UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist gegebenenfalls nur via VPN oder Shibboleth (DFN-AAI) möglich. mehr Informationen...

Transfer of benzo[a]pyrene from microplastics to Artemia nauplii and further to zebrafish via a trophic food web experiment: CYP1A induction and visual tracking of persistent organic pollutants

Environmental toxicology and chemistry, 2016-07, Vol.35 (7), p.1656-1666

2016

Link zum Volltext

Verfügbarkeit prüfen

Age‐ and Genotype‐Dependent Variability in the Protein Abundance and Activity of Six Major Uridine Diphosphate‐Glucuronosyltransferases in Human Liver

Clinical pharmacology and therapeutics, 2019-01, Vol.105 (1), p.131-141

2019

Link zum Volltext

Verfügbarkeit prüfen

Toxicity risk assessment of pyriproxyfen and metabolites in the rat liver: A vitro study

Journal of hazardous materials, 2020-05, Vol.389, p.121835, Article 121835

2020

Link zum Volltext

Verfügbarkeit prüfen

Discovery of Tropifexor (LJN452), a Highly Potent Non-bile Acid FXR Agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH)

Journal of medicinal chemistry, 2017-12, Vol.60 (24), p.9960-9973

2017

Link zum Volltext

Verfügbarkeit prüfen

Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors

Journal of medicinal chemistry, 2019-02, Vol.62 (3), p.1138-1166

2019

Link zum Volltext

Verfügbarkeit prüfen

Metabolite profiling and identification of enzymes responsible for the metabolism of mitragynine, the major alkaloid of Mitragyna speciosa (kratom)

Xenobiotica, 2019-11, Vol.49 (11), p.1279-1288

2019

Link zum Volltext

Verfügbarkeit prüfen

Discovery of Tyrosine Kinase 2 (TYK2) Inhibitor (PF-06826647) for the Treatment of Autoimmune Diseases

Journal of medicinal chemistry, 2020-11, Vol.63 (22), p.13561-13577

2020

Link zum Volltext

Verfügbarkeit prüfen

Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants

Drug metabolism and disposition, 2017-02, Vol.45 (2), p.216-223

2017

Link zum Volltext

Verfügbarkeit prüfen

Metabolic activation and drug-induced liver injury: in vitro approaches for the safety risk assessment of new drugs

Journal of applied toxicology, 2016-06, Vol.36 (6), p.752-768

2016

Link zum Volltext

Verfügbarkeit prüfen

Еvaluation of biocompatibility and antioxidant efficiency of chitosan-alginate nanoparticles loaded with quercetin

International journal of biological macromolecules, 2017-10, Vol.103, p.771-782

2017

Link zum Volltext

Verfügbarkeit prüfen

Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite

Drug metabolism and disposition, 2010-01, Vol.38 (1), p.92

2010

Link zum Volltext

Verfügbarkeit prüfen

Chemical composition and biological effects of kratom (Mitragyna speciosa): In vitro studies with implications for efficacy and drug interactions

Scientific reports, 2020-11, Vol.10 (1), p.19158, Article 19158

2020

Link zum Volltext

Verfügbarkeit prüfen

Tacrine–Trolox Hybrids: A Novel Class of Centrally Active, Nonhepatotoxic Multi-Target-Directed Ligands Exerting Anticholinesterase and Antioxidant Activities with Low In Vivo Toxicity

Journal of medicinal chemistry, 2015-11, Vol.58 (22), p.8985-9003

2015

Link zum Volltext

Verfügbarkeit prüfen

Jatrophane Diterpenoids as Modulators of P‑Glycoprotein-Dependent Multidrug Resistance (MDR): Advances of Structure–Activity Relationships and Discovery of Promising MDR Reversal Agents

Journal of medicinal chemistry, 2016-07, Vol.59 (13), p.6353-6369

2016

Link zum Volltext

Verfügbarkeit prüfen

Synthesis, Evaluation, and Mechanism Study of Novel Indole-Chalcone Derivatives Exerting Effective Antitumor Activity Through Microtubule Destabilization in Vitro and in Vivo

