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Aging-affiliated post-translational modifications of skeletal muscle myosin affect biochemical properties, myofibril structure, muscle function, and proteostasis

Aging cell, 2024-03, p.e14134-e14134

2024

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Drosophila myosin mutants model the disparate severity of type 1 and type 2B distal arthrogryposis and indicate an enhanced actin affinity mechanism

Skeletal muscle, 2020-08, Vol.10 (1), p.1-24, Article 24

2020

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The NADPH metabolic network regulates human αB-crystallin cardiomyopathy and reductive stress in Drosophila melanogaster

PLoS genetics, 2013-06, Vol.9 (6), p.e1003544-e1003544

2013

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A Drosophila model of dominant inclusion body myopathy type 3 shows diminished myosin kinetics that reduce muscle power and yield myofibrillar defects

Disease models & mechanisms, 2017-06, Vol.10 (6), p.761-771

2017

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Expression of the inclusion body myopathy 3 mutation in Drosophila depresses myosin function and stability and recapitulates muscle inclusions and weakness

Molecular biology of the cell, 2012-06, Vol.23 (11), p.2057-2065

2012

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X-ray diffraction from flight muscle with a headless myosin mutation: implications for interpreting reflection patterns

Frontiers in physiology, 2014-10, Vol.5, p.416-416

2014

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Suppression of myopathic lamin mutations by muscle-specific activation of AMPK and modulation of downstream signaling

Human molecular genetics, 2019-02, Vol.28 (3), p.351-371

2019

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Alternative S2 Hinge Regions of the Myosin Rod Differentially Affect Muscle Function, Myofibril Dimensions and Myosin Tail Length

Journal of molecular biology, 2007-04, Vol.367 (5), p.1312-1329

2007

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A Restrictive Cardiomyopathy Mutation in an Invariant Proline at the Myosin Head/Rod Junction Enhances Head Flexibility and Function, Yielding Muscle Defects in Drosophila

Journal of molecular biology, 2016-06, Vol.428 (11), p.2446-2461

2016

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Drosophila UNC-45 accumulates in embryonic blastoderm and in muscles, and is essential for muscle myosin stability

Journal of cell science, 2011-03, Vol.124 (5), p.699-705

2011

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Manipulating Levels of Stress‐Response Proteins in a Drosophila Model of Myosin‐Based Inclusion Body Myopathy 3 Worsens Muscle Dysfunction

The FASEB journal, 2020-04, Vol.34 (S1), p.1-1

2020

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Variable N-terminal Regions of Muscle Myosin Heavy Chain Modulate ATPase Rate and Actin Sliding Velocity

The Journal of biological chemistry, 2003-05, Vol.278 (19), p.17475-17482

2003

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A Drosophila Model of Myosin-Based Inclusion Body Myopathy Type 3: Effects on Muscle Structure, Muscle Function and Aggregated Protein Profiles

Biophysical journal, 2015-01, Vol.108 (2), p.304a-304a

2015

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The myosin converter domain modulates muscle performance

Nature cell biology, 2002-04, Vol.4 (4), p.312-317

2002

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A Drosophila model of dominant inclusion body myopathy 3 shows diminished myosin kinetics that reduce muscle power and yield myofibrillar defects

Disease models & mechanisms, 2017-01

2017

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Exploration and Suppression of Tau-Induced Cardiac and Skeletal Muscle Defects in a Drosophila Model

Biophysical journal, 2013-01, Vol.104 (2), p.486a-486a

2013

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Alleviation of Skeletal Muscle Defects Induced by Huntington's Disease-causing Amyloid by Modulating TOR Pathway in a Drosophila Model

Biophysical journal, 2013-01, Vol.104 (2), p.483a-483a

2013

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The NADPH Metabolic Network Regulates Human [alpha]B-crystallin Cardiomyopathy and Reductive Stress in Drosophila melanogaster: e1003544

PLoS genetics, 2013-06, Vol.9 (6)

2013

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An Alternative Domain Near the Nucleotide-binding Site of Drosophila Muscle Myosin Affects ATPase Kinetics

Journal of molecular biology, 2005-10, Vol.353 (1), p.14-25

2005

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Assembly of thick filaments and myofibrils occurs in the absence of the myosin head

