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P-Glycoprotein: One Mechanism, Many Tasks and the Consequences for Pharmacotherapy of Cancers

Frontiers in oncology, 2020-10, Vol.10, p.576559-576559

Seelig, Anna

2020

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Chemical molecular‐based approach to overcome multidrug resistance in cancer by targeting P‐glycoprotein (P‐gp)

Medicinal research reviews, 2021-01, Vol.41 (1), p.525-555

2021

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Rutin, a Quercetin Glycoside, Restores Chemosensitivity in Human Breast Cancer Cells

Phytotherapy research, 2017-10, Vol.31 (10), p.1529-1538

2017

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Modulation of expression/function of intestinal P-glycoprotein under disease states

Expert opinion on drug metabolism & toxicology, 2020-01, Vol.16 (1), p.59-78

2020

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Intestinal P‐glycoprotein inhibitors, benzoxanthone analogues

Journal of pharmacy and pharmacology, 2018-02, Vol.70 (2), p.234-241

2018

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Natural Products as Alternative Choices for P-Glycoprotein (P-gp) Inhibition

Molecules (Basel, Switzerland), 2017-05, Vol.22 (6), p.871

2017

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Impact of P‐glycoprotein and/or CYP3A4‐interacting drugs on effectiveness and safety of non‐vitamin K antagonist oral anticoagulants in patients with atrial fibrillation: A meta‐analysis

British journal of clinical pharmacology, 2022-07, Vol.88 (7), p.3039-3051

2022

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P‐glycoprotein: a role in the export of amyloid‐β in Alzheimer's disease?

The FEBS journal, 2020-02, Vol.287 (4), p.612-625

2020

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Structure-activity relationship and mechanism of flavonoids on the inhibitory activity of P-glycoprotein (P-gp)-mediated transport of rhodamine123 and daunorubicin in P-gp overexpressed human mouth epidermal carcinoma (KB/MDR) cells

Food and chemical toxicology, 2021-09, Vol.155, p.112381-112381, Article 112381

2021

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Probing the Mechanisms Underlying the Transport of the Vinca Alkaloids by P-glycoprotein

Journal of pharmaceutical sciences, 2024-03

2024

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Refined structures of mouse P‐glycoprotein

Protein science, 2014-01, Vol.23 (1), p.34-46

2014

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Long acting tariquidar loaded stearic acid-modified hydroxyapatite enhances brain penetration and antitumor effect of temozolomide

European journal of pharmaceutics and biopharmaceutics, 2024-04, Vol.197, p.114231-114231, Article 114231

2024

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P-glycoprotein Inhibition for Optimal Drug Delivery

Drug Target Insights, 2013-08, Vol.2013 (2013), p.27-34

Amin, Md. Lutful

2013

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Trivariate Linear Regression and Machine Learning Prediction of Possible Roles of Efflux Transporters in Estimated Intestinal Permeability Values of 301 Disparate Chemicals

Biological and Pharmaceutical Bulletin, 2022, pp.b22-00221

2022

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Effects of Hypericum perforatum (St John's wort) on the pharmacokinetics and pharmacodynamics of rivaroxaban in humans

British journal of clinical pharmacology, 2021-03, Vol.87 (3), p.1466-1474

2021

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Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein

Acta crystallographica. Section D, Biological crystallography., 2015-03, Vol.71 (3), p.732-741

2015

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Evaluation of the effect of P‐glycoprotein inhibition and induction on talazoparib disposition in patients with advanced solid tumours

British journal of clinical pharmacology, 2020-04, Vol.86 (4), p.771-778

2020

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Structural, Molecular, and Functional Alterations of the Blood-Brain Barrier during Epileptogenesis and Epilepsy: A Cause, Consequence, or Both?

