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Interleukin-10 paradox: A potent immunoregulatory cytokine that has been difficult to harness for immunotherapy

Cytokine (Philadelphia, Pa.), 2015-07, Vol.74 (1), p.27-34

2015

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Interleukin-10: new perspectives on an old cytokine

Immunological reviews, 2008-12, Vol.226 (1), p.205-218

2008

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Targeting IL-10 Family Cytokines for the Treatment of Human Diseases

Cold Spring Harbor perspectives in biology, 2019-02, Vol.11 (2), p.a028548

2019

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Safety, Antitumor Activity, and Immune Activation of Pegylated Recombinant Human Interleukin-10 (AM0010) in Patients With Advanced Solid Tumors

Journal of clinical oncology, 2016-10, Vol.34 (29), p.3562-3569

2016

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The therapeutic potential of interleukin-10 in neuroimmune diseases

Neuropharmacology, 2015-09, Vol.96 (Pt A), p.55-69

2015

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Targeted Interleukin-10 Nanotherapeutics Developed with a Microfluidic Chip Enhance Resolution of Inflammation in Advanced Atherosclerosis

ACS nano, 2016-05, Vol.10 (5), p.5280-5292

2016

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Title: IL-10-producing T cells and their dual functions

Seminars in immunology, 2019-08, Vol.44, p.101335-101335

2019

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Current status of interleukin-10 and regulatory T-cells in cancer

Current opinion in oncology, 2013-11, Vol.25 (6), p.637-645

2013

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Why interleukin-10 supplementation does not work in Crohn's disease patients

World journal of gastroenterology : WJG, 2013-07, Vol.19 (25), p.3931-3941

2013

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Immune regulation and cytotoxic T cell activation of IL-10 agonists – Preclinical and clinical experience

Seminars in immunology, 2019-08, Vol.44, p.101325-101325, Article 101325

Oft, Martin

2019

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A1 astrocytes contribute to murine depression-like behavior and cognitive dysfunction, which can be alleviated by IL-10 or fluorocitrate treatment

Journal of neuroinflammation, 2020-07, Vol.17 (1), p.200-13, Article 200

2020

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Transplantation of mesenchymal stem cells genetically engineered to overexpress interleukin-10 promotes alternative inflammatory response in rat model of traumatic brain injury

Journal of neuroinflammation, 2019-01, Vol.16 (1), p.2-2, Article 2

2019

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Effects of spinal non-viral interleukin-10 gene therapy formulated with d-mannose in neuropathic interleukin-10 deficient mice: Behavioral characterization, mRNA and protein analysis in pain relevant tissues

Brain, behavior, and immunity, 2018-03, Vol.69, p.91-112

2018

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Inflammation in first‐episode psychosis: The contribution of inflammatory biomarkers to the emergence of negative symptoms, a systematic review and meta‐analysis

Acta psychiatrica Scandinavica, 2022-07, Vol.146 (1), p.6-20

2022

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Anti-inflammatory IL-10 administration rescues depression-associated learning and memory deficits in mice

Journal of neuroinflammation, 2020-08, Vol.17 (1), p.246-246, Article 246

2020

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Cytokines as potential combination agents with PD‐1/PD‐L1 blockade for cancer treatment

Journal of cellular physiology, 2020-07, Vol.235 (7-8), p.5449-5460

2020

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IL4-10 Fusion Protein Is a Novel Drug to Treat Persistent Inflammatory Pain

The Journal of neuroscience, 2016-07, Vol.36 (28), p.7353-7363

2016

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Interleukin-10 protects against atherosclerosis by modulating multiple atherogenic macrophage function

Thrombosis and haemostasis, 2015-05, Vol.113 (3), p.505

2015

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Cell specific delivery of modified mRNA expressing therapeutic proteins to leukocytes

Nature communications, 2018-10, Vol.9 (1), p.4493-9, Article 4493

2018

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Interleukin-10 improves stroke outcome by controlling the detrimental Interleukin-17A response

