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CD40 agonistic monoclonal antibody APX005M (sotigalimab) and chemotherapy, with or without nivolumab, for the treatment of metastatic pancreatic adenocarcinoma: an open-label, multicentre, phase 1b study

The lancet oncology, 2021-01, Vol.22 (1), p.118-131

2021

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In Vitro and In Vivo Evaluation of the Antifungal Activity of APX001A/APX001 against Candida auris

Antimicrobial agents and chemotherapy, 2018-03, Vol.62 (3)

2018

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ABA is required for the accumulation of APX1 and MBF1c during a combination of water deficit and heat stress

Journal of experimental botany, 2016-10, Vol.67 (18), p.5381-5390

2016

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In Vitro and In Vivo Evaluation of APX001A/APX001 and Other Gwt1 Inhibitors against Cryptococcus

Antimicrobial agents and chemotherapy, 2018-08, Vol.62 (8)

2018

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A Phase I Study of APX005M and Cabiralizumab with or without Nivolumab in Patients with Melanoma, Kidney Cancer, or Non-Small Cell Lung Cancer Resistant to Anti-PD-1/PD-L1

Clinical cancer research, 2021-09, Vol.27 (17), p.4757-4767

2021

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Dual regulation of cytosolic ascorbate peroxidase (APX) by tyrosine nitration and S-nitrosylation

Journal of experimental botany, 2014-02, Vol.65 (2), p.527-538

2014

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Fosmanogepix (APX001) Is Effective in the Treatment of Immunocompromised Mice Infected with Invasive Pulmonary Scedosporiosis or Disseminated Fusariosis

Antimicrobial agents and chemotherapy, 2020-02, Vol.64 (3)

2020

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Expression of SOD and APX genes positively regulates secondary cell wall biosynthesis and promotes plant growth and yield in Arabidopsis under salt stress

Plant molecular biology, 2015-04, Vol.87 (6), p.615-631

2015

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Fosmanogepix (APX001) Is Effective in the Treatment of Pulmonary Murine Mucormycosis Due to Rhizopus arrhizus

Antimicrobial agents and chemotherapy, 2020-05, Vol.64 (6)

2020

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In Vitro Activity of APX001A (Manogepix) and Comparator Agents against 1,706 Fungal Isolates Collected during an International Surveillance Program in 2017

Antimicrobial agents and chemotherapy, 2019-08, Vol.63 (8)

2019

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Efficacy of Delayed Therapy with Fosmanogepix (APX001) in a Murine Model of Candida auris Invasive Candidiasis

Antimicrobial agents and chemotherapy, 2019-11, Vol.63 (11)

2019

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In Situ Characterization of Catalysis and Electrocatalysis Using APXPS

ACS catalysis, 2021-02, Vol.11 (3), p.1464-1484

2021

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In Vivo Pharmacokinetics and Pharmacodynamics of APX001 against Candida spp. in a Neutropenic Disseminated Candidiasis Mouse Model

Antimicrobial agents and chemotherapy, 2018-04, Vol.62 (4)

2018

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APX001 and Other Gwt1 Inhibitor Prodrugs Are Effective in Experimental Coccidioides immitis Pneumonia

Antimicrobial agents and chemotherapy, 2019-02, Vol.63 (2)

2019

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Manogepix (APX001A) In Vitro Activity against Candida auris: Head-to-Head Comparison of EUCAST and CLSI MICs

Antimicrobial agents and chemotherapy, 2020-09, Vol.64 (10)

2020

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APX001A In Vitro Activity against Contemporary Blood Isolates and Candida auris Determined by the EUCAST Reference Method

Antimicrobial agents and chemotherapy, 2018-10, Vol.62 (10)

2018

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Molecular characterization of ascorbate peroxidase (APX) and APX-related (APX-R) genes in Triticum aestivum L

Genomics (San Diego, Calif.), 2020-11, Vol.112 (6), p.4208-4223

2020

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Overexpression of CuZnSOD and APX enhance salt stress tolerance in sweet potato

Plant physiology and biochemistry, 2016-12, Vol.109, p.20-27

2016

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Evaluation of Resistance Development to the Gwt1 Inhibitor Manogepix (APX001A) in Candida Species

Antimicrobial agents and chemotherapy, 2019-12, Vol.64 (1)

2019

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APX-hardness of maximizing Nash social welfare with indivisible items

Information processing letters, 2017-06, Vol.122, p.17-20

Lee, Euiwoong

2017

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APX001 Pharmacokinetic/Pharmacodynamic Target Determination against Aspergillus fumigatus in an In Vivo Model of Invasive Pulmonary Aspergillosis

Antimicrobial agents and chemotherapy, 2019-04, Vol.63 (4)

