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Structure units oriented approach towards collective synthesis of sarpagine-ajmaline-koumine type alkaloids

Nature communications, 2022-02, Vol.13 (1), p.908-908, Article 908

2022

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Safety and Efficacy of AJM300, an Oral Antagonist of α4 Integrin, in Induction Therapy for Patients With Active Ulcerative Colitis

Gastroenterology (New York, N.Y. 1943), 2015-12, Vol.149 (7), p.1775-1783.e2

2015

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Construction of ajmalicine and sanguinarine de novo biosynthetic pathways using stable integration sites in yeast

Biotechnology and bioengineering, 2022-05, Vol.119 (5), p.1314-1326

2022

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Endophytes enhance the production of root alkaloids ajmalicine and serpentine by modulating the terpenoid indole alkaloid pathway in Catharanthus roseus roots

Journal of applied microbiology, 2020-04, Vol.128 (4), p.1128-1142

2020

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Discovery of Unusual Ajmaline‐Macroline Type Bisindole Alkaloids from Alstonia macrophylla by Building Blocks‐Based Molecular Networking

Chemistry : a European journal, 2024-02, Vol.30 (8), p.e202303519-n/a

2024

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De novo biosynthesis of antiarrhythmic alkaloid ajmaline

Nature communications, 2024-01, Vol.15 (1), p.457-457, Article 457

2024

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Modulation of terpenoid indole alkaloid pathway via elicitation with phytosynthesized silver nanoparticles for the enhancement of ajmalicine, a pharmaceutically important alkaloid

Planta, 2024-02, Vol.259 (2), p.30-30, Article 30

2024

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dST-Tiso Interval, a Novel Electrocardiographic Marker of Ventricular Arrhythmia Inducibility in Individuals With Ajmaline-Induced Brugada Type I Pattern

The American journal of cardiology, 2021-11, Vol.159, p.94-99

2021

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Predicting ventricular arrhythmia inducibility in ajmaline-induced brugada type I pattern: validation of the dST-Tiso interval

European heart journal, 2023-11, Vol.44 (Supplement_2)

2023

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Ajmalicine and Reserpine: Indole Alkaloids as Multi-Target Directed Ligands Towards Factors Implicated in Alzheimer's Disease

Molecules (Basel, Switzerland), 2020-04, Vol.25 (7), p.1609

2020

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Methylobacterium ajmalii sp. nov., Isolated From the International Space Station

Frontiers in microbiology, 2021-03, Vol.12, p.639396-639396

2021

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Ajmaline Testing and the Brugada Syndrome

The American journal of cardiology, 2020-11, Vol.135, p.91-98

2020

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Local depolarization abnormalities are the dominant pathophysiologic mechanism for type 1 electrocardiogram in brugada syndrome a study of electrocardiograms, vectorcardiograms, and body surface potential maps during ajmaline provocation

Journal of the American College of Cardiology, 2010-02, Vol.55 (8), p.789-797

2010

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AJM300 (carotegrast methyl), an oral antagonist of α4-integrin, as induction therapy for patients with moderately active ulcerative colitis: a multicentre, randomised, double-blind, placebo-controlled, phase 3 study

The lancet. Gastroenterology & hepatology, 2022-07, Vol.7 (7), p.648-657

2022

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Accumulation of ajmalicine and vinblastine in cell cultures is enhanced by endophytic fungi of Catharanthus roseus cv. Icy Pink

Industrial crops and products, 2020-12, Vol.158, p.112776, Article 112776

2020

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PO-03-200 THE RESPONSE TO AJMALINE PROVOCATION IN HEALTHY SUBJECTS

Heart rhythm, 2023-05, Vol.20 (5), p.S399-S400

2023

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AJM300, a novel oral antagonist of α4‐integrin, sustains an increase in circulating lymphocytes: A randomised controlled trial in healthy male subjects

British journal of clinical pharmacology, 2020-03, Vol.86 (3), p.591-600

2020

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Ajmalicine induces the pyroptosis of hepatoma cells to exert the antitumor effect

Journal of biochemical and molecular toxicology, 2024-01, Vol.38 (1), p.e23614-n/a

2024

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Ajmalicine and its Analogues Against AChE and BuChE for the Management of Alzheimer's Disease: An In-silico Study

Current pharmaceutical design, 2020-01, Vol.26 (37), p.4808

2020

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Nine year experience of the Northern Ireland Inherited Cardiac Conditions Service (NI ICC of slow vs. rapid ajmaline infusion protocols for the diagnosis of Brugada syndrome (BrS)

European heart journal, 2021-10, Vol.42 (Supplement_1)

