical properties, enabling Cys and GSH to be selectively detected from different emission channels at two different excitation wavelengths.