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The circRNA circSEPT9 mediated by E2F1 and EIF4A3 facilitates the carcinogenesis and development of triple-negative breast cancer

Molecular cancer, 2020-04, Vol.19 (1), p.73-22, Article 73

2020

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Cyclin F Controls Cell-Cycle Transcriptional Outputs by Directing the Degradation of the Three Activator E2Fs

Molecular cell, 2019-06, Vol.74 (6), p.1264-1277.e7

2019

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Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer

Nature medicine, 2016-04, Vol.22 (4), p.369-378

2016

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Long noncoding RNA LINC00511 contributes to breast cancer tumourigenesis and stemness by inducing the miR-185-3p/E2F1/Nanog axis

Journal of experimental & clinical cancer research, 2018-11, Vol.37 (1), p.289-289, Article 289

2018

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LncRNA SNHG3 is activated by E2F1 and promotes proliferation and migration of non‐small‐cell lung cancer cells through activating TGF‐β pathway and IL‐6/JAK2/STAT3 pathway

Journal of cellular physiology, 2020-03, Vol.235 (3), p.2891-2900

2020

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Profound Tissue Specificity in Proliferation Control Underlies Cancer Drivers and Aneuploidy Patterns

Cell, 2018-04, Vol.173 (2), p.499-514.e23

2018

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Bi-allelic Loss of CDKN2A Initiates Melanoma Invasion via BRN2 Activation

Cancer cell, 2018-07, Vol.34 (1), p.56-68.e9

2018

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EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop

Nature communications, 2017-10, Vol.8 (1), p.877-16, Article 877

2017

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circCAMSAP1 Promotes Tumor Growth in Colorectal Cancer via the miR-328-5p/E2F1 Axis

Molecular therapy, 2020-03, Vol.28 (3), p.914-928

2020

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The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway

Cell death and differentiation, 2017-02, Vol.24 (2), p.212-224

2017

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The E2F Transcription Factors Regulate Tumor Development and Metastasis in a Mouse Model of Metastatic Breast Cancer

Molecular and cellular biology, 2014-09, Vol.34 (17), p.3229-3243

2014

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RB localizes to DNA double-strand breaks and promotes DNA end resection and homologous recombination through the recruitment of BRG1

Genes & development, 2016-11, Vol.30 (22), p.2500-2512

2016

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Histone Variant H2A.Z.2 Mediates Proliferation and Drug Sensitivity of Malignant Melanoma

Molecular cell, 2015-07, Vol.59 (1), p.75-88

2015

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The oncofetal RNA-binding protein IGF2BP1 is a druggable, post-transcriptional super-enhancer of E2F-driven gene expression in cancer

Nucleic acids research, 2020-09, Vol.48 (15), p.8576

2020

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E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells

Nature (London), 2009-12, Vol.462 (7275), p.930-934

2009

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Long noncoding RNA DLX6-AS1 accelerates the glioma carcinogenesis by competing endogenous sponging miR-197-5p to relieve E2F1

Gene, 2019-02, Vol.686, p.1-7

2019

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POH1 deubiquitylates and stabilizes E2F1 to promote tumour formation

Nature communications, 2015-10, Vol.6 (1), p.8704-8704, Article 8704

2015

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Canonical and atypical E2Fs regulate the mammalian endocycle

Nature cell biology, 2012-11, Vol.14 (11), p.1192

2012

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Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma

The Journal of clinical investigation, 2017-03, Vol.127 (3), p.830-842

2017

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Long non-coding RNA HULC promotes tumor angiogenesis in liver cancer by up-regulating sphingosine kinase 1 (SPHK1)

Oncotarget, 2016-01, Vol.7 (1), p.241-254

2016

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E2F1 sumoylation as a protective cellular mechanism in oxidative stress response

Proceedings of the National Academy of Sciences - PNAS, 2020-06, Vol.117 (26), p.14958-14969

2020

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E2F1 Drives Breast Cancer Metastasis by Regulating the Target Gene FGF13 and Altering Cell Migration

Scientific reports, 2019-07, Vol.9 (1), p.10718-13, Article 10718

2019

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KLF4 is regulated by RAS/RAF/MEK/ERK signaling through E2F1 and promotes melanoma cell growth

Oncogene, 2017-06, Vol.36 (23), p.3322-3333

2017

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Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression

Nature (London), 2010-07, Vol.466 (7306), p.637-641

2010

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E2F1-EP300 co-activator complex potentiates immune escape in nasopharyngeal carcinoma through the mediation of MELK

Histology and histopathology, 2024-04, Vol.39 (4), p.511-523

2024

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The circRNA circSEPT9 mediated by E2F1 and EIF4A3 facilitates the carcinogenesis and development of triple-negative breast cancer

Cyclin F Controls Cell-Cycle Transcriptional Outputs by Directing the Degradation of the Three Activator E2Fs

Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer

Long noncoding RNA LINC00511 contributes to breast cancer tumourigenesis and stemness by inducing the miR-185-3p/E2F1/Nanog axis

LncRNA SNHG3 is activated by E2F1 and promotes proliferation and migration of non‐small‐cell lung cancer cells through activating TGF‐β pathway and IL‐6/JAK2/STAT3 pathway

Profound Tissue Specificity in Proliferation Control Underlies Cancer Drivers and Aneuploidy Patterns

Bi-allelic Loss of CDKN2A Initiates Melanoma Invasion via BRN2 Activation

EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop

circCAMSAP1 Promotes Tumor Growth in Colorectal Cancer via the miR-328-5p/E2F1 Axis

The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway

The E2F Transcription Factors Regulate Tumor Development and Metastasis in a Mouse Model of Metastatic Breast Cancer

RB localizes to DNA double-strand breaks and promotes DNA end resection and homologous recombination through the recruitment of BRG1

Histone Variant H2A.Z.2 Mediates Proliferation and Drug Sensitivity of Malignant Melanoma

The oncofetal RNA-binding protein IGF2BP1 is a druggable, post-transcriptional super-enhancer of E2F-driven gene expression in cancer

E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells

Long noncoding RNA DLX6-AS1 accelerates the glioma carcinogenesis by competing endogenous sponging miR-197-5p to relieve E2F1

POH1 deubiquitylates and stabilizes E2F1 to promote tumour formation

Canonical and atypical E2Fs regulate the mammalian endocycle

Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma

Long non-coding RNA HULC promotes tumor angiogenesis in liver cancer by up-regulating sphingosine kinase 1 (SPHK1)

E2F1 sumoylation as a protective cellular mechanism in oxidative stress response

E2F1 Drives Breast Cancer Metastasis by Regulating the Target Gene FGF13 and Altering Cell Migration

KLF4 is regulated by RAS/RAF/MEK/ERK signaling through E2F1 and promotes melanoma cell growth

Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression

E2F1-EP300 co-activator complex potentiates immune escape in nasopharyngeal carcinoma through the mediation of MELK

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