Details

Autor(en) / Beteiligte

• Berden, Annelies
• Göçeroglu, Arda
• Jayne, David
• Luqmani, Raashid
• Rasmussen, Niels
• Bruijn, Jan Anthonie
• Bajema, Ingeborg

Titel

Diagnosis and management of ANCA associated vasculitis

Ist Teil von

• BMJ, 2012-01, Vol.344 (jan16 2), p.e26-e26

Auflage

International edition

Ort / Verlag

England: BMJ Publishing Group

Erscheinungsjahr

2012

Quelle

Applied Social Sciences Index & Abstracts (ASSIA)

Beschreibungen/Notizen

• Vasculitides associated with antineutrophil cytoplasmic antibodies (ANCAs) are systemic autoimmune diseases of unknown cause that affect small to medium sized blood vessels. They include granulomatosis with polyangiitis, microscopic polyangiitis, and eosinophilic granulomatosis with polyangiitis. Early diagnosis and treatment may prevent progression to end organ damage and lengthen healthier life. A recent large survey of patients with ANCA associated vasculitis found a lag of 3 to 12 months between disease onset and diagnosis, suggesting that diagnostic delay is a problem. Here, Berden et al review the diagnosis and management of ANCA associated vasculitides for the generalist reader, drawing on the findings of observational studies, randomized controlled trials, and meta-analyses.