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A turn-on fluorescent Zn() metal-organic framework sensor for quantitative anthrax biomarker detection
Ist Teil von
Dalton transactions : an international journal of inorganic chemistry, 2023-05, Vol.52 (18), p.667-676
Ort / Verlag
England: Royal Society of Chemistry
Erscheinungsjahr
2023
Link zum Volltext
Quelle
Alma/SFX Local Collection
Beschreibungen/Notizen
2,6-Pyridine dicarboxylic acid (DPA) is considered one of the main anthrax biomarkers, and the detection of DPA is of great significance. This work presents a Zn(
ii
)-based metal-organic framework (MOF) with the formula {[Zn
2
(2,6-NBC)
2
(vlpy)Zn(2,6-NBC)(vlpy)
0.5
]·0.8(2,6-H
2
NBC)·H
2
O}
n
(
1
) assembled from 2,6-naphthalenedicarboxylic acid (2,6-H
2
NBC) and 4,4′-vinylenedipyridine (vlpy) for a photoluminescence sensor matrix for DPA detection.
1
features a 3D pillar-layer framework with nanopore sizes of
ca.
13.165 Å × 12.731 Å, 12.725 Å × 11.018 Å and 13.114 Å × 13.165 Å along the three directions, occupied by lattice water and disordered 2,6-H
2
NBC molecules. The obtained
1
can be used as a turn-on fluorescence sensor for the detection of DPA with high selectivity, excellent sensitivity and recyclability. The luminescence of
1
demonstrates an obvious color change from blue to purplish blue as the DPA concentration rises. Furthermore, a linear correlation is presented between the fluorescence and a low DPA concentration of 0-0.3 mM, and the detection limit can reach as low as 128 nM, much lower than that of an infectious dose to a human of anthrax spores (60 μM). A fluorescence test paper is fabricated to detect DPA rapidly through color change. DFT calculations indicate the intermolecular photoinduced electron-transfer transition and hydrogen-bonding interaction between DPA molecules and the skeleton of
1
induces the "turn-on" fluorescence sensing of DPA behavior.
A Zn(
ii
) MOF for turn-on fluorescent sensor matrix of DPA detection is synthesized. DFT calculations show the sensing behavior was induced by the intermolecular PET transition and hydrogen-bonding interaction.