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Direct inhibition of the DNA-binding activity of POU transcription factors Pit-1 and Brn-3 by selective binding of a phenyl-furan-benzimidazole dication

Nucleic acids research, 2008-06, Vol.36 (10), p.3341

2008

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Selective inhibition of anandamide cellular uptake versus enzymatic hydrolysis—a difficult issue to handle

European journal of pharmacology, 2004-05, Vol.492 (1), p.1-11

2004

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Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors

Cell death & disease, 2019-02, Vol.10 (2), p.128-128, Article 128

2019

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mTOR kinase structure, mechanism and regulation

Nature (London), 2013-05, Vol.497 (7448), p.217-223

2013

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Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L

Acta pharmacologica Sinica, 2018-05, Vol.39 (5), p.787-801

2018

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Crystal Structure of NLRP3 NACHT Domain With an Inhibitor Defines Mechanism of Inflammasome Inhibition

Journal of molecular biology, 2021-12, Vol.433 (24), p.167309-167309, Article 167309

2021

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Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice

Science translational medicine, 2018-10, Vol.10 (465)

2018

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Identification of Dihydrofuro[3,4‑d]pyrimidine Derivatives as Novel HIV‑1 Non-Nucleoside Reverse Transcriptase Inhibitors with Promising Antiviral Activities and Desirable Physicochemical Properties

Journal of medicinal chemistry, 2019-02, Vol.62 (3), p.1484-1501

2019

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Enhanced Cardiomyocyte NLRP3 Inflammasome Signaling Promotes Atrial Fibrillation

Circulation (New York, N.Y.), 2018-11, Vol.138 (20), p.2227-2242

2018

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NLRP3 inflammasome inhibition with MCC950 improves diabetes-mediated cognitive impairment and vasoneuronal remodeling after ischemia

Pharmacological research, 2019-04, Vol.142, p.237-250

2019

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Strigolactone and Karrikin Signaling Pathways Elicit Ubiquitination and Proteolysis of SMXL2 to Regulate Hypocotyl Elongation in Arabidopsis[OPEN]

The Plant cell, 2020-07, Vol.32 (7), p.2251-2270

2020

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Anti-Microtubule Drugs

Methods in molecular biology (Clifton, N.J.), 2016, Vol.1413, p.403

2016

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Bioresin-based superhydrophobic coatings with reduced bacterial adhesion

Journal of colloid and interface science, 2020-08, Vol.574, p.20-32

2020

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Novel Diamidino-Substituted Derivatives of Phenyl Benzothiazolyl and Dibenzothiazolyl Furans and Thiophenes: Synthesis, Antiproliferative and DNA Binding Properties

Journal of medicinal chemistry, 2010-03, Vol.53 (6), p.2418-2432

2010

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Curcumin-free turmeric exhibits anti-inflammatory and anticancer activities: Identification of novel components of turmeric

Molecular nutrition & food research, 2013-09, Vol.57 (9), p.1529-1542

2013

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Drugging the PI3 Kinome: From Chemical Tools to Drugs in the Clinic

Cancer research (Chicago, Ill.), 2010-03, Vol.70 (6), p.2146-2157

2010

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Syringaresinol attenuates sepsis-induced cardiac dysfunction by inhibiting inflammation and pyroptosis in mice

European journal of pharmacology, 2021-12, Vol.913, p.174644-174644, Article 174644

2021

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Development of Novel Dihydrofuro[3,4‑d]pyrimidine Derivatives as HIV‑1 NNRTIs to Overcome the Highly Resistant Mutant Strains F227L/V106A and K103N/Y181C

Journal of medicinal chemistry, 2022-02, Vol.65 (3), p.2458-2470

2022

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Design, synthesis, molecular docking and cytotoxic evaluation of novel 2-furybenzimidazoles as VEGFR-2 inhibitors

European journal of medicinal chemistry, 2017-08, Vol.136, p.315-329

2017

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A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat

