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The Role of Nitroglycerin and Other Nitrogen Oxides in Cardiovascular Therapeutics

Journal of the American College of Cardiology, 2017-11, Vol.70 (19), p.2393-2410

2017

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Biotransformation of organic nitrates by glutathione S-transferases and other enzymes: An appraisal of the pioneering work by William B. Jakoby

Analytical biochemistry, 2022-05, Vol.644, p.113993, Article 113993

2022

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The status of knowledge on migraines: The role of microglia

Journal of neuroimmunology, 2023-08, Vol.381, p.578118-578118, Article 578118

2023

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Gastrodin alleviates NTG-induced migraine-like pain via inhibiting succinate/HIF-1α/TRPM2 signaling pathway in trigeminal ganglion

Phytomedicine (Stuttgart), 2024-03, Vol.125, p.155266-155266, Article 155266

2024

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The enigma of nitroglycerin bioactivation and nitrate tolerance: news, views and troubles

British journal of pharmacology, 2008-09, Vol.155 (2), p.170-184

2008

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Relation of mitochondrial oxygen consumption in peripheral blood mononuclear cells to vascular function in type 2 diabetes mellitus

Vascular medicine (London, England), 2014-02, Vol.19 (1), p.67-74

2014

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Chemosensitization of Cancer In vitro and In vivo by Nitric Oxide Signaling

Clinical cancer research, 2007-04, Vol.13 (7), p.2199-2206

2007

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An Essential Role for Mitochondrial Aldehyde Dehydrogenase in Nitroglycerin Bioactivation

Proceedings of the National Academy of Sciences - PNAS, 2005-08, Vol.102 (34), p.12159-12164

2005

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Vascular Bioactivation of Nitroglycerin Is Catalyzed by Cytosolic Aldehyde Dehydrogenase-2

Circulation research, 2012-02, Vol.110 (3), p.385-393

2012

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In focus in HCB

Histochemistry and cell biology, 2019-10, Vol.152 (4), p.249-251

2019

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Sustained Formation of Nitroglycerin-Derived Nitric Oxide by Aldehyde Dehydrogenase-2 in Vascular Smooth Muscle without Added Reductants: Implications for the Development of Nitrate Tolerance

Molecular pharmacology, 2018-04, Vol.93 (4), p.335

2018

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Role of Mitochondrial Aldehyde Dehydrogenase in Nitroglycerin-Mediated Vasodilation: Observations Concerning the Dose-Response Relationship

Journal of cardiovascular pharmacology, 2019-06, Vol.73 (6), p.359-364

2019

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Mitochondrial aldehyde dehydrogenase-2 (ALDH2) Glu504Lys polymorphism contributes to the variation in efficacy of sublingual nitroglycerin

The Journal of clinical investigation, 2006-02, Vol.116 (2), p.506-511

2006

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Nitric oxide as a unique signaling molecule in the vascular system: a historical overview

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2002-12, Vol.53 (4 Pt 1), p.503-514

Ignarro, L J

2002

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Normalization of hemoglobin-based oxygen carrier-201 induced vasoconstriction: targeting nitric oxide and endothelin

Journal of applied physiology (1985), 2017-05, Vol.122 (5), p.1227-1237

2017

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Impact of chronic congestive heart failure on pharmacokinetics and vasomotor effects of infused nitrite

British journal of pharmacology, 2013-06, Vol.169 (3), p.659-670

2013

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Vascular bioactivation of nitroglycerin by aldehyde dehydrogenase-2: reaction intermediates revealed by crystallography and mass spectrometry

The Journal of biological chemistry, 2012-11, Vol.287 (45), p.38124-38134

2012

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Catalysis of nitrite generation from nitroglycerin by glyceraldehyde-3-phosphate dehydrogenase (GAPDH)

Nitric oxide, 2013-11, Vol.35, p.116-122

2013

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Stable isotope-assisted LC⿿MS/MS monitoring of glyceryl trinitrate bioactivation in a cell culture model of nitrate tolerance

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016-04, Vol.1019, p.156-163

2016

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Quercetin and its major metabolites selectively modulate cyclic GMP‐dependent relaxations and associated tolerance in pig isolated coronary artery

