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A Single-Step Genome-Wide Association Study for Semen Traits of Egyptian Buffalo Bulls
Ist Teil von
Animals (Basel), 2023-12, Vol.13 (24), p.3758
Ort / Verlag
Switzerland: MDPI AG
Erscheinungsjahr
2023
Link zum Volltext
Quelle
EZB Free E-Journals
Beschreibungen/Notizen
The present study aimed to contribute to the limited research on buffalo (
) semen traits by incorporating genomic data. A total of 8465 ejaculates were collected. The genotyping procedure was conducted using the Axiom
Buffalo Genotyping 90 K array designed by the Affymetrix Expert Design Program. After conducting a quality assessment, we utilized 67,282 SNPs genotyped in 192 animals. We identified several genomic loci explaining high genetic variance by employing single-step genomic evaluation. The aforementioned regions were located on buffalo chromosomes no. 3, 4, 6, 7, 14, 16, 20, 22, and the X-chromosome. The X-chromosome exhibited substantial influence, accounting for 4.18, 4.59, 5.16, 5.19, and 4.31% of the genomic variance for ejaculate volume, mass motility, livability, abnormality, and concentration, respectively. In the examined genomic regions, we identified five novel candidate genes linked to male fertility and spermatogenesis, four in the X-chromosome and one in chromosome no. 16. Additional extensive research with larger sample sizes and datasets is imperative to validate these findings and evaluate their applicability for genomic selection.