Journal of medicinal chemistry, 2016-06, Vol.59 (11), p.5264-5283

2016

Link zum Volltext

Verfügbarkeit prüfen

Drug interaction study of flavonoids toward CYP3A4 and their quantitative structure activity relationship (QSAR) analysis for predicting potential effects

Toxicology letters, 2018-09, Vol.294, p.27-36

2018

Link zum Volltext

Verfügbarkeit prüfen

Role of Inflammatory and Oxidative Stress, Cytochrome P450 2E1, and Bile Acid Disturbance in Rat Liver Injury Induced by Isoniazid and Lipopolysaccharide Cotreatment

Antimicrobial agents and chemotherapy, 2016-09, Vol.60 (9), p.5285-5293

2016

Link zum Volltext

Verfügbarkeit prüfen

Antioxidant and anti-inflammatory activities of six flavonoids separated from licorice

Food chemistry, 2013-11, Vol.141 (2), p.1063-1071

2013

Link zum Volltext

Verfügbarkeit prüfen

Inhibition of human UDP-glucuronosyltransferase enzymes by lapatinib, pazopanib, regorafenib and sorafenib: Implications for hyperbilirubinemia

Biochemical pharmacology, 2017-04, Vol.129, p.85-95

2017

Link zum Volltext

Verfügbarkeit prüfen

Role of the CLOCK protein in liver detoxification

British journal of pharmacology, 2019-12, Vol.176 (24), p.4639-4652

2019

Link zum Volltext

Verfügbarkeit prüfen

Discovery of Cytotoxic Dolastatin 10 Analogues with N‑Terminal Modifications

Journal of medicinal chemistry, 2014-12, Vol.57 (24), p.10527-10543

2014

Link zum Volltext

Verfügbarkeit prüfen

Effects of triazole fungicides on androgenic disruption and CYP3A4 enzyme activity

Environmental pollution (1987), 2017-03, Vol.222, p.504-512

2017

Link zum Volltext

Verfügbarkeit prüfen

Preclinical Evaluation of the Stability, Safety, and Efficacy of CD101, a Novel Echinocandin

Antimicrobial agents and chemotherapy, 2016-11, Vol.60 (11), p.6872-6879

2016

Link zum Volltext

Verfügbarkeit prüfen

Exploration of cytochrome P450 inhibition mediated drug-drug interaction potential of kratom alkaloids

Toxicology letters, 2020-02, Vol.319, p.148-154

2020

Link zum Volltext

Verfügbarkeit prüfen

Influence of metabolism on endocrine activities of bisphenol S

Chemosphere (Oxford), 2016-08, Vol.157, p.152-159

2016

Link zum Volltext

Verfügbarkeit prüfen

1 – 25 von 19.388

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(16.616)
Mit Volltextzugriff
(14.132)

Publikationsform

Sprache

15 weitere anzeigen...

Weniger anzeigen...

Erscheinungsjahr

n.n

Thema

Animals
(17.168)
Science & Technology
(14.141)
Life Sciences & Biomedicine
(13.878)
Rats
(12.913)
Male
(11.545)
Microsomes, Liver - Drug Effects
(11.109)
Microsomes, Liver - Metabolism
(9.471)
Microsomes, Liver - Enzymology
(8.917)
Pharmacology & Pharmacy
(6.824)
Biological And Medical Sciences
(6.814)
Medical Sciences
(5.524)
Humans
(4.891)
Toxicology
(4.746)
Cytochrome P-450 Enzyme System - Metabolism
(4.341)
Liver - Drug Effects
(3.867)
Female
(3.623)
In Vitro Techniques
(3.334)
Biochemistry & Molecular Biology
(3.327)
Mice
(3.161)
Kinetics
(2.995)

15 weitere anzeigen...

Weniger anzeigen...

