PloS one, 2020-06, Vol.15 (6), p.e0229891
2020
Details
- Autor(en) / Beteiligte
- Titel
- A facile sonochemical protocol for synthesis of 3-amino- and 4-amino-1,2,4-triazole derived Schiff bases as potential antibacterial agents
- Ist Teil von
- PloS one, 2020-06, Vol.15 (6), p.e0229891
- Ort / Verlag
- San Francisco: Public Library of Science
- Erscheinungsjahr
- 2020
- Link zum Volltext
- Quelle
- EZB Electronic Journals Library
- Beschreibungen/Notizen
- A facile method has been developed for the synthesis of Schiff bases derived from substituted and unsubstituted 3-amino- and 4-amino-1,2,4-triazoles. Condensation of the aminotrizoles with a variety of aromatic aldehydes afforded desired Schiff bases in excellent yields in 3-5 minutes of exposure to ultra-sound. The synthesized compounds were characterized by means of IR, .sup.1 HNMR and Mass spectrometry. The synthesized compounds were also screened for their antibacterial potential against Gram-negative (Escherichia coli, Shigella sonnei, Pseudomonas aeruginosa and Salmonella typhi) and two Gram-positive (Staphylococcus aureus and Bacillus subtilis) strains.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1932-6203eISSN: 1932-6203DOI: 10.1371/journal.pone.0229891Titel-ID: cdi_plos_journals_2409625415
- Format
- –
- Schlagworte
- Aldehydes, Antibacterial agents, Antifungal agents, Antiinfectives and antibacterials, Backup software, Biology and Life Sciences, Chemistry, Chemotherapy, E coli, Education, Escherichia coli, Imines, Mass spectrometry, Mass spectroscopy, Medicine and Health Sciences, Methods, Pharmaceutical chemistry, Physical Sciences, Pseudomonas aeruginosa, Research and Analysis Methods, Salmonella, Schiff bases, Spectroscopy, Staphylococcus aureus infections, Synthesis, Testing, Triazoles