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A New View into the Regulation of Purine Metabolism: The Purinosome

Trends in biochemical sciences (Amsterdam. Regular ed.), 2017-02, Vol.42 (2), p.141-154

2017

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Human de novo purine biosynthesis

Critical reviews in biochemistry and molecular biology, 2021-01, Vol.56 (1), p.1-16

2021

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The Purinosome: A Case Study for a Mammalian Metabolon

Annual review of biochemistry, 2022-06, Vol.91, p.89

2022

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The roles of molecular chaperones in regulating cell metabolism

FEBS letters, 2023-07, Vol.597 (13), p.1681-1701

2023

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Detecting Purinosome Metabolon Formation with Fluorescence Microscopy

Methods in molecular biology (Clifton, N.J.), 2018, Vol.1764, p.279

2018

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Microtubule-directed transport of purine metabolons drives their cytosolic transit to mitochondria

Proceedings of the National Academy of Sciences - PNAS, 2018-12, Vol.115 (51), p.13009-13014

2018

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Hypoxia drives the assembly of the multienzyme purinosome complex

The Journal of biological chemistry, 2020-07, Vol.295 (28), p.9551-9566

2020

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Spatial colocalization and functional link of purinosomes with mitochondria

Science (American Association for the Advancement of Science), 2016-02, Vol.351 (6274), p.733-737

2016

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Purinosome formation as a function of the cell cycle

Proceedings of the National Academy of Sciences - PNAS, 2015-02, Vol.112 (5), p.1368-1373

2015

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Purine biosynthetic enzymes assemble into liquid-like condensates dependent on the activity of chaperone protein HSP90

The Journal of biological chemistry, 2022-05, Vol.298 (5), p.101845-101845, Article 101845

2022

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Replication protein A dynamically regulates monoubiquitination of proliferating cell nuclear antigen

The Journal of biological chemistry, 2019-03, Vol.294 (13), p.5157-5168

2019

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Flexibility of PCNA-protein interface accommodates differential binding partners

PloS one, 2014-07, Vol.9 (7), p.e102481-e102481

2014

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Quantitative Analysis of Purine Nucleotides Indicates That Purinosomes Increase de Novo Purine Biosynthesis

The Journal of biological chemistry, 2015-03, Vol.290 (11), p.6705-6713

2015

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Role of HSP90 in the Regulation of de Novo Purine Biosynthesis

Biochemistry (Easton), 2018-06, Vol.57 (23), p.3217-3221

2018

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Mapping Post-Translational Modifications of de Novo Purine Biosynthetic Enzymes: Implications for Pathway Regulation

Journal of proteome research, 2019-05, Vol.18 (5), p.2078-2087

2019

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Selective Inhibition of STAT3 Phosphorylation Using a Nuclear-Targeted Kinase Inhibitor

ACS chemical biology, 2017-09, Vol.12 (9), p.2371-2378

2017

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Conformational changes involving ammonia tunnel formation and allosteric control in GMP synthetase

Archives of biochemistry and biophysics, 2014-03, Vol.545, p.22-32

2014

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Identification of FAK substrate peptides via colorimetric screening of a one-bead one-peptide combinatorial library

Journal of peptide science, 2015-04, Vol.21 (4), p.302-311

2015

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Identifying cancer genome‐wide small molecule synthetic lethality in PCNA interaction networks

The FASEB journal, 2013-04, Vol.27 (S1)

2013

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Identification of FAK substrate peptides via colorimetric screening of a one-bead one-peptide combinatorial library: FAK SUBSTRATE PEPTIDES

Journal of peptide science, 2015-04, Vol.21 (4), p.302-311

2015

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Observations on the Cellular Dynamics of a Metabolic Complex, the Purinosome

The FASEB journal, 2016-04, Vol.30 (S1)

2016

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Electrohydrodynamic encapsulation of cisplatin in poly (lactic-co-glycolic acid) nanoparticles for controlled drug delivery

Nanomedicine, 2016-10, Vol.12 (7), p.1919-1929

2016

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Investigation of a MAPKKKα Kinase Interactions with Phosphatase Mutants Using a Yeast Two‐Hybrid Approach

The FASEB journal, 2007-04, Vol.21 (5), p.A619-A619

2007

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Abstract-to-publication ratio for papers presented at scientific meetings: a quality marker for UK emergency medicine research

Emergency medicine journal : EMJ, 2007-06, Vol.24 (6), p.425-426

2007

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Electrohydrodynamic fabrication of core-shell PLGA nanoparticles with controlled release of cisplatin for enhanced cancer treatment

International journal of nanomedicine, 2017-01, Vol.12, p.3913-3926

2017

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A New View into the Regulation of Purine Metabolism: The Purinosome

Human de novo purine biosynthesis

The Purinosome: A Case Study for a Mammalian Metabolon

The roles of molecular chaperones in regulating cell metabolism

Detecting Purinosome Metabolon Formation with Fluorescence Microscopy

Microtubule-directed transport of purine metabolons drives their cytosolic transit to mitochondria

Hypoxia drives the assembly of the multienzyme purinosome complex

Spatial colocalization and functional link of purinosomes with mitochondria

Purinosome formation as a function of the cell cycle

Purine biosynthetic enzymes assemble into liquid-like condensates dependent on the activity of chaperone protein HSP90

Replication protein A dynamically regulates monoubiquitination of proliferating cell nuclear antigen

Flexibility of PCNA-protein interface accommodates differential binding partners

Quantitative Analysis of Purine Nucleotides Indicates That Purinosomes Increase de Novo Purine Biosynthesis

Role of HSP90 in the Regulation of de Novo Purine Biosynthesis

Mapping Post-Translational Modifications of de Novo Purine Biosynthetic Enzymes: Implications for Pathway Regulation

Selective Inhibition of STAT3 Phosphorylation Using a Nuclear-Targeted Kinase Inhibitor

Conformational changes involving ammonia tunnel formation and allosteric control in GMP synthetase

Identification of FAK substrate peptides via colorimetric screening of a one-bead one-peptide combinatorial library

Identifying cancer genome‐wide small molecule synthetic lethality in PCNA interaction networks

Identification of FAK substrate peptides via colorimetric screening of a one-bead one-peptide combinatorial library: FAK SUBSTRATE PEPTIDES

Observations on the Cellular Dynamics of a Metabolic Complex, the Purinosome

Electrohydrodynamic encapsulation of cisplatin in poly (lactic-co-glycolic acid) nanoparticles for controlled drug delivery

Investigation of a MAPKKKα Kinase Interactions with Phosphatase Mutants Using a Yeast Two‐Hybrid Approach

Abstract-to-publication ratio for papers presented at scientific meetings: a quality marker for UK emergency medicine research

Electrohydrodynamic fabrication of core-shell PLGA nanoparticles with controlled release of cisplatin for enhanced cancer treatment

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