Kollektion

IngentaConnect Journals
(8.672)
Elsevier Journal Backfiles on ScienceDirect (DFG Nationallizenzen)
(6.357)
Elsevier ScienceDirect Journals Complete
(6.051)
Ovid SocietyJournals and Single Titles
(5.643)
Free E-Journal (出版社公開部分のみ）
(5.601)
NUS Single-Journal Subscriptions
(2.687)
Wiley Online Library
(1.926)
IngentaConnect Journals
(1.332)
Wiley Online Library
(1.289)
SpringerNature Journals
(1.132)
Taylor & Francis E-Journals
(1.005)
Taylor & Francis
(989)
Oxford University Press Journals Current
(962)
SpringerLINK Contemporary (Konsortium Baden-Württemberg)
(869)
Oxford Journals 2020 Medicine
(707)
HEAL-Link subscriptions: Springer Book Series
(344)
Jstor Complete Legacy
(259)
Thieme - Connect here FIRST to enable access
(159)
SAGE Complete
(150)
Nature_系列刊
(137)

15 weitere anzeigen...

Weniger anzeigen...

Zeitschrift / Serie

5 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

Transfer of benzo[a]pyrene from microplastics to Artemia nauplii and further to zebrafish via a trophic food web experiment: CYP1A induction and visual tracking of persistent organic pollutants

Age‐ and Genotype‐Dependent Variability in the Protein Abundance and Activity of Six Major Uridine Diphosphate‐Glucuronosyltransferases in Human Liver

Toxicity risk assessment of pyriproxyfen and metabolites in the rat liver: A vitro study

Discovery of Tropifexor (LJN452), a Highly Potent Non-bile Acid FXR Agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH)

Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors

Metabolite profiling and identification of enzymes responsible for the metabolism of mitragynine, the major alkaloid of Mitragyna speciosa (kratom)

Discovery of Tyrosine Kinase 2 (TYK2) Inhibitor (PF-06826647) for the Treatment of Autoimmune Diseases

Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants

Metabolic activation and drug-induced liver injury: in vitro approaches for the safety risk assessment of new drugs

Еvaluation of biocompatibility and antioxidant efficiency of chitosan-alginate nanoparticles loaded with quercetin

Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite

Chemical composition and biological effects of kratom (Mitragyna speciosa): In vitro studies with implications for efficacy and drug interactions

Tacrine–Trolox Hybrids: A Novel Class of Centrally Active, Nonhepatotoxic Multi-Target-Directed Ligands Exerting Anticholinesterase and Antioxidant Activities with Low In Vivo Toxicity

Jatrophane Diterpenoids as Modulators of P‑Glycoprotein-Dependent Multidrug Resistance (MDR): Advances of Structure–Activity Relationships and Discovery of Promising MDR Reversal Agents

Synthesis, Evaluation, and Mechanism Study of Novel Indole-Chalcone Derivatives Exerting Effective Antitumor Activity Through Microtubule Destabilization in Vitro and in Vivo

Drug interaction study of flavonoids toward CYP3A4 and their quantitative structure activity relationship (QSAR) analysis for predicting potential effects

Role of Inflammatory and Oxidative Stress, Cytochrome P450 2E1, and Bile Acid Disturbance in Rat Liver Injury Induced by Isoniazid and Lipopolysaccharide Cotreatment

Antioxidant and anti-inflammatory activities of six flavonoids separated from licorice

Inhibition of human UDP-glucuronosyltransferase enzymes by lapatinib, pazopanib, regorafenib and sorafenib: Implications for hyperbilirubinemia

Role of the CLOCK protein in liver detoxification

Discovery of Cytotoxic Dolastatin 10 Analogues with N‑Terminal Modifications

Effects of triazole fungicides on androgenic disruption and CYP3A4 enzyme activity

Preclinical Evaluation of the Stability, Safety, and Efficacy of CD101, a Novel Echinocandin

Exploration of cytochrome P450 inhibition mediated drug-drug interaction potential of kratom alkaloids

Influence of metabolism on endocrine activities of bisphenol S

Suchergebnisse filtern