Details

Autor(en) / Beteiligte

• Cheng, Dongping
• Wu, Lijun
• Deng, Zhiteng
• Xu, Xiaoliang
• Yan, Jizhong

Titel

2,3-Dichloro-5,6-dicyano-1,4-benzoquinone (DDQ)-Mediated C(sp2)-C(sp3) Cross-Dehydrogenative Coupling Reaction: [alpha]-Alkylation of Push-Pull Enamines and [alpha]-Oxo Ketene Dithioacetals

Ist Teil von

• Advanced synthesis & catalysis, 2017-12, Vol.359 (24), p.4317

Ort / Verlag

Heidelberg: Wiley Subscription Services, Inc

Erscheinungsjahr

2017

Link zum Volltext

Quelle

Wiley Online Library (Online service)

Beschreibungen/Notizen

• A novel, metal-free cross-dehydrogenative coupling (CDC) reaction of C(sp2)-H bonds of enamines and [alpha]-oxo ketene dithioacetals with C(sp3)-H bonds of 1,3-diarylpropenes mediated by 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) is reported. The [alpha]-alkylation products are obtained with moderate to good yields. The method provides an efficient and alternative strategy for the synthesis of the corresponding products.