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Green synthesis of carbon dots from pork and application as nanosensors for uric acid detection
Ist Teil von
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2018-02, Vol.190, p.360-367
Ort / Verlag
Elsevier B.V
Erscheinungsjahr
2018
Link zum Volltext
Quelle
Elsevier ScienceDirect Journals Complete
Beschreibungen/Notizen
In this work, a green, simple, economical method was developed in the synthesis of fluorescent carbon dots using pork as carbon source. The as-prepared carbon dots exhibit exceptional advantages including high fluorescent quantum yield (17.3%) and satisfactory chemical stability. The fluorescence of carbon dots based nanosensor can be selectively and efficiently quenched by uric acid. This phenomenon was used to develop a fluorescent method for facile detection of uric acid within a linear range of 0.1–100μM and 100–500μM, with a detection limit of 0.05μM (S/N=3). Finally, the proposed method was successfully applied in the determination of uric acid in human serum and urine samples with satisfactory recoveries, which suggested that the new nanosensors have great prospect toward the detection of uric acid in human fluids.
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•Fluorescent carbon dots (CDs) were synthesized using pork.•The as-prepared CDs show high long-term stability.•Uric acid (UA) can quench the fluorescence of CDs owing to static quenching.•The CDs were used for the sensitive and selective detection of UA in human fluid.