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The structural pathway of interleukin 1 (IL-1) initiated signaling reveals mechanisms of oncogenic mutations and SNPs in inflammation and cancer

PLoS computational biology, 2014-02, Vol.10 (2), p.e1003470

2014

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Arrestin-3 Binds c-Jun N-terminal Kinase 1 (JNK1) and JNK2 and Facilitates the Activation of These Ubiquitous JNK Isoforms in Cells via Scaffolding

The Journal of biological chemistry, 2013-12, Vol.288 (52), p.37332-37342

2013

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Mitogen-Activated Protein Kinase Cascade MKK7-MPK6 Plays Important Roles in Plant Development and Regulates Shoot Branching by Phosphorylating PIN1 in Arabidopsis

PLoS biology, 2016-09, Vol.14 (9), p.e1002550-e1002550

2016

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Identification of a novel anoikis signalling pathway using the fungal virulence factor gliotoxin

Nature communications, 2018-08, Vol.9 (1), p.3524-14, Article 3524

2018

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Phosphatidic acid promotes the activation and plasma membrane localization of MKK7 and MKK9 in response to salt stress

Plant science (Limerick), 2019-10, Vol.287, p.110190-110190, Article 110190

2019

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Stress-Activated Protein Kinase JNK Modulates Depression-like Behaviors in Mice

Molecular neurobiology, 2023-05, Vol.60 (5), p.2367-2378

2023

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Role of the JIP4 Scaffold Protein in the Regulation of Mitogen-Activated Protein Kinase Signaling Pathways

Molecular and Cellular Biology, 2005-04, Vol.25 (7), p.2733-2743

2005

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A tumor-associated splice-isoform of MAP2K7 drives dedifferentiation in MBNL1-low cancers via JNK activation

Proceedings of the National Academy of Sciences - PNAS, 2020-07, Vol.117 (28), p.16391-16400

2020

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Anti-inflammatory Effects of Empagliflozin and Gemigliptin on LPS-Stimulated Macrophage via the IKK/NF-κB, MKK7/JNK, and JAK2/STAT1 Signalling Pathways

Journal of immunology research, 2021, Vol.2021, p.9944880-11

2021

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Mitogen Kinase Kinase (MKK7) Controls Cytokine Production In Vitro and In Vivo in Mice

International journal of molecular sciences, 2021-08, Vol.22 (17), p.9364

2021

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Activation of c-Jun N-terminal kinase (JNK) by widely used specific p38 MAPK inhibitors SB202190 and SB203580: A MLK-3-MKK7-dependent mechanism

Cellular signalling, 2008-04, Vol.20 (4), p.675-683

2008

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Loss of T Regulatory Cell Suppression following Signaling through Glucocorticoid-induced Tumor Necrosis Receptor (GITR) Is Dependent on c-Jun N-terminal Kinase Activation

The Journal of biological chemistry, 2012-05, Vol.287 (21), p.17100-17108

2012

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MKK3 was involved in larval settlement of the barnacle Amphibalanus amphitrite through activating the kinase activity of p38MAPK

PloS one, 2013-07, Vol.8 (7), p.e69510-e69510

2013

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Lycorine suppresses RANKL-induced osteoclastogenesis in vitro and prevents ovariectomy-induced osteoporosis and titanium particle-induced osteolysis in vivo

Scientific reports, 2015-08, Vol.5 (1), p.12853-12853, Article 12853

2015

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Scaffold Role of DUSP22 in ASK1-MKK7-JNK Signaling Pathway

PloS one, 2016-10, Vol.11 (10), p.e0164259-e0164259

2016

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Novel and Expanded Roles for MAPK Signaling in Arabidopsis Stomatal Cell Fate Revealed by Cell Type-Specific Manipulations

The Plant cell, 2009-11, Vol.21 (11), p.3506-3517

2009

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Arrestin-3 scaffolding of the JNK3 cascade suggests a mechanism for signal amplification

Proceedings of the National Academy of Sciences - PNAS, 2019-01, Vol.116 (3), p.810-815

2019

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Heme Oxygenase-1 Inhibits Neuronal Apoptosis in Spinal Cord Injury through Down-Regulation of Cdc42-MLK3-MKK7-JNK3 Axis

Journal of neurotrauma, 2017-02, Vol.34 (3), p.695

2017

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Tumor Progression Locus 2 in Hepatocytes Potentiates Both Liver and Systemic Metabolic Disorders in Mice

Hepatology (Baltimore, Md.), 2019-02, Vol.69 (2), p.524-544

2019

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Gq-Induced Apoptosis is Mediated by AKT Inhibition That Leads to PKC-Induced JNK Activation