2021

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Effects of β-cyclodextrin and methyl jasmonate on the production of vindoline, catharanthine, and ajmalicine in Catharanthus roseus cambial meristematic cell cultures

Applied microbiology and biotechnology, 2015-09, Vol.99 (17), p.7035-7045

2015

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Vitamin D supplementation in obese type 2 diabetes subjects in Ajman, UAE: a randomized controlled double-blinded clinical trial

European journal of clinical nutrition, 2015-06, Vol.69 (6), p.707-711

2015

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Simultaneous activation of the small conductance calcium-activated potassium current by acetylcholine and inhibition of sodium current by ajmaline cause J-wave syndrome in Langendorff-perfused rabbit ventricles

Heart rhythm, 2021-01, Vol.18 (1), p.98-108

2021

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Imaging in the European Heart Journal: the team of Deputy and Associate Editors Chiara Bucciarelli-Ducci, João L. Cavalcante, and Nina Ajmone-Marsan

European heart journal, 2021-06, Vol.42 (24), p.2326-2326

Liberale, Luca

2021

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Structure units oriented approach towards collective synthesis of sarpagine-ajmaline-koumine type alkaloids

Safety and Efficacy of AJM300, an Oral Antagonist of α4 Integrin, in Induction Therapy for Patients With Active Ulcerative Colitis

Construction of ajmalicine and sanguinarine de novo biosynthetic pathways using stable integration sites in yeast

Endophytes enhance the production of root alkaloids ajmalicine and serpentine by modulating the terpenoid indole alkaloid pathway in Catharanthus roseus roots

Discovery of Unusual Ajmaline‐Macroline Type Bisindole Alkaloids from Alstonia macrophylla by Building Blocks‐Based Molecular Networking

De novo biosynthesis of antiarrhythmic alkaloid ajmaline

Modulation of terpenoid indole alkaloid pathway via elicitation with phytosynthesized silver nanoparticles for the enhancement of ajmalicine, a pharmaceutically important alkaloid

dST-Tiso Interval, a Novel Electrocardiographic Marker of Ventricular Arrhythmia Inducibility in Individuals With Ajmaline-Induced Brugada Type I Pattern

Predicting ventricular arrhythmia inducibility in ajmaline-induced brugada type I pattern: validation of the dST-Tiso interval

Ajmalicine and Reserpine: Indole Alkaloids as Multi-Target Directed Ligands Towards Factors Implicated in Alzheimer's Disease

Impact of SMART Pass filter in patients with ajmaline-induced Brugada syndrome and subcutaneous implantable cardioverter-defibrillator eligibility failure: results from a prospective multicentre study

Methylobacterium ajmalii sp. nov., Isolated From the International Space Station

Ajmaline Testing and the Brugada Syndrome

Local depolarization abnormalities are the dominant pathophysiologic mechanism for type 1 electrocardiogram in brugada syndrome a study of electrocardiograms, vectorcardiograms, and body surface potential maps during ajmaline provocation

AJM300 (carotegrast methyl), an oral antagonist of α4-integrin, as induction therapy for patients with moderately active ulcerative colitis: a multicentre, randomised, double-blind, placebo-controlled, phase 3 study

Accumulation of ajmalicine and vinblastine in cell cultures is enhanced by endophytic fungi of Catharanthus roseus cv. Icy Pink

PO-03-200 THE RESPONSE TO AJMALINE PROVOCATION IN HEALTHY SUBJECTS

AJM300, a novel oral antagonist of α4‐integrin, sustains an increase in circulating lymphocytes: A randomised controlled trial in healthy male subjects

Ajmalicine induces the pyroptosis of hepatoma cells to exert the antitumor effect

Ajmalicine and its Analogues Against AChE and BuChE for the Management of Alzheimer's Disease: An In-silico Study

Nine year experience of the Northern Ireland Inherited Cardiac Conditions Service (NI ICC of slow vs. rapid ajmaline infusion protocols for the diagnosis of Brugada syndrome (BrS)

Effects of β-cyclodextrin and methyl jasmonate on the production of vindoline, catharanthine, and ajmalicine in Catharanthus roseus cambial meristematic cell cultures

Vitamin D supplementation in obese type 2 diabetes subjects in Ajman, UAE: a randomized controlled double-blinded clinical trial

Simultaneous activation of the small conductance calcium-activated potassium current by acetylcholine and inhibition of sodium current by ajmaline cause J-wave syndrome in Langendorff-perfused rabbit ventricles

Imaging in the European Heart Journal: the team of Deputy and Associate Editors Chiara Bucciarelli-Ducci, João L. Cavalcante, and Nina Ajmone-Marsan

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