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The first myriapod genome sequence reveals conservative arthropod gene content and genome organisation in the centipede Strigamia maritima
PLoS biology, 2014-11, Vol.12 (11), p.e1002005-e1002005
2014
Volltextzugriff (PDF)

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Autor(en) / Beteiligte
Titel
The first myriapod genome sequence reveals conservative arthropod gene content and genome organisation in the centipede Strigamia maritima
Ist Teil von
  • PLoS biology, 2014-11, Vol.12 (11), p.e1002005-e1002005
Ort / Verlag
United States: Public Library of Science (PLoS)
Erscheinungsjahr
2014
Quelle
MEDLINE
Beschreibungen/Notizen
  • Myriapods (e.g., centipedes and millipedes) display a simple homonomous body plan relative to other arthropods. All members of the class are terrestrial, but they attained terrestriality independently of insects. Myriapoda is the only arthropod class not represented by a sequenced genome. We present an analysis of the genome of the centipede Strigamia maritima. It retains a compact genome that has undergone less gene loss and shuffling than previously sequenced arthropods, and many orthologues of genes conserved from the bilaterian ancestor that have been lost in insects. Our analysis locates many genes in conserved macro-synteny contexts, and many small-scale examples of gene clustering. We describe several examples where S. maritima shows different solutions from insects to similar problems. The insect olfactory receptor gene family is absent from S. maritima, and olfaction in air is likely effected by expansion of other receptor gene families. For some genes S. maritima has evolved paralogues to generate coding sequence diversity, where insects use alternate splicing. This is most striking for the Dscam gene, which in Drosophila generates more than 100,000 alternate splice forms, but in S. maritima is encoded by over 100 paralogues. We see an intriguing linkage between the absence of any known photosensory proteins in a blind organism and the additional absence of canonical circadian clock genes. The phylogenetic position of myriapods allows us to identify where in arthropod phylogeny several particular molecular mechanisms and traits emerged. For example, we conclude that juvenile hormone signalling evolved with the emergence of the exoskeleton in the arthropods and that RR-1 containing cuticle proteins evolved in the lineage leading to Mandibulata. We also identify when various gene expansions and losses occurred. The genome of S. maritima offers us a unique glimpse into the ancestral arthropod genome, while also displaying many adaptations to its specific life history.
Sprache
Englisch
Identifikatoren
ISSN: 1545-7885, 1544-9173
eISSN: 1545-7885
DOI: 10.1371/journal.pbio.1002005
Titel-ID: cdi_plos_journals_1685009531
Format
–
Schlagworte
Animals, Arthropods - genetics, Biology and Life Sciences, Circadian Rhythm Signaling Peptides and Proteins - genetics, Colleges & universities, DNA Methylation, Evolution, Molecular, Female, Genes, Genome, Genome, Mitochondrial, Genomes, Genomics, Genètica animal, Genètica evolutiva, Hormones - genetics, Insects, Male, Multigene Family, Phylogenetics, Phylogeny, Polymorphism, Genetic, Project management, Protein Kinases - genetics, Proteins, Receptors, Odorant - genetics, RNA, Untranslated - genetics, Scholarships & fellowships, Selenoproteins - genetics, Sex Chromosomes, Synteny, Transcription Factors - genetics

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