Cellular physiology and biochemistry, 2018-10, Vol.50 (1), p.121-135

2018

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Calcium/Ask1/MKK7/JNK2/c-Src signalling cascade mediates disruption of intestinal epithelial tight junctions by dextran sulfate sodium

Biochemical journal, 2015-02, Vol.465 (3), p.503-515

2015

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Downregulated Gene Expression Spectrum and Immune Responses Changed During the Disease Progression in Patients With COVID-19

Clinical infectious diseases, 2020-11, Vol.71 (16), p.2052-2060

2020

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Structure and dynamics of the MKK7–JNK signaling complex

Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (11), p.3409-3414

2015

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Discovery of Turn-On Fluorescent Probes for Detecting PDEδ Protein in Living Cells and Tumor Slices

Analytical chemistry (Washington), 2020-07, Vol.92 (14), p.9516-9522

2020

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Manipulation of Mitogen-Activated Protein Kinase Kinase Signaling in the Arabidopsis Stomatal Lineage Reveals Motifs That Contribute to Protein Localization and Signaling Specificity

The Plant cell, 2014-08, Vol.26 (8), p.3358-3371

2014

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The structural pathway of interleukin 1 (IL-1) initiated signaling reveals mechanisms of oncogenic mutations and SNPs in inflammation and cancer

Arrestin-3 Binds c-Jun N-terminal Kinase 1 (JNK1) and JNK2 and Facilitates the Activation of These Ubiquitous JNK Isoforms in Cells via Scaffolding

Mitogen-Activated Protein Kinase Cascade MKK7-MPK6 Plays Important Roles in Plant Development and Regulates Shoot Branching by Phosphorylating PIN1 in Arabidopsis

Identification of a novel anoikis signalling pathway using the fungal virulence factor gliotoxin

Phosphatidic acid promotes the activation and plasma membrane localization of MKK7 and MKK9 in response to salt stress

Stress-Activated Protein Kinase JNK Modulates Depression-like Behaviors in Mice

Role of the JIP4 Scaffold Protein in the Regulation of Mitogen-Activated Protein Kinase Signaling Pathways

A tumor-associated splice-isoform of MAP2K7 drives dedifferentiation in MBNL1-low cancers via JNK activation

Anti-inflammatory Effects of Empagliflozin and Gemigliptin on LPS-Stimulated Macrophage via the IKK/NF-κB, MKK7/JNK, and JAK2/STAT1 Signalling Pathways

Mitogen Kinase Kinase (MKK7) Controls Cytokine Production In Vitro and In Vivo in Mice

Activation of c-Jun N-terminal kinase (JNK) by widely used specific p38 MAPK inhibitors SB202190 and SB203580: A MLK-3-MKK7-dependent mechanism

Loss of T Regulatory Cell Suppression following Signaling through Glucocorticoid-induced Tumor Necrosis Receptor (GITR) Is Dependent on c-Jun N-terminal Kinase Activation

MKK3 was involved in larval settlement of the barnacle Amphibalanus amphitrite through activating the kinase activity of p38MAPK

Lycorine suppresses RANKL-induced osteoclastogenesis in vitro and prevents ovariectomy-induced osteoporosis and titanium particle-induced osteolysis in vivo

Scaffold Role of DUSP22 in ASK1-MKK7-JNK Signaling Pathway

Novel and Expanded Roles for MAPK Signaling in Arabidopsis Stomatal Cell Fate Revealed by Cell Type-Specific Manipulations

Arrestin-3 scaffolding of the JNK3 cascade suggests a mechanism for signal amplification

Heme Oxygenase-1 Inhibits Neuronal Apoptosis in Spinal Cord Injury through Down-Regulation of Cdc42-MLK3-MKK7-JNK3 Axis

Tumor Progression Locus 2 in Hepatocytes Potentiates Both Liver and Systemic Metabolic Disorders in Mice

Gq-Induced Apoptosis is Mediated by AKT Inhibition That Leads to PKC-Induced JNK Activation

Calcium/Ask1/MKK7/JNK2/c-Src signalling cascade mediates disruption of intestinal epithelial tight junctions by dextran sulfate sodium

Downregulated Gene Expression Spectrum and Immune Responses Changed During the Disease Progression in Patients With COVID-19

Structure and dynamics of the MKK7–JNK signaling complex

Discovery of Turn-On Fluorescent Probes for Detecting PDEδ Protein in Living Cells and Tumor Slices

Manipulation of Mitogen-Activated Protein Kinase Kinase Signaling in the Arabidopsis Stomatal Lineage Reveals Motifs That Contribute to Protein Localization and Signaling Specificity

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