International journal of molecular sciences, 2020-01, Vol.21 (2), p.591

2020

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Drug resistance in multiple myeloma

Cancer treatment reviews, 2018-11, Vol.70, p.199-208

2018

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Select Drug-Drug Interactions With Direct Oral Anticoagulants

Journal of the American College of Cardiology, 2020-03, Vol.75 (11), p.1341-1350

2020

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Cytosolic phospholipase A2 is a key regulator of blood‐brain barrier function in epilepsy

The FASEB journal, 2019-12, Vol.33 (12), p.14281-14295

2019

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The MDR1 (ABCB1) gene polymorphism and its clinical implications

Clinical pharmacokinetics, 2004-01, Vol.43 (9), p.553-576

2004

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Isobavachalcone as an Active Membrane Perturbing Agent and Inhibitor of ABCB1 Multidrug Transporter

Molecules (Basel, Switzerland), 2021-07, Vol.26 (15), p.4637

2021

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Altered blood–brain barrier and blood–spinal cord barrier dynamics in amyotrophic lateral sclerosis: Impact on medication efficacy and safety

British journal of pharmacology, 2022-06, Vol.179 (11), p.2577-2588

2022

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Quantitative Atlas of Blood–Brain Barrier Transporters, Receptors, and Tight Junction Proteins in Rats and Common Marmoset

Journal of pharmaceutical sciences, 2013-09, Vol.102 (9), p.3343-3355

2013

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P-Glycoprotein: One Mechanism, Many Tasks and the Consequences for Pharmacotherapy of Cancers

Chemical molecular‐based approach to overcome multidrug resistance in cancer by targeting P‐glycoprotein (P‐gp)

Rutin, a Quercetin Glycoside, Restores Chemosensitivity in Human Breast Cancer Cells

Modulation of expression/function of intestinal P-glycoprotein under disease states

Intestinal P‐glycoprotein inhibitors, benzoxanthone analogues

Natural Products as Alternative Choices for P-Glycoprotein (P-gp) Inhibition

Impact of P‐glycoprotein and/or CYP3A4‐interacting drugs on effectiveness and safety of non‐vitamin K antagonist oral anticoagulants in patients with atrial fibrillation: A meta‐analysis

P‐glycoprotein: a role in the export of amyloid‐β in Alzheimer's disease?

Structure-activity relationship and mechanism of flavonoids on the inhibitory activity of P-glycoprotein (P-gp)-mediated transport of rhodamine123 and daunorubicin in P-gp overexpressed human mouth epidermal carcinoma (KB/MDR) cells

Probing the Mechanisms Underlying the Transport of the Vinca Alkaloids by P-glycoprotein

Refined structures of mouse P‐glycoprotein

Long acting tariquidar loaded stearic acid-modified hydroxyapatite enhances brain penetration and antitumor effect of temozolomide

P-glycoprotein Inhibition for Optimal Drug Delivery

Trivariate Linear Regression and Machine Learning Prediction of Possible Roles of Efflux Transporters in Estimated Intestinal Permeability Values of 301 Disparate Chemicals

Effects of Hypericum perforatum (St John's wort) on the pharmacokinetics and pharmacodynamics of rivaroxaban in humans

Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein

Evaluation of the effect of P‐glycoprotein inhibition and induction on talazoparib disposition in patients with advanced solid tumours

Structural, Molecular, and Functional Alterations of the Blood-Brain Barrier during Epileptogenesis and Epilepsy: A Cause, Consequence, or Both?

Drug resistance in multiple myeloma

Select Drug-Drug Interactions With Direct Oral Anticoagulants

Cytosolic phospholipase A2 is a key regulator of blood‐brain barrier function in epilepsy

The MDR1 (ABCB1) gene polymorphism and its clinical implications

Isobavachalcone as an Active Membrane Perturbing Agent and Inhibitor of ABCB1 Multidrug Transporter

Altered blood–brain barrier and blood–spinal cord barrier dynamics in amyotrophic lateral sclerosis: Impact on medication efficacy and safety

Quantitative Atlas of Blood–Brain Barrier Transporters, Receptors, and Tight Junction Proteins in Rats and Common Marmoset

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