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Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral hypoxia-ischemia

Cell death and differentiation, 2007-04, Vol.14 (4), p.775-784

2007

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MG132 exerts anti-viral activity against HSV-1 by overcoming virus-mediated suppression of the ERK signaling pathway

Scientific reports, 2020-04, Vol.10 (1), p.6671, Article 6671

2020

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Redox Regulation of Pro-IL-1β Processing May Contribute to the Increased Severity of Serum-Induced Arthritis in NOX2-Deficient Mice

Antioxidants & redox signaling, 2015-10, Vol.23 (12), p.973

2015

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PS-341, a novel proteasome inhibitor, induces Bcl-2 phosphorylation and cleavage in association with G2-M phase arrest and apoptosis

Molecular cancer therapeutics, 2002-08, Vol.1 (10), p.841-849

2002

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Discovery of Ketone-Based Covalent Inhibitors of Coronavirus 3CL Proteases for the Potential Therapeutic Treatment of COVID-19

Journal of medicinal chemistry, 2020-11, Vol.63 (21), p.12725-12747

2020

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Effects of Porphyromonas gingivalis infection on human gingival epithelial barrier function in vitro

European journal of oral sciences, 2010-12, Vol.118 (6), p.582-589

2010

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Imidazole Ketone Erastin Induces Ferroptosis and Slows Tumor Growth in a Mouse Lymphoma Model

Cell chemical biology, 2019-05, Vol.26 (5), p.623-633.e9

2019

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Diketopyrrolopyrrole–Triphenylamine Organic Nanoparticles as Multifunctional Reagents for Photoacoustic Imaging-Guided Photodynamic/Photothermal Synergistic Tumor Therapy

ACS nano, 2017-01, Vol.11 (1), p.1054-1063

2017

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SGLT2 inhibition modulates NLRP3 inflammasome activity via ketones and insulin in diabetes with cardiovascular disease

Nature communications, 2020-05, Vol.11 (1), p.2127-2127, Article 2127

2020

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TNF antagonist sensitizes synovial fibroblasts to ferroptotic cell death in collagen-induced arthritis mouse models

Nature communications, 2022-02, Vol.13 (1), p.676-676, Article 676

2022

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Structure-Based Optimization of ML300-Derived, Noncovalent Inhibitors Targeting the Severe Acute Respiratory Syndrome Coronavirus 3CL Protease (SARS-CoV‑2 3CLpro)

Journal of medicinal chemistry, 2022-02, Vol.65 (4), p.2880-2904

2022

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Serine protease inhibitors interact with IFN-γ through up-regulation of FasR; a novel therapeutic strategy against cancer

Experimental cell research, 2015-01, Vol.330 (2), p.233-239

2015

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Radical aryl migration enables diversity-oriented synthesis of structurally diverse medium/macro- or bridged-rings

Nature communications, 2016-12, Vol.7 (1), p.13852-13852, Article 13852

2016

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3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV‑2 Agents

Journal of medicinal chemistry, 2022-02, Vol.65 (4), p.2926-2939

2022

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Furin Inhibitors Block SARS-CoV-2 Spike Protein Cleavage to Suppress Virus Production and Cytopathic Effects

Cell reports (Cambridge), 2020-10, Vol.33 (2), p.108254-108254, Article 108254

2020

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Activation of the CED3/ICE-Related Protease CPP32 in Cerebellar Granule Neurons Undergoing Apoptosis But Not Necrosis

The Journal of neuroscience, 1997-01, Vol.17 (2), p.553-562

1997

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Piperlongumine rapidly induces the death of human pancreatic cancer cells mainly through the induction of ferroptosis

International journal of oncology, 2018-03, Vol.52 (3), p.1011-1022

2018

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MXene-Based Hydrogels Endow Polyetheretherketone with Effective Osteogenicity and Combined Treatment of Osteosarcoma and Bacterial Infection

ACS applied materials & interfaces, 2020-10, Vol.12 (41), p.45891-45903

2020

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Recent advances in α,β-unsaturated carbonyl compounds as mitochondrial toxins

European journal of medicinal chemistry, 2019-12, Vol.183, p.111687, Article 111687

