Details

Autor(en) / Beteiligte

• Johnson, Warren Victor

Titel

Introduction to computer modeling using Jmol in an introductory biochemistry lab course

Ist Teil von

• The FASEB journal, 2009-04, Vol.23 (S1)

Erscheinungsjahr

2009

Link zum Volltext

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• Abstract only It has been fifty years since the first three‐dimensional (3‐D) protein structure was published. There are tens of thousands of structures available in the protein databank. The manipulation of 3‐D structures can be very helpful to students seeking to understand protein structure and function. The easy to use, open source freeware, Jmol works well to enable beginning biochemistry students to examine structures of biomolecules. Students in the first two sessions of a one‐semester biochemistry laboratory course quickly and easily learned to use Jmol to investigate the structures of various biomolecules in the protein databank. They prepared figures to illustrate particular features of an enzyme and prepared a report on the structure and function of an enzyme that included these figures. Later in this course students made use of this knowledge to design images for a poster presentation that explains the mechanism of an enzyme that they purified and characterized in the laboratory. Students learned how 3‐D models are determined, how to access information from the protein databank, how to read and modify files in the database, how to view and manipulate 3‐D models with Jmol, and how to prepare figures in Jmol for insertion into a report. http://www.uwgb.edu/johnson