Proceedings of the National Academy of Sciences - PNAS, 2007-05, Vol.104 (20), p.8520-8525

2007

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Tetramic and tetronic acids: An update on new derivatives and biological aspects

Bioorganic & medicinal chemistry, 2008-04, Vol.16 (8), p.4203-4221

2008

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Synthesis and evaluation of novel arctigenin derivatives as potential anti-Toxoplasma gondii agents

European journal of medicinal chemistry, 2018-10, Vol.158, p.414-427

2018

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Aureonitol Analogues and Orsellinic Acid Esters Isolated from Chaetomium elatum and Their Antineuroinflammatory Activity

Journal of natural products (Washington, D.C.), 2021-12, Vol.84 (12), p.3044-3054

2021

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The selective NLRP3 inhibitor MCC950 hinders atherosclerosis development by attenuating inflammation and pyroptosis in macrophages

Scientific reports, 2021-09, Vol.11 (1), p.19305-19305, Article 19305

2021

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Design, synthesis and bioactivity study on 5-phenylfuran derivatives as potent reversal agents against P-glycoprotein-mediated multidrug resistance in MCF-7/ADR cell

European journal of medicinal chemistry, 2021-04, Vol.216, p.113336-113336, Article 113336

2021

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Direct inhibition of the DNA-binding activity of POU transcription factors Pit-1 and Brn-3 by selective binding of a phenyl-furan-benzimidazole dication

Selective inhibition of anandamide cellular uptake versus enzymatic hydrolysis—a difficult issue to handle

Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors

mTOR kinase structure, mechanism and regulation

Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L

Crystal Structure of NLRP3 NACHT Domain With an Inhibitor Defines Mechanism of Inflammasome Inhibition

Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice

Identification of Dihydrofuro[3,4‑d]pyrimidine Derivatives as Novel HIV‑1 Non-Nucleoside Reverse Transcriptase Inhibitors with Promising Antiviral Activities and Desirable Physicochemical Properties

Enhanced Cardiomyocyte NLRP3 Inflammasome Signaling Promotes Atrial Fibrillation

NLRP3 inflammasome inhibition with MCC950 improves diabetes-mediated cognitive impairment and vasoneuronal remodeling after ischemia

Strigolactone and Karrikin Signaling Pathways Elicit Ubiquitination and Proteolysis of SMXL2 to Regulate Hypocotyl Elongation in Arabidopsis[OPEN]

Anti-Microtubule Drugs

Bioresin-based superhydrophobic coatings with reduced bacterial adhesion

Novel Diamidino-Substituted Derivatives of Phenyl Benzothiazolyl and Dibenzothiazolyl Furans and Thiophenes: Synthesis, Antiproliferative and DNA Binding Properties

Curcumin-free turmeric exhibits anti-inflammatory and anticancer activities: Identification of novel components of turmeric

Drugging the PI3 Kinome: From Chemical Tools to Drugs in the Clinic

Syringaresinol attenuates sepsis-induced cardiac dysfunction by inhibiting inflammation and pyroptosis in mice

Development of Novel Dihydrofuro[3,4‑d]pyrimidine Derivatives as HIV‑1 NNRTIs to Overcome the Highly Resistant Mutant Strains F227L/V106A and K103N/Y181C

Design, synthesis, molecular docking and cytotoxic evaluation of novel 2-furybenzimidazoles as VEGFR-2 inhibitors

A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat

Tetramic and tetronic acids: An update on new derivatives and biological aspects

Synthesis and evaluation of novel arctigenin derivatives as potential anti-Toxoplasma gondii agents

Aureonitol Analogues and Orsellinic Acid Esters Isolated from Chaetomium elatum and Their Antineuroinflammatory Activity

The selective NLRP3 inhibitor MCC950 hinders atherosclerosis development by attenuating inflammation and pyroptosis in macrophages

Design, synthesis and bioactivity study on 5-phenylfuran derivatives as potent reversal agents against P-glycoprotein-mediated multidrug resistance in MCF-7/ADR cell

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