The EMBO journal, 1999-04, Vol.18 (7), p.1793-1804

1999

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The E706K IBM3 Myosin Mutation Depresses the Chemomechanical Properties and Increases the Lability of the Molecular Motor

Biophysical journal, 2011-02, Vol.100 (3), p.129a-129a

2011

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Drosophila UNC-45 accumulates in embryonic blastoderm and in muscles, and is essential for muscle myosin stability

Development (Cambridge), 2011-03, Vol.138 (6), p.e1-e1

2011

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Myles Brand’s Collegiate Model and the Post-Amateurism World of College Sports

Journal of intercollegiate sport, 2021-12, Vol.14 (3)

2021

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The NADPH Metabolic Network Regulates Human alpha B-crystallin Cardiomyopathy and Reductive Stress in Drosophila melanogaster. e1003544

PLoS genetics, 2013-06, Vol.9 (6)

2013

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Guidelines and Resources for Conducting an Environmental Crime Investigation in the United States

Environmental forensics, 2002-06, Vol.3 (2), p.91-113

2002

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Aging-affiliated post-translational modifications of skeletal muscle myosin affect biochemical properties, myofibril structure, muscle function, and proteostasis

Drosophila myosin mutants model the disparate severity of type 1 and type 2B distal arthrogryposis and indicate an enhanced actin affinity mechanism

The NADPH metabolic network regulates human αB-crystallin cardiomyopathy and reductive stress in Drosophila melanogaster

A Drosophila model of dominant inclusion body myopathy type 3 shows diminished myosin kinetics that reduce muscle power and yield myofibrillar defects

Expression of the inclusion body myopathy 3 mutation in Drosophila depresses myosin function and stability and recapitulates muscle inclusions and weakness

X-ray diffraction from flight muscle with a headless myosin mutation: implications for interpreting reflection patterns

Suppression of myopathic lamin mutations by muscle-specific activation of AMPK and modulation of downstream signaling

Alternative S2 Hinge Regions of the Myosin Rod Differentially Affect Muscle Function, Myofibril Dimensions and Myosin Tail Length

A Restrictive Cardiomyopathy Mutation in an Invariant Proline at the Myosin Head/Rod Junction Enhances Head Flexibility and Function, Yielding Muscle Defects in Drosophila

Drosophila UNC-45 accumulates in embryonic blastoderm and in muscles, and is essential for muscle myosin stability

Manipulating Levels of Stress‐Response Proteins in a Drosophila Model of Myosin‐Based Inclusion Body Myopathy 3 Worsens Muscle Dysfunction

Variable N-terminal Regions of Muscle Myosin Heavy Chain Modulate ATPase Rate and Actin Sliding Velocity

A Drosophila Model of Myosin-Based Inclusion Body Myopathy Type 3: Effects on Muscle Structure, Muscle Function and Aggregated Protein Profiles

The myosin converter domain modulates muscle performance

A Drosophila model of dominant inclusion body myopathy 3 shows diminished myosin kinetics that reduce muscle power and yield myofibrillar defects

Exploration and Suppression of Tau-Induced Cardiac and Skeletal Muscle Defects in a Drosophila Model

Alleviation of Skeletal Muscle Defects Induced by Huntington's Disease-causing Amyloid by Modulating TOR Pathway in a Drosophila Model

The NADPH Metabolic Network Regulates Human [alpha]B-crystallin Cardiomyopathy and Reductive Stress in Drosophila melanogaster: e1003544

An Alternative Domain Near the Nucleotide-binding Site of Drosophila Muscle Myosin Affects ATPase Kinetics

Assembly of thick filaments and myofibrils occurs in the absence of the myosin head

The E706K IBM3 Myosin Mutation Depresses the Chemomechanical Properties and Increases the Lability of the Molecular Motor

Drosophila UNC-45 accumulates in embryonic blastoderm and in muscles, and is essential for muscle myosin stability

Myles Brand’s Collegiate Model and the Post-Amateurism World of College Sports

The NADPH Metabolic Network Regulates Human alpha B-crystallin Cardiomyopathy and Reductive Stress in Drosophila melanogaster. e1003544

Guidelines and Resources for Conducting an Environmental Crime Investigation in the United States

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