Details

Autor(en) / Beteiligte

• Wallner, Stephanie
• Peters, Sebastian
• Pitzer, Claudia
• Resch, Herbert
• Bogdahn, Ulrich
• Schneider, Armin

Titel

The Granulocyte-colony stimulating factor has a dual role in neuronal and vascular plasticity

Ist Teil von

• Frontiers in cell and developmental biology, 2015-08, Vol.3, p.48-48

Ort / Verlag

Switzerland: Frontiers Research Foundation

Erscheinungsjahr

2015

Link zum Volltext

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• Granulocyte-colony stimulating factor (G-CSF) is a growth factor that has originally been identified several decades ago as a hematopoietic factor required mainly for the generation of neutrophilic granulocytes, and is in clinical use for that. More recently, it has been discovered that G-CSF also plays a role in the brain as a growth factor for neurons and neural stem cells, and as a factor involved in the plasticity of the vasculature. We review and discuss these dual properties in view of the neuroregenerative potential of this growth factor.