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Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy

Cancer cell, 2019-11, Vol.36 (5), p.483-497.e15

2019

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Myc proteins as therapeutic targets

Oncogene, 2010-03, Vol.29 (9), p.1249-1259

2010

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Tumor penetrating peptides inhibiting MYC as a potent targeted therapeutic strategy for triple-negative breast cancers

Oncogene, 2019-01, Vol.38 (1), p.140-150

2019

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Taking the Myc out of cancer: toward therapeutic strategies to directly inhibit c-Myc

Molecular cancer, 2021-01, Vol.20 (1), p.3-3, Article 3

2021

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N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer

Cancer cell, 2016-10, Vol.30 (4), p.563-577

2016

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Omomyc Reveals New Mechanisms To Inhibit the MYC Oncogene

Molecular and cellular biology, 2019-11, Vol.39 (22)

2019

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Deubiquitinating enzyme USP22 positively regulates c‐Myc stability and tumorigenic activity in mammalian and breast cancer cells

Journal of cellular physiology, 2017-12, Vol.232 (12), p.3664-3676

2017

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MYC and tumor metabolism: chicken and egg

The EMBO journal, 2017-12, Vol.36 (23), p.3409-3420

2017

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Diagnostic and prognostic value of c-MYC gene expression in hematological malignancies

African health sciences, 2023-06, Vol.23 (2), p.265-73

2023

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MYC as a target for cancer treatment

Cancer treatment reviews, 2021-03, Vol.94, p.102154-102154, Article 102154

2021

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Hepatitis C virus-induced activation of β-catenin promotes c-Myc expression and a cascade of pro-carcinogenetic events

Oncogene, 2013-09, Vol.32 (39), p.4683-4693

2013

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Circadian regulation of c-MYC in mice

Proceedings of the National Academy of Sciences - PNAS, 2020-09, Vol.117 (35), p.21609-21617

2020

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The histone deacetylase SIRT2 stabilizes Myc oncoproteins

Cell death and differentiation, 2013-03, Vol.20 (3), p.503-514

2013

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MYC, MYCL, and MYCN as therapeutic targets in lung cancer

Expert opinion on therapeutic targets, 2020-02, Vol.24 (2), p.101-114

2020

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OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors

Oncogene, 2017-04, Vol.36 (14), p.1911-1924

2017

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Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

Cell systems, 2018-03, Vol.6 (3), p.282-300.e2

2018

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Long noncoding RNA CCAT1, which could be activated by c-Myc, promotes the progression of gastric carcinoma

Journal of cancer research and clinical oncology, 2013-03, Vol.139 (3), p.437-445

2013

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Inhibition of Myc family proteins eradicates KRas-driven lung cancer in mice

Genes & development, 2013-03, Vol.27 (5), p.504-513

2013

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Mission Possible: Advances in MYC Therapeutic Targeting in Cancer

BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy, 2019-10, Vol.33 (5), p.539-553

2019

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Mitotic gene regulation by the N-MYC-WDR5-PDPK1 nexus

BMC genomics, 2024-04, Vol.25 (1), p.360-360

2024

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LINC01123, a c-Myc-activated long non-coding RNA, promotes proliferation and aerobic glycolysis of non-small cell lung cancer through miR-199a-5p/c-Myc axis

Journal of hematology and oncology, 2019-09, Vol.12 (1), p.91-91, Article 91

2019

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Blocking Myc to Treat Cancer: Reflecting on Two Decades of Omomyc

Cells (Basel, Switzerland), 2020-04, Vol.9 (4), p.883

2020

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Glucose Catabolism in Liver Tumors Induced by c-MYC Can Be Sustained by Various PKM1/PKM2 Ratios and Pyruvate Kinase Activities

Cancer research (Chicago, Ill.), 2017-08, Vol.77 (16), p.4355-4364

2017

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Intrinsic cell-penetrating activity propels Omomyc from proof of concept to viable anti-MYC therapy

Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy

Myc proteins as therapeutic targets

Tumor penetrating peptides inhibiting MYC as a potent targeted therapeutic strategy for triple-negative breast cancers

Taking the Myc out of cancer: toward therapeutic strategies to directly inhibit c-Myc

N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer

Omomyc Reveals New Mechanisms To Inhibit the MYC Oncogene

Deubiquitinating enzyme USP22 positively regulates c‐Myc stability and tumorigenic activity in mammalian and breast cancer cells

MYC and tumor metabolism: chicken and egg

Diagnostic and prognostic value of c-MYC gene expression in hematological malignancies

MYC as a target for cancer treatment

Hepatitis C virus-induced activation of β-catenin promotes c-Myc expression and a cascade of pro-carcinogenetic events

Circadian regulation of c-MYC in mice

The histone deacetylase SIRT2 stabilizes Myc oncoproteins

MYC, MYCL, and MYCN as therapeutic targets in lung cancer

OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors

Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

Long noncoding RNA CCAT1, which could be activated by c-Myc, promotes the progression of gastric carcinoma

Inhibition of Myc family proteins eradicates KRas-driven lung cancer in mice

Mission Possible: Advances in MYC Therapeutic Targeting in Cancer

Mitotic gene regulation by the N-MYC-WDR5-PDPK1 nexus

LINC01123, a c-Myc-activated long non-coding RNA, promotes proliferation and aerobic glycolysis of non-small cell lung cancer through miR-199a-5p/c-Myc axis

Blocking Myc to Treat Cancer: Reflecting on Two Decades of Omomyc

Glucose Catabolism in Liver Tumors Induced by c-MYC Can Be Sustained by Various PKM1/PKM2 Ratios and Pyruvate Kinase Activities

C‐MYC–positive relapsed and refractory, diffuse large B‐cell lymphoma: Impact of additional “hits” and outcomes with subsequent therapy

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