2019

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Efficacy and Pharmacokinetics of Fosmanogepix (APX001) in the Treatment of Candida Endophthalmitis and Hematogenous Meningoencephalitis in Nonneutropenic Rabbits

Antimicrobial agents and chemotherapy, 2021-02, Vol.65 (3)

2021

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The ascorbate peroxidase APX1 is a direct target of a zinc finger transcription factor ZFP36 and a late embryogenesis abundant protein OsLEA5 interacts with ZFP36 to co-regulate OsAPX1 in seed germination in rice

Biochemical and biophysical research communications, 2018-01, Vol.495 (1), p.339-345

2018

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Significantly Improved Pharmacokinetics Enhances In Vivo Efficacy of APX001 against Echinocandin- and Multidrug-Resistant Candida Isolates in a Mouse Model of Invasive Candidiasis

Antimicrobial agents and chemotherapy, 2018-10, Vol.62 (10)

2018

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Characterization of APX and APX-R gene family in Brassica juncea and B. rapa for tolerance against abiotic stresses

Plant cell reports, 2022-03, Vol.41 (3), p.571-592

2022

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CD40 agonistic monoclonal antibody APX005M (sotigalimab) and chemotherapy, with or without nivolumab, for the treatment of metastatic pancreatic adenocarcinoma: an open-label, multicentre, phase 1b study

In Vitro and In Vivo Evaluation of the Antifungal Activity of APX001A/APX001 against Candida auris

ABA is required for the accumulation of APX1 and MBF1c during a combination of water deficit and heat stress

In Vitro and In Vivo Evaluation of APX001A/APX001 and Other Gwt1 Inhibitors against Cryptococcus

A Phase I Study of APX005M and Cabiralizumab with or without Nivolumab in Patients with Melanoma, Kidney Cancer, or Non-Small Cell Lung Cancer Resistant to Anti-PD-1/PD-L1

Dual regulation of cytosolic ascorbate peroxidase (APX) by tyrosine nitration and S-nitrosylation

Fosmanogepix (APX001) Is Effective in the Treatment of Immunocompromised Mice Infected with Invasive Pulmonary Scedosporiosis or Disseminated Fusariosis

Expression of SOD and APX genes positively regulates secondary cell wall biosynthesis and promotes plant growth and yield in Arabidopsis under salt stress

Fosmanogepix (APX001) Is Effective in the Treatment of Pulmonary Murine Mucormycosis Due to Rhizopus arrhizus

In Vitro Activity of APX001A (Manogepix) and Comparator Agents against 1,706 Fungal Isolates Collected during an International Surveillance Program in 2017

Efficacy of Delayed Therapy with Fosmanogepix (APX001) in a Murine Model of Candida auris Invasive Candidiasis

In Situ Characterization of Catalysis and Electrocatalysis Using APXPS

In Vivo Pharmacokinetics and Pharmacodynamics of APX001 against Candida spp. in a Neutropenic Disseminated Candidiasis Mouse Model

APX001 and Other Gwt1 Inhibitor Prodrugs Are Effective in Experimental Coccidioides immitis Pneumonia

Manogepix (APX001A) In Vitro Activity against Candida auris: Head-to-Head Comparison of EUCAST and CLSI MICs

APX001A In Vitro Activity against Contemporary Blood Isolates and Candida auris Determined by the EUCAST Reference Method

Molecular characterization of ascorbate peroxidase (APX) and APX-related (APX-R) genes in Triticum aestivum L

Overexpression of CuZnSOD and APX enhance salt stress tolerance in sweet potato

Evaluation of Resistance Development to the Gwt1 Inhibitor Manogepix (APX001A) in Candida Species

APX-hardness of maximizing Nash social welfare with indivisible items

APX001 Pharmacokinetic/Pharmacodynamic Target Determination against Aspergillus fumigatus in an In Vivo Model of Invasive Pulmonary Aspergillosis

Efficacy and Pharmacokinetics of Fosmanogepix (APX001) in the Treatment of Candida Endophthalmitis and Hematogenous Meningoencephalitis in Nonneutropenic Rabbits

The ascorbate peroxidase APX1 is a direct target of a zinc finger transcription factor ZFP36 and a late embryogenesis abundant protein OsLEA5 interacts with ZFP36 to co-regulate OsAPX1 in seed germination in rice

Significantly Improved Pharmacokinetics Enhances In Vivo Efficacy of APX001 against Echinocandin- and Multidrug-Resistant Candida Isolates in a Mouse Model of Invasive Candidiasis

Characterization of APX and APX-R gene family in Brassica juncea and B. rapa for tolerance against abiotic stresses

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