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The MYPT2-regulated striated muscle-specific myosin light chain phosphatase limits cardiac myosin phosphorylation in vivo

The Journal of biological chemistry, 2024-02, Vol.300 (2), p.105652-105652, Article 105652

2024

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Phosphatase regulatory subunit MYPT2 knockout partially compensates for the cardiac dysfunction in mice caused by lack of myosin light chain kinase 3

The Journal of biological chemistry, 2023-04, Vol.299 (4), p.104584-104584, Article 104584

2023

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Constitutive Phosphorylation of Cardiac Myosin Regulatory Light Chain in Vivo

The Journal of biological chemistry, 2015-04, Vol.290 (17), p.10703-10716

2015

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Role of myosin light chain phosphatase in cardiac physiology and pathophysiology

Journal of molecular and cellular cardiology, 2016-12, Vol.101, p.35-43

2016

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Functional and Molecular Characterisation of Heart Failure Progression in Mice and the Role of Myosin Regulatory Light Chains in the Recovery of Cardiac Muscle Function

International journal of molecular sciences, 2021-12, Vol.23 (1), p.88

2021

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The significance of regulatory light chain phosphorylation in cardiac physiology

Archives of biochemistry and biophysics, 2011-06, Vol.510 (2), p.129-134

2011

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Regulation of myosin II during cytokinesis in higher eukaryotes

Trends in cell biology, 2005-07, Vol.15 (7), p.371-377

Matsumura, Fumio

2005

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Physiological signalling to myosin phosphatase targeting subunit‐1 phosphorylation in ileal smooth muscle

The Journal of physiology, 2016-06, Vol.594 (12), p.3209-3225

2016

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Blockade of ROCK inhibits migration of human primary keratinocytes and malignant epithelial skin cells by regulating actomyosin contractility

Scientific reports, 2019-12, Vol.9 (1), p.19930-13, Article 19930

2019

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Intracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis

Nature medicine, 2019-04, Vol.25 (4), p.690-700

2019

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Kindlin-2 regulates mesenchymal stem cell differentiation through control of YAP1/TAZ

The Journal of cell biology, 2018-04, Vol.217 (4), p.1431-1451

2018

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Myosin light chain kinase activation and calcium sensitization in smooth muscle in vivo

American Journal of Physiology: Cell Physiology, 2008-08, Vol.295 (2), p.C358-C364

2008

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A self-organized biomechanical network drives shape changes during tissue morphogenesis

Nature (London), 2015-08, Vol.524 (7565), p.351-355

2015

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Amelioration of IFN-γ and TNF-α-induced intestinal epithelial barrier dysfunction by berberine via suppression of MLCK-MLC phosphorylation signaling pathway

PloS one, 2013-05, Vol.8 (5), p.e61944

2013

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Sodium Butyrate Promotes Reassembly of Tight Junctions in Caco-2 Monolayers Involving Inhibition of MLCK/MLC2 Pathway and Phosphorylation of PKCβ2

International journal of molecular sciences, 2016-10, Vol.17 (10), p.1696

2016

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Getting the skinny on thick filament regulation in cardiac muscle biology and disease

Trends in cardiovascular medicine, 2014-05, Vol.24 (4), p.133-141

2014

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Pterostilbene Ameliorates DSS-Induced Intestinal Epithelial Barrier Loss in Mice via Suppression of the NF-κB-Mediated MLCK-MLC Signaling Pathway

Journal of agricultural and food chemistry, 2021-04, Vol.69 (13), p.3871-3878

2021

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Extracellular microvesicles and invadopodia mediate non-overlapping modes of tumor cell invasion

Scientific reports, 2015-10, Vol.5 (1), p.14748-14748, Article 14748

2015

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The suppression of myosin light chain (MLC) phosphorylation during the response to lipopolysaccharide (LPS): beneficial or detrimental to endothelial barrier?

