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Evaluation of poly (L-lactic acid) monofilaments with high mechanical performance in vitro degradation
Ist Teil von
Journal of materials science, 2022-03, Vol.57 (11), p.6361-6371
Ort / Verlag
New York: Springer US
Erscheinungsjahr
2022
Link zum Volltext
Quelle
SpringerNature Journals
Beschreibungen/Notizen
Nowadays, the degradation properties of poly (L-lactic acid) (PLLA) braided stents are still not well understood. The main challenge relies on the unknown degradation behavior of the PLLA monofilaments, which is the fundamental element of the braided stent. In this paper, the solid-state drawn PLLA monofilament in vitro degradation has been studied. A one-year experiment data was conducted to evaluate degradation properties, including the mass loss, morphology, characterization, and mechanical properties. Within the first 3 months, changes in the mass loss, crystallinity, and mechanical performance of the monofilament were very gentle. The monofilament molecular weight was significantly reduced after each degradation stage and decreased by more than 90% at the end of the one-year degradation. Moreover, the mechanical properties of the annealed monofilament were retained better than that of the unannealed monofilament after 6 months. Therefore, this study may provide preliminary experimental references for evaluating the degradation performance of PLLA braided stents.