Journal of neuroinflammation, 2021-11, Vol.18 (1), p.265-265, Article 265

2021

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Interleukin-10 therapy--review of a new approach

Pharmacological reviews, 2003-06, Vol.55 (2), p.241

2003

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Interleukin-10 Inhibits Bone Resorption: A Potential Therapeutic Strategy in Periodontitis and Other Bone Loss Diseases

BioMed research international, 2014-01, Vol.2014, p.284836-5

2014

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Delivery of interleukin-10 via injectable hydrogels improves renal outcomes and reduces systemic inflammation following ischemic acute kidney injury in mice

American journal of physiology. Renal physiology, 2016-08, Vol.311 (2), p.F362-F372

2016

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Interleukin-10 Treatment Attenuates Pressure Overload―Induced Hypertrophic Remodeling and Improves Heart Function via Signal Transducers and Activators of Transcription 3―Dependent Inhibition of Nuclear Factor-κB

Circulation (New York, N.Y.), 2012-07, Vol.126 (4), p.418-429

2012

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Interleukin-10 paradox: A potent immunoregulatory cytokine that has been difficult to harness for immunotherapy

Interleukin-10: new perspectives on an old cytokine

Targeting IL-10 Family Cytokines for the Treatment of Human Diseases

Safety, Antitumor Activity, and Immune Activation of Pegylated Recombinant Human Interleukin-10 (AM0010) in Patients With Advanced Solid Tumors

PEGylated IL-10 (Pegilodecakin) Induces Systemic Immune Activation, CD8+ T Cell Invigoration and Polyclonal T Cell Expansion in Cancer Patients

The therapeutic potential of interleukin-10 in neuroimmune diseases

Targeted Interleukin-10 Nanotherapeutics Developed with a Microfluidic Chip Enhance Resolution of Inflammation in Advanced Atherosclerosis

Title: IL-10-producing T cells and their dual functions

Current status of interleukin-10 and regulatory T-cells in cancer

Why interleukin-10 supplementation does not work in Crohn's disease patients

Immune regulation and cytotoxic T cell activation of IL-10 agonists – Preclinical and clinical experience

A1 astrocytes contribute to murine depression-like behavior and cognitive dysfunction, which can be alleviated by IL-10 or fluorocitrate treatment

Transplantation of mesenchymal stem cells genetically engineered to overexpress interleukin-10 promotes alternative inflammatory response in rat model of traumatic brain injury

Effects of spinal non-viral interleukin-10 gene therapy formulated with d-mannose in neuropathic interleukin-10 deficient mice: Behavioral characterization, mRNA and protein analysis in pain relevant tissues

Inflammation in first‐episode psychosis: The contribution of inflammatory biomarkers to the emergence of negative symptoms, a systematic review and meta‐analysis

Anti-inflammatory IL-10 administration rescues depression-associated learning and memory deficits in mice

Cytokines as potential combination agents with PD‐1/PD‐L1 blockade for cancer treatment

IL4-10 Fusion Protein Is a Novel Drug to Treat Persistent Inflammatory Pain

Interleukin-10 protects against atherosclerosis by modulating multiple atherogenic macrophage function

Cell specific delivery of modified mRNA expressing therapeutic proteins to leukocytes

Interleukin-10 improves stroke outcome by controlling the detrimental Interleukin-17A response

Interleukin-10 therapy--review of a new approach

Interleukin-10 Inhibits Bone Resorption: A Potential Therapeutic Strategy in Periodontitis and Other Bone Loss Diseases

Delivery of interleukin-10 via injectable hydrogels improves renal outcomes and reduces systemic inflammation following ischemic acute kidney injury in mice

Interleukin-10 Treatment Attenuates Pressure Overload―Induced Hypertrophic Remodeling and Improves Heart Function via Signal Transducers and Activators of Transcription 3―Dependent Inhibition of Nuclear Factor-κB

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