Journal of cellular physiology, 2011-12, Vol.226 (12), p.3132-3146

2011

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Cardiac myosin regulatory light chain kinase modulates cardiac contractility by phosphorylating both myosin regulatory light chain and troponin I

The Journal of biological chemistry, 2020-04, Vol.295 (14), p.4398-4410

2020

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An association between NUAK2 and MRIP reveals a novel mechanism for regulation of actin stress fibers

Journal of cell science, 2011-02, Vol.124 (Pt 3), p.384-393

2011

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Atractylodes oil alleviates diarrhea-predominant irritable bowel syndrome by regulating intestinal inflammation and intestinal barrier via SCF/c-kit and MLCK/MLC2 pathways

Journal of ethnopharmacology, 2021-05, Vol.272, p.113925-113925, Article 113925

2021

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Dynamic myosin phosphorylation regulates contractile pulses and tissue integrity during epithelial morphogenesis

The Journal of cell biology, 2014-08, Vol.206 (3), p.435-450

2014

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Matrix metalloproteinase 9-induced increase in intestinal epithelial tight junction permeability contributes to the severity of experimental DSS colitis

American journal of physiology: Gastrointestinal and liver physiology, 2015-12, Vol.309 (12), p.G988-G997

2015

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The MYPT2-regulated striated muscle-specific myosin light chain phosphatase limits cardiac myosin phosphorylation in vivo

Phosphatase regulatory subunit MYPT2 knockout partially compensates for the cardiac dysfunction in mice caused by lack of myosin light chain kinase 3

Constitutive Phosphorylation of Cardiac Myosin Regulatory Light Chain in Vivo

Role of myosin light chain phosphatase in cardiac physiology and pathophysiology

Functional and Molecular Characterisation of Heart Failure Progression in Mice and the Role of Myosin Regulatory Light Chains in the Recovery of Cardiac Muscle Function

The significance of regulatory light chain phosphorylation in cardiac physiology

Regulation of myosin II during cytokinesis in higher eukaryotes

Physiological signalling to myosin phosphatase targeting subunit‐1 phosphorylation in ileal smooth muscle

Blockade of ROCK inhibits migration of human primary keratinocytes and malignant epithelial skin cells by regulating actomyosin contractility

Intracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis

Kindlin-2 regulates mesenchymal stem cell differentiation through control of YAP1/TAZ

Myosin light chain kinase activation and calcium sensitization in smooth muscle in vivo

A self-organized biomechanical network drives shape changes during tissue morphogenesis

Amelioration of IFN-γ and TNF-α-induced intestinal epithelial barrier dysfunction by berberine via suppression of MLCK-MLC phosphorylation signaling pathway

Sodium Butyrate Promotes Reassembly of Tight Junctions in Caco-2 Monolayers Involving Inhibition of MLCK/MLC2 Pathway and Phosphorylation of PKCβ2

Restoration of Cardiac Myosin Light Chain Kinase Ameliorates Systolic Dysfunction by Reducing Superrelaxed Myosin

Getting the skinny on thick filament regulation in cardiac muscle biology and disease

Pterostilbene Ameliorates DSS-Induced Intestinal Epithelial Barrier Loss in Mice via Suppression of the NF-κB-Mediated MLCK-MLC Signaling Pathway

Extracellular microvesicles and invadopodia mediate non-overlapping modes of tumor cell invasion

The suppression of myosin light chain (MLC) phosphorylation during the response to lipopolysaccharide (LPS): beneficial or detrimental to endothelial barrier?

Cardiac myosin regulatory light chain kinase modulates cardiac contractility by phosphorylating both myosin regulatory light chain and troponin I

An association between NUAK2 and MRIP reveals a novel mechanism for regulation of actin stress fibers

Atractylodes oil alleviates diarrhea-predominant irritable bowel syndrome by regulating intestinal inflammation and intestinal barrier via SCF/c-kit and MLCK/MLC2 pathways

Dynamic myosin phosphorylation regulates contractile pulses and tissue integrity during epithelial morphogenesis

Matrix metalloproteinase 9-induced increase in intestinal epithelial tight junction permeability contributes to the severity of experimental DSS colitis

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