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Multiple biological functions of Twist1 in various cancers

Oncotarget, 2017-03, Vol.8 (12), p.20380-20393

2017

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Prenatal co-exposure to diisodecyl phthalate and ozone contribute to depressive behavior in offspring mice through oxidative stress and TWIST1 participation

The Science of the total environment, 2024-06, Vol.928, p.172411-172411, Article 172411

2024

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Loss of Twist1 and balanced retinoic acid signaling from the meninges causes cortical folding in mice

Development (Cambridge), 2023-09, Vol.150 (18)

2023

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Anti-migration and anti-invasion effects of LY-290181 on breast cancer cell lines through the inhibition of Twist1

BMB reports, 2023-07, Vol.56 (7), p.410-415

2023

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Elevated TWIST1 expression in myelodysplastic syndromes/ acute myeloid leukemia reduces efficacy of hypomethylating therapy with decitabine

Haematologica (Roma), 2020-01, Vol.105 (10), p.e502

2020

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Deregulation of TWIST1 expression by promoter methylation in gastrointestinal cancers

Saudi journal of biological sciences, 2024, p.103842, Article 103842

Alfahed, Abdulaziz

2024

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M7824, a novel bifunctional anti-PD-L1/TGFβ Trap fusion protein, promotes anti-tumor efficacy as monotherapy and in combination with vaccine

Oncoimmunology, 2018-05, Vol.7 (5), p.e1426519-e1426519

2018

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E3 ubiquitin ligase RBX1 drives the metastasis of triple negative breast cancer through a FBXO45-TWIST1-dependent degradation mechanism

Aging (Albany, NY.), 2022-07, Vol.14 (13), p.5493-5510

2022

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Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis

Cancer cell, 2017-02, Vol.31 (2), p.286-299

2017

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S100A16 induces epithelial-mesenchymal transition in human PDAC cells and is a new therapeutic target for pancreatic cancer treatment that synergizes with gemcitabine

Biochemical pharmacology, 2021-07, Vol.189, p.114396-114396, Article 114396

2021

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In vitro and in vivo anti-tumor activity of Coenzyme Q0 against TWIST1-overexpressing HNSCC cells: ROS-mediated inhibition of EMT/metastasis and autophagy/apoptosis induction

Toxicology and applied pharmacology, 2023-04, Vol.465, p.116453-116453, Article 116453

2023

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CPEB1 orchestrates a fine-tuning of miR-145-5p tumor-suppressive activity on TWIST1 translation in prostate cancer cells

Oncotarget, 2020-11, Vol.11 (45), p.4155-4168

2020

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Quercetin restrains TGF-β1-induced epithelial–mesenchymal transition by inhibiting Twist1 and regulating E-cadherin expression

Biochemical and biophysical research communications, 2018-03, Vol.498 (1), p.132-138

2018

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Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex

Developmental cell, 2020-08, Vol.54 (3), p.302-316.e7

2020

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TWIST1 rescue calcium overload and apoptosis induced by inflammatory microenvironment in S. aureus-induced osteomyelitis

International immunopharmacology, 2023-06, Vol.119, p.110153-110153, Article 110153

2023

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TWIST1 Alleviates Hypoxia-induced Damage of Trophoblast Cells by inhibiting mitochondrial apoptosis pathway

Experimental cell research, 2019-12, Vol.385 (2), p.111687-111687, Article 111687

2019

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Linkage between EMT and stemness state through molecular association between TWIST1 and NY-ESO1 in esophageal squamous cell carcinoma

Biochimie, 2019-08, Vol.163, p.84-93

2019

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lncRNA JPX/miR-33a-5p/Twist1 axis regulates tumorigenesis and metastasis of lung cancer by activating Wnt/β-catenin signaling

Molecular cancer, 2020-01, Vol.19 (1), p.9-9, Article 9

2020

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Endothelial-to-Mesenchymal Transition in Pulmonary Hypertension

