Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist gegebenenfalls nur via VPN oder Shibboleth (DFN-AAI) möglich. mehr Informationen...
The Role of and the Place of Method Validation in the Quality Assurance and Quality Control (QA/QC) System
Ist Teil von
Critical reviews in analytical chemistry, 2007-07, Vol.37 (3), p.173-190
Ort / Verlag
Boca Raton: Taylor & Francis Group
Erscheinungsjahr
2007
Link zum Volltext
Quelle
Taylor & Francis
Beschreibungen/Notizen
One of the main developmental trends in chemical analytics is the determination of analytes at ever decreasing detection levels in samples with increasingly complex matrices. This is an extremely difficult and complicated task therefore it poses a great challenge to analytical chemists, and it requires that appropriate attention be paid to the Quality Assurance and Quality Control (QA/QC) of the obtained measurements. In this article QA/QC system is described. Following topics are discussed: (1) measurement uncertainty, (2) traceability of analytical results, (3) reference materials, (4) interlaboratory comparisons and (5) method validation. The problems and challenges during method validation process are presented.