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GW28-e0517 Protective effect of water-soluble chitosan on rat myocardial ischemia reperfusion injury by inhibiting the inflammatory response
Ist Teil von
Journal of the American College of Cardiology, 2017-10, Vol.70 (16), p.C133-C133
Ort / Verlag
New York: Elsevier Inc
Erscheinungsjahr
2017
Link zum Volltext
Quelle
Elsevier ScienceDirect Journals Complete
Beschreibungen/Notizen
Among them, the IRI model group and each dose group WSC rats by left thoracotomy anterior interventricular branch of left coronary artery was ligated to establish IRI rat model, the rats in the sham operation group only isolated without ligation of the left anterior descending coronary artery. In IRI model group rats myocardial fibers showed disorder, boundary was not clear, and lightly stained cytoplasm, nucleus condensed or dissolved, a large number of inflammatory cells infiltration, hyperemia, congestion, myocardial fiber stripes disappear, myocardial tissue necrosis were observed.