British journal of pharmacology, 2010-02, Vol.159 (3), p.566-575

2010

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Characterization of the East Asian Variant of Aldehyde Dehydrogenase-2: BIOACTIVATION OF NITROGLYCERIN AND EFFECTS OF Alda-1

The Journal of biological chemistry, 2010-01, Vol.285 (2), p.943-952

2010

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Effects of Nitroglycerine on Renal Ischemia-Reperfusion Injury in Adult Male Rats

Drug research, 2019-10, Vol.69 (11), p.612-620

2019

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Reversal of mitochondrial dysfunction by coenzyme Q10 supplement improves endothelial function in patients with ischaemic left ventricular systolic dysfunction: A randomized controlled trial

Atherosclerosis, 2011-06, Vol.216 (2), p.395-401

2011

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Enhancement of Tumor-Targeted Delivery of Bacteria with Nitroglycerin Involving Augmentation of the EPR Effect

Methods in molecular biology (Clifton, N.J.), 2016-01, Vol.1409, p.9

2016

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Structural and functional consequences of coenzyme binding to the inactive asian variant of mitochondrial aldehyde dehydrogenase: roles of residues 475 and 487

The Journal of biological chemistry, 2007-04, Vol.282 (17), p.12940-12950

2007

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The Role of Nitroglycerin and Other Nitrogen Oxides in Cardiovascular Therapeutics

Biotransformation of organic nitrates by glutathione S-transferases and other enzymes: An appraisal of the pioneering work by William B. Jakoby

The status of knowledge on migraines: The role of microglia

Gastrodin alleviates NTG-induced migraine-like pain via inhibiting succinate/HIF-1α/TRPM2 signaling pathway in trigeminal ganglion

The enigma of nitroglycerin bioactivation and nitrate tolerance: news, views and troubles

Relation of mitochondrial oxygen consumption in peripheral blood mononuclear cells to vascular function in type 2 diabetes mellitus

Chemosensitization of Cancer In vitro and In vivo by Nitric Oxide Signaling

An Essential Role for Mitochondrial Aldehyde Dehydrogenase in Nitroglycerin Bioactivation

Vascular Bioactivation of Nitroglycerin Is Catalyzed by Cytosolic Aldehyde Dehydrogenase-2

In focus in HCB

Sustained Formation of Nitroglycerin-Derived Nitric Oxide by Aldehyde Dehydrogenase-2 in Vascular Smooth Muscle without Added Reductants: Implications for the Development of Nitrate Tolerance

Role of Mitochondrial Aldehyde Dehydrogenase in Nitroglycerin-Mediated Vasodilation: Observations Concerning the Dose-Response Relationship

Mitochondrial aldehyde dehydrogenase-2 (ALDH2) Glu504Lys polymorphism contributes to the variation in efficacy of sublingual nitroglycerin

Nitric oxide as a unique signaling molecule in the vascular system: a historical overview

Normalization of hemoglobin-based oxygen carrier-201 induced vasoconstriction: targeting nitric oxide and endothelin

Impact of chronic congestive heart failure on pharmacokinetics and vasomotor effects of infused nitrite

Vascular bioactivation of nitroglycerin by aldehyde dehydrogenase-2: reaction intermediates revealed by crystallography and mass spectrometry

Catalysis of nitrite generation from nitroglycerin by glyceraldehyde-3-phosphate dehydrogenase (GAPDH)

Stable isotope-assisted LC⿿MS/MS monitoring of glyceryl trinitrate bioactivation in a cell culture model of nitrate tolerance

Quercetin and its major metabolites selectively modulate cyclic GMP‐dependent relaxations and associated tolerance in pig isolated coronary artery

Characterization of the East Asian Variant of Aldehyde Dehydrogenase-2: BIOACTIVATION OF NITROGLYCERIN AND EFFECTS OF Alda-1

Effects of Nitroglycerine on Renal Ischemia-Reperfusion Injury in Adult Male Rats

Reversal of mitochondrial dysfunction by coenzyme Q10 supplement improves endothelial function in patients with ischaemic left ventricular systolic dysfunction: A randomized controlled trial

Enhancement of Tumor-Targeted Delivery of Bacteria with Nitroglycerin Involving Augmentation of the EPR Effect

Structural and functional consequences of coenzyme binding to the inactive asian variant of mitochondrial aldehyde dehydrogenase: roles of residues 475 and 487

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