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Caspase-2 regulates oncogene-induced senescence

Oncotarget, 2014-07, Vol.5 (14), p.5845-5847

2014

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Strategies, design, and chemistry in siRNA delivery systems

Advanced drug delivery reviews, 2019-04, Vol.144, p.133-147

2019

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Carbon Dots for Efficient Small Interfering RNA Delivery and Gene Silencing in Plants

Plant physiology (Bethesda), 2020-10, Vol.184 (2), p.647-657

2020

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RNAi-based therapeutics and tumor targeted delivery in cancer

Advanced drug delivery reviews, 2022-03, Vol.182, p.114113-114113, Article 114113

2022

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The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs

Nature nanotechnology, 2019-12, Vol.14 (12), p.1084-1087

2019

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Tumor Acidity-Sensitive Polymeric Vector for Active Targeted siRNA Delivery

Journal of the American Chemical Society, 2015-12, Vol.137 (48), p.15217-15224

2015

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Recent advances in siRNA delivery mediated by lipid-based nanoparticles

Advanced drug delivery reviews, 2020, Vol.154-155, p.64-78

2020

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Single Ascending Dose Study of a Short Interfering RNA Targeting Lipoprotein(a) Production in Individuals With Elevated Plasma Lipoprotein(a) Levels

JAMA : the journal of the American Medical Association, 2022-05, Vol.327 (17), p.1679

2022

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Molecular-Targeted Immunotherapeutic Strategy for Melanoma via Dual-Targeting Nanoparticles Delivering Small Interfering RNA to Tumor-Associated Macrophages

ACS nano, 2017-09, Vol.11 (9), p.9536-9549

2017

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A Highly Durable RNAi Therapeutic Inhibitor of PCSK9

The New England journal of medicine, 2017-01, Vol.376 (1), p.41-51

2017

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Plasma exosomes can deliver exogenous short interfering RNA to monocytes and lymphocytes

Nucleic acids research, 2012-09, Vol.40 (17), p.e130

2012

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Image-based analysis of lipid nanoparticle-mediated siRNA delivery, intracellular trafficking and endosomal escape

Nature biotechnology, 2013-07, Vol.31 (7), p.638-646

2013

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Inclisiran in Patients at High Cardiovascular Risk with Elevated LDL Cholesterol

The New England journal of medicine, 2017-04, Vol.376 (15), p.1430-1440

2017

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Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling

Nature biotechnology, 2013-07, Vol.31 (7), p.653-658

2013

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Nanoscale Metal–Organic Frameworks for the Co-Delivery of Cisplatin and Pooled siRNAs to Enhance Therapeutic Efficacy in Drug-Resistant Ovarian Cancer Cells

Journal of the American Chemical Society, 2014-04, Vol.136 (14), p.5181-5184

2014

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Preclinical and clinical development of siRNA-based therapeutics

Advanced drug delivery reviews, 2015-06, Vol.87, p.108-119

2015

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Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo

Angewandte Chemie (International ed.), 2012-08, Vol.51 (34), p.8529-8533

International ed. in English, 2012

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Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer

Nature (London), 2017-06, Vol.546 (7659), p.498-503

2017

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Rekindling RNAi Therapy: Materials Design Requirements for In Vivo siRNA Delivery

Advanced materials (Weinheim), 2019-12, Vol.31 (49), p.e1903637-n/a

2019

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Impact of enhanced metabolic stability on pharmacokinetics and pharmacodynamics of GalNAc-siRNA conjugates

Nucleic acids research, 2017-11, Vol.45 (19), p.10969

2017

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Specific hepatic delivery of procollagen α1(I) small interfering RNA in lipid‐like nanoparticles resolves liver fibrosis

Hepatology (Baltimore, Md.), 2015-10, Vol.62 (4), p.1285-1297

2015

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Nanoparticles-based drug delivery and gene therapy for breast cancer: Recent advancements and future challenges

Seminars in cancer biology, 2021-02, Vol.69, p.226-237

2021

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Advanced siRNA Designs Further Improve In Vivo Performance of GalNAc-siRNA Conjugates

Molecular therapy, 2018-03, Vol.26 (3), p.708-717

2018

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A review of nanocarriers for the delivery of small interfering RNA

Biomaterials, 2012-10, Vol.33 (29), p.7138-7150

2012

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Small RNA combination therapy for lung cancer

Proceedings of the National Academy of Sciences - PNAS, 2014-08, Vol.111 (34), p.12281-12281

2014

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Caspase-2 regulates oncogene-induced senescence

Strategies, design, and chemistry in siRNA delivery systems

Carbon Dots for Efficient Small Interfering RNA Delivery and Gene Silencing in Plants

RNAi-based therapeutics and tumor targeted delivery in cancer

The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs

Tumor Acidity-Sensitive Polymeric Vector for Active Targeted siRNA Delivery

Recent advances in siRNA delivery mediated by lipid-based nanoparticles

Single Ascending Dose Study of a Short Interfering RNA Targeting Lipoprotein(a) Production in Individuals With Elevated Plasma Lipoprotein(a) Levels

Molecular-Targeted Immunotherapeutic Strategy for Melanoma via Dual-Targeting Nanoparticles Delivering Small Interfering RNA to Tumor-Associated Macrophages

A Highly Durable RNAi Therapeutic Inhibitor of PCSK9

Plasma exosomes can deliver exogenous short interfering RNA to monocytes and lymphocytes

Image-based analysis of lipid nanoparticle-mediated siRNA delivery, intracellular trafficking and endosomal escape

Inclisiran in Patients at High Cardiovascular Risk with Elevated LDL Cholesterol

Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling

Nanoscale Metal–Organic Frameworks for the Co-Delivery of Cisplatin and Pooled siRNAs to Enhance Therapeutic Efficacy in Drug-Resistant Ovarian Cancer Cells

Preclinical and clinical development of siRNA-based therapeutics

Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo

Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer

Rekindling RNAi Therapy: Materials Design Requirements for In Vivo siRNA Delivery

Impact of enhanced metabolic stability on pharmacokinetics and pharmacodynamics of GalNAc-siRNA conjugates

Specific hepatic delivery of procollagen α1(I) small interfering RNA in lipid‐like nanoparticles resolves liver fibrosis

Nanoparticles-based drug delivery and gene therapy for breast cancer: Recent advancements and future challenges

Advanced siRNA Designs Further Improve In Vivo Performance of GalNAc-siRNA Conjugates

A review of nanocarriers for the delivery of small interfering RNA

Small RNA combination therapy for lung cancer

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