Details

Autor(en) / Beteiligte

• HOTTA, Takahide
• ABETA, Satoshi
• KOIKE, Hidemi
• YOSHINO, Yoshikazu

Titel

The Pseudomyopathic Form of Guillain-Barre Syndrome

Ist Teil von

• JOURNAL OF THE KYORIN MEDICAL SOCIETY, 1997/03/31, Vol.28(1), pp.65-71

Ort / Verlag

The Kyorin Medical Society

Erscheinungsjahr

1997

Link zum Volltext

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Most cases of Guillain-Barre syndrome (GBS) show distally dominant limb weakness or proximally as well as distally even limb weakness. But some cases are known to present with proximally dominant motor disturbances. This clinical form is designated as the pseudomyopathic form, one case of which we experienced and reported in this paper. Among totally 17 cases of GBS admitted in our department during about 8 years, 2 cases (12%) showed the pseudomyopathic form. There were no differences in clinical findings and laboratory examinations between the usual form and the pseudomyopathic form, except for the distribution of muscle weakness. Although the mechanism causing the pseudomyopathic form has not been elucidated, we proposed that predominant damage to medially placed ventral roots innervating proximal limb muscles, compared with little damage to laterally placed ventral roots innervating distal limb muscles could give rise to the pseudomyopathic form. Concerning the pathogenesis of GBS, autoimmune damage to nerve involving anti-ganglioside antibody has recently been proved. But almost selective da-mage to the motor nerve still remains unexplained. For this clarification, the analysis of possible antigenic substances in the ventral and dorsal roots of spinal nerves would be rewarding.