Circulation (New York, N.Y.), 2015-03, Vol.131 (11), p.1006-1018

2015

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Knockdown of MKL1 ameliorates oxidative stress-induced chondrocyte apoptosis and cartilage matrix degeneration by activating TWIST1-mediated PI3K/AKT signaling pathway in rats

Autoimmunity (Chur, Switzerland), 2022-11, Vol.55 (8), p.559-566

2022

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Improvement of histone deacetylase inhibitor efficacy by SN38 through TWIST1 suppression in synovial sarcoma

Cancer innovation (Print), 2024-04, Vol.3 (2), p.n/a

2024

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Cranial Suture Regeneration Mitigates Skull and Neurocognitive Defects in Craniosynostosis

Cell, 2021-01, Vol.184 (1), p.243-256.e18

2021

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ING1 inhibits Twist1 expression to block EMT and is antagonized by the HDAC inhibitor vorinostat

European journal of cell biology, 2023-09, Vol.102 (3), p.151341-151341, Article 151341

2023

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Anti-angiogenic treatment promotes triple-negative breast cancer invasion via vasculogenic mimicry

Cancer biology & therapy, 2017-04, Vol.18 (4), p.205-213

2017

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Multiple biological functions of Twist1 in various cancers

Prenatal co-exposure to diisodecyl phthalate and ozone contribute to depressive behavior in offspring mice through oxidative stress and TWIST1 participation

Loss of Twist1 and balanced retinoic acid signaling from the meninges causes cortical folding in mice

Anti-migration and anti-invasion effects of LY-290181 on breast cancer cell lines through the inhibition of Twist1

Elevated TWIST1 expression in myelodysplastic syndromes/ acute myeloid leukemia reduces efficacy of hypomethylating therapy with decitabine

Deregulation of TWIST1 expression by promoter methylation in gastrointestinal cancers

M7824, a novel bifunctional anti-PD-L1/TGFβ Trap fusion protein, promotes anti-tumor efficacy as monotherapy and in combination with vaccine

E3 ubiquitin ligase RBX1 drives the metastasis of triple negative breast cancer through a FBXO45-TWIST1-dependent degradation mechanism

Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis

S100A16 induces epithelial-mesenchymal transition in human PDAC cells and is a new therapeutic target for pancreatic cancer treatment that synergizes with gemcitabine

In vitro and in vivo anti-tumor activity of Coenzyme Q0 against TWIST1-overexpressing HNSCC cells: ROS-mediated inhibition of EMT/metastasis and autophagy/apoptosis induction

CPEB1 orchestrates a fine-tuning of miR-145-5p tumor-suppressive activity on TWIST1 translation in prostate cancer cells

Quercetin restrains TGF-β1-induced epithelial–mesenchymal transition by inhibiting Twist1 and regulating E-cadherin expression

Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex

TWIST1 rescue calcium overload and apoptosis induced by inflammatory microenvironment in S. aureus-induced osteomyelitis

LGR5 expressing skin fibroblasts define a major cellular hub perturbed in scleroderma

TWIST1 Alleviates Hypoxia-induced Damage of Trophoblast Cells by inhibiting mitochondrial apoptosis pathway

Linkage between EMT and stemness state through molecular association between TWIST1 and NY-ESO1 in esophageal squamous cell carcinoma

lncRNA JPX/miR-33a-5p/Twist1 axis regulates tumorigenesis and metastasis of lung cancer by activating Wnt/β-catenin signaling

Endothelial-to-Mesenchymal Transition in Pulmonary Hypertension

Knockdown of MKL1 ameliorates oxidative stress-induced chondrocyte apoptosis and cartilage matrix degeneration by activating TWIST1-mediated PI3K/AKT signaling pathway in rats

Improvement of histone deacetylase inhibitor efficacy by SN38 through TWIST1 suppression in synovial sarcoma

Cranial Suture Regeneration Mitigates Skull and Neurocognitive Defects in Craniosynostosis

ING1 inhibits Twist1 expression to block EMT and is antagonized by the HDAC inhibitor vorinostat

Anti-angiogenic treatment promotes triple-negative breast cancer invasion via vasculogenic mimicry

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