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Gene therapy clinical trials worldwide to 2012 - an update
The journal of gene medicine, 2013-02, Vol.15 (2), p.65-77
Ginn, Samantha L.
Alexander, Ian E.
Edelstein, Michael L.
Abedi, Mohammad R.
Wixon, Jo
2013
Details
Autor(en) / Beteiligte
Ginn, Samantha L.
Alexander, Ian E.
Edelstein, Michael L.
Abedi, Mohammad R.
Wixon, Jo
Titel
Gene therapy clinical trials worldwide to 2012 - an update
Ist Teil von
The journal of gene medicine, 2013-02, Vol.15 (2), p.65-77
Ort / Verlag
England: Blackwell Publishing Ltd
Erscheinungsjahr
2013
Link zum Volltext
Quelle
Wiley Online Library Journals Frontfile Complete
Beschreibungen/Notizen
To date, over 1800 gene therapy clinical trials have been completed, are ongoing or have been approved worldwide. Our database brings together global information on gene therapy clinical trials from official agency sources, published literature, conference presentations and posters kindly provided to us by individual investigators or trial sponsors. This review presents our analysis of clinical trials that, to the best of our knowledge, have been or are being performed worldwide. As of our June 2012 update, we have entries on 1843 trials undertaken in 31 countries. We have analysed the geographical distribution of trials, the disease indications (or other reasons) for trials, the proportions to which different vector types are used, and which genes have been transferred. Details of the analyses presented, and our searchable database are available on The Journal of Gene Medicine Gene Therapy Clinical Trials Worldwide website at: http://www.wiley.co.uk/genmed/clinical. We also provide an overview of the progress being made in clinical trials of gene therapy approaches around the world and discuss the prospects for the future. Copyright © 2013 John Wiley & Sons, Ltd.
Sprache
Englisch
Identifikatoren
ISSN: 1099-498X
eISSN: 1521-2254
DOI: 10.1002/jgm.2698
Titel-ID: cdi_proquest_miscellaneous_1313417478
Format
–
Schlagworte
Animals
,
Cardiovascular Diseases - therapy
,
clinical trials
,
Clinical Trials as Topic
,
Disease Models, Animal
,
Gene therapy
,
Gene Transfer Techniques
,
Genetic Therapy - methods
,
Genetic Therapy - trends
,
Genetic Vectors
,
Humans
,
Neoplasms - therapy
,
The Journal of Gene Medicine
,
Viruses - genetics
,
worldwide
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