2019

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Anti-Microtubule Drugs

Methods in molecular biology (Clifton, N.J.), 2016, Vol.1413, p.403

2016

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Multiple caspases are involved in β-amyloid-induced neuronal apoptosis

Journal of neuroscience research, 2001-07, Vol.65 (1), p.45-53

2001

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1,4-Diselenophene-1,4-diketone Triggers Caspase-Dependent Apoptosis in Human Melanoma A375 Cells through Induction of Mitochondrial Dysfunction

Chemical and Pharmaceutical Bulletin, 2011/10/01, Vol.59(10), pp.1227-1232

2011

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Facile Surface Modification Method for Synergistically Enhancing the Biocompatibility and Bioactivity of Poly(ether ether ketone) That Induced Osteodifferentiation

ACS applied materials & interfaces, 2019-08, Vol.11 (31), p.27503-27511

2019

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Design, synthesis and inhibitory effect of pentapeptidyl chloromethyl ketones on proteinase K

Bioorganic & medicinal chemistry, 2010-12, Vol.18 (23), p.8383-8387

2010

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Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral hypoxia-ischemia

MG132 exerts anti-viral activity against HSV-1 by overcoming virus-mediated suppression of the ERK signaling pathway

Redox Regulation of Pro-IL-1β Processing May Contribute to the Increased Severity of Serum-Induced Arthritis in NOX2-Deficient Mice

PS-341, a novel proteasome inhibitor, induces Bcl-2 phosphorylation and cleavage in association with G2-M phase arrest and apoptosis

Discovery of Ketone-Based Covalent Inhibitors of Coronavirus 3CL Proteases for the Potential Therapeutic Treatment of COVID-19

Effects of Porphyromonas gingivalis infection on human gingival epithelial barrier function in vitro

Imidazole Ketone Erastin Induces Ferroptosis and Slows Tumor Growth in a Mouse Lymphoma Model

Diketopyrrolopyrrole–Triphenylamine Organic Nanoparticles as Multifunctional Reagents for Photoacoustic Imaging-Guided Photodynamic/Photothermal Synergistic Tumor Therapy

SGLT2 inhibition modulates NLRP3 inflammasome activity via ketones and insulin in diabetes with cardiovascular disease

TNF antagonist sensitizes synovial fibroblasts to ferroptotic cell death in collagen-induced arthritis mouse models

Peptidomimetic α‑Acyloxymethylketone Warheads with Six-Membered Lactam P1 Glutamine Mimic: SARS-CoV‑2 3CL Protease Inhibition, Coronavirus Antiviral Activity, and in Vitro Biological Stability

Structure-Based Optimization of ML300-Derived, Noncovalent Inhibitors Targeting the Severe Acute Respiratory Syndrome Coronavirus 3CL Protease (SARS-CoV‑2 3CLpro)

Serine protease inhibitors interact with IFN-γ through up-regulation of FasR; a novel therapeutic strategy against cancer

Radical aryl migration enables diversity-oriented synthesis of structurally diverse medium/macro- or bridged-rings

3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV‑2 Agents

Furin Inhibitors Block SARS-CoV-2 Spike Protein Cleavage to Suppress Virus Production and Cytopathic Effects

Activation of the CED3/ICE-Related Protease CPP32 in Cerebellar Granule Neurons Undergoing Apoptosis But Not Necrosis

Piperlongumine rapidly induces the death of human pancreatic cancer cells mainly through the induction of ferroptosis

MXene-Based Hydrogels Endow Polyetheretherketone with Effective Osteogenicity and Combined Treatment of Osteosarcoma and Bacterial Infection

Recent advances in α,β-unsaturated carbonyl compounds as mitochondrial toxins

Anti-Microtubule Drugs

Multiple caspases are involved in β-amyloid-induced neuronal apoptosis

1,4-Diselenophene-1,4-diketone Triggers Caspase-Dependent Apoptosis in Human Melanoma A375 Cells through Induction of Mitochondrial Dysfunction

Facile Surface Modification Method for Synergistically Enhancing the Biocompatibility and Bioactivity of Poly(ether ether ketone) That Induced Osteodifferentiation

Design, synthesis and inhibitory effect of pentapeptidyl chloromethyl ketones on proteinase K

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