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SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

Nature (London), 2011-03, Vol.471 (7336), p.104

2011

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Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly

Nature (London), 2021-02, Vol.590 (7847), p.671-676

2021

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SCF ubiquitin ligase-targeted therapies

Nature reviews. Drug discovery, 2014-12, Vol.13 (12), p.889-903

2014

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F-box protein TIR1 is an auxin receptor

Nature, 2005-05, Vol.435 (7041), p.441-445

2005

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SCF(TIR1/AFB)-auxin signalling regulates PIN vacuolar trafficking and auxin fluxes during root gravitropism

The EMBO journal, 2013-01, Vol.32 (2), p.260-274

2013

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Lipopolysaccharide Primes the NALP3 Inflammasome by Inhibiting Its Ubiquitination and Degradation Mediated by the SCFFBXL2 E3 Ligase

The Journal of biological chemistry, 2015-07, Vol.290 (29), p.18124-18133

2015

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SCFAtPP2-B11 modulates ABA signaling by facilitating SnRK2.3 degradation in Arabidopsis thaliana

PLoS genetics, 2017-08, Vol.13 (8), p.e1006947-e1006947

2017

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The Arabidopsis F-box protein TIR1 is an auxin receptor

Nature, 2005-05, Vol.435 (7041), p.446-451

2005

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Cand1 Promotes Assembly of New SCF Complexes through Dynamic Exchange of F Box Proteins

Cell, 2013-03, Vol.153 (1), p.206-215

2013

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FBXW7/hCDC4 is a general tumor suppressor in human cancer

Cancer research (Chicago, Ill.), 2007-10, Vol.67 (19), p.9006-9012

2007

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Systemwide disassembly and assembly of SCF ubiquitin ligase complexes

Cell, 2023-04, Vol.186 (9), p.1895-1911.e21

2023

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Control of Iron Homeostasis by an Iron-Regulated Ubiquitin Ligase

Science (American Association for the Advancement of Science), 2009-10, Vol.326 (5953), p.718-721

2009

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Auxin receptors and plant development: a new signaling paradigm

Annual review of cell and developmental biology, 2008-01, Vol.24 (1), p.55-80

2008

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FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B―cell lymphomas

Nature (London), 2012-01, Vol.481 (7379), p.90-93

2012

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Structure of a Fbw7-Skp1-Cyclin E Complex: Multisite-Phosphorylated Substrate Recognition by SCF Ubiquitin Ligases

Molecular cell, 2007-04, Vol.26 (1), p.131-143

2007

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The SCF ubiquitin ligase: insights into a molecular machine

Nature reviews. Molecular cell biology, 2004-09, Vol.5 (9), p.739-751

2004

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GhTULP34, a member of tubby-like proteins, interacts with GhSKP1A to negatively regulate plant osmotic stress

Genomics (San Diego, Calif.), 2021-01, Vol.113 (1), p.462-474

2021

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The Arabidopsis F-box protein CORONATINE INSENSITIVE1 is stabilized by SCFCOI1 and degraded via the 26S proteasome pathway

The Plant cell, 2013-02, Vol.25 (2), p.486-498

2013

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PKD1 Phosphorylation-Dependent Degradation of SNAIL by SCF-FBXO11 Regulates Epithelial-Mesenchymal Transition and Metastasis

Cancer cell, 2014-09, Vol.26 (3), p.358-373

2014

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Identification of an E3 ligase that targets the catalytic subunit of RNA Polymerase I upon transcription stress

The Journal of biological chemistry, 2022-12, Vol.298 (12), p.102690-102690, Article 102690

2022

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SCFFbxl³ Controls the Oscillation of the Circadian Clock by Directing the Degradation of Cryptochrome Proteins

Science (American Association for the Advancement of Science), 2007-05, Vol.316 (5826), p.900-904

2007

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Parallel SCF Adaptor Capture Proteomics Reveals a Role for SCFFBXL17 in NRF2 Activation via BACH1 Repressor Turnover

Molecular cell, 2013-10, Vol.52 (1), p.9-24

2013

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Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease

Biochemical journal, 2016-10, Vol.473 (20), p.3563-3580

2016

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F-box receptor mediated control of substrate stability and subcellular location organizes cellular development of Aspergillus nidulans

PLoS genetics, 2022-12, Vol.18 (12), p.e1010502-e1010502

2022

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Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complex

Molecular cell, 2006-11, Vol.24 (3), p.355-366

2006

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SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly

SCF ubiquitin ligase-targeted therapies

F-box protein TIR1 is an auxin receptor

SCF(TIR1/AFB)-auxin signalling regulates PIN vacuolar trafficking and auxin fluxes during root gravitropism

Lipopolysaccharide Primes the NALP3 Inflammasome by Inhibiting Its Ubiquitination and Degradation Mediated by the SCFFBXL2 E3 Ligase

SCFAtPP2-B11 modulates ABA signaling by facilitating SnRK2.3 degradation in Arabidopsis thaliana

The Arabidopsis F-box protein TIR1 is an auxin receptor

Cand1 Promotes Assembly of New SCF Complexes through Dynamic Exchange of F Box Proteins

FBXW7/hCDC4 is a general tumor suppressor in human cancer

Systemwide disassembly and assembly of SCF ubiquitin ligase complexes

Control of Iron Homeostasis by an Iron-Regulated Ubiquitin Ligase

Auxin receptors and plant development: a new signaling paradigm

FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B―cell lymphomas

Structure of a Fbw7-Skp1-Cyclin E Complex: Multisite-Phosphorylated Substrate Recognition by SCF Ubiquitin Ligases

The SCF ubiquitin ligase: insights into a molecular machine

GhTULP34, a member of tubby-like proteins, interacts with GhSKP1A to negatively regulate plant osmotic stress

The Arabidopsis F-box protein CORONATINE INSENSITIVE1 is stabilized by SCFCOI1 and degraded via the 26S proteasome pathway

PKD1 Phosphorylation-Dependent Degradation of SNAIL by SCF-FBXO11 Regulates Epithelial-Mesenchymal Transition and Metastasis

Identification of an E3 ligase that targets the catalytic subunit of RNA Polymerase I upon transcription stress

SCFFbxl³ Controls the Oscillation of the Circadian Clock by Directing the Degradation of Cryptochrome Proteins

Parallel SCF Adaptor Capture Proteomics Reveals a Role for SCFFBXL17 in NRF2 Activation via BACH1 Repressor Turnover

Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease

F-box receptor mediated control of substrate stability and subcellular location organizes cellular development of Aspergillus nidulans

Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complex

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