Details

Autor(en) / Beteiligte

• Strub, Daniel Jan
• Talma, Michał
• Strub, Maria
• Rut, Wioletta
• Zmudzinski, Mikolaj
• Brud, Władysław
• Neyts, Johan
• Vangeel, Laura
• Zhang, Linlin
• Sun, Xinyuanyuan
• Lv, Zongyang
• Nayak, Digant
• Olsen, Shaun K
• Hilgenfeld, Rolf
• Jochmans, Dirk
• Drąg, Marcin

Titel

Evaluation of the anti-SARS-CoV-2 properties of essential oils and aromatic extracts

Ist Teil von

• Scientific reports, 2022-08, Vol.12 (1), p.14230-14230, Article 14230

Ort / Verlag

England: Nature Publishing Group

Erscheinungsjahr

2022

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Essential oils and aromatic extracts (oleoresins, absolutes, concretes, resinoids) are often used as food flavorings and constituents of fragrance compositions. The flavor and fragrance industry observed significant growth in the sales of some natural materials during the COVID-19 outbreak. Some companies worldwide are making false claims regarding the effectiveness of their essential oils or blends (or indirectly point toward this conclusion) against coronaviruses, even though the available data on the activity of plant materials against highly pathogenic human coronaviruses are very scarce. Our exploratory study aimed to develop pioneering knowledge and provide the first experimental results on the inhibitory properties of hundreds of flavor and fragrance materials against SARS-CoV-2 main and papain-like proteases and the antiviral potential of the most active protease inhibitors. As essential oils are volatile products, they could provide an interesting therapeutic strategy for subsidiary inhalation in the long term.