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T4 DNA ligase structure reveals a prototypical ATP-dependent ligase with a unique mode of sliding clamp interaction

Nucleic acids research, 2018-11, Vol.46 (19), p.10474

2018

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Catalytically inactive DNA ligase IV promotes DNA repair in living cells

Nucleic acids research, 2022-10, Vol.50 (19), p.11058

2022

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Horizontal acquisition of a DNA ligase improves DNA damage tolerance in eukaryotes

Nature communications, 2023-11, Vol.14 (1), p.7638-7638, Article 7638

2023

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Deficiency of ligase IV leads to reduced NHEJ, accumulation of DNA damage, and can sensitize cells to cancer therapeutics

Genomics (San Diego, Calif.), 2023-11, Vol.115 (6), p.110731-110731, Article 110731

2023

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Mammalian DNA ligases; roles in maintaining genome integrity

Journal of molecular biology, 2024-01, Vol.436 (1), p.168276-168276, Article 168276

2024

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Autoimmunity and immunodeficiency associated with monoallelic LIG4 mutations via haploinsufficiency

Journal of allergy and clinical immunology, 2023-08, Vol.152 (2), p.500-516

2023

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Dynamic DNA-bound PCNA complexes co-ordinate Okazaki fragment synthesis, processing and ligation

Journal of molecular biology, 2020-12, Vol.432 (24), p.166698-166698, Article 166698

2020

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A role for the ATP-dependent DNA ligase lig E of Neisseria gonorrhoeae in biofilm formation

BMC microbiology, 2024-01, Vol.24 (1), p.29-29, Article 29

2024

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Unchanged PCNA and DNMT1 dynamics during replication in DNA ligase I-deficient cells but abnormal chromatin levels of non-replicative histone H1

Scientific reports, 2023-03, Vol.13 (1), p.4363-4363, Article 4363

2023

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DNA ligase IV mutations confer shorter lifespan and increased sensitivity to nutrient stress in Drosophila melanogaster

Journal of applied genetics, 2022-02, Vol.63 (1), p.141-144

2022

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Hypomorphic mutations in human DNA ligase IV lead to compromised DNA binding efficiency, hydrophobicity and thermal stability

Protein engineering, design and selection, 2021-02, Vol.34

2021

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Single-Nucleotide Polymorphisms of Genes Involved in Repair of Oxidative DNA Damage and the Risk of Recurrent Depressive Disorder

Medical science monitor, 2016-11, Vol.22, p.4455-4474

2016

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Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining

Nature biotechnology, 2015-05, Vol.33 (5), p.538-542

2015

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Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells

Nature biotechnology, 2015-05, Vol.33 (5), p.543-548

2015

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Association between Single-Nucleotide Polymorphisms of the hOGG1,NEIL1,APEX1, FEN1,LIG1, and LIG3 Genes and Alzheimer's Disease Risk

Neuropsychobiology, 2016-01, Vol.73 (2), p.98-107

2016

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Two-Stage Synapsis of DNA Ends during Non-homologous End Joining

Molecular cell, 2016-03, Vol.61 (6), p.850-858

2016

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Single-stranded DNA library preparation from highly degraded DNA using T4 DNA ligase

Nucleic acids research, 2017-06, Vol.45 (10), p.e79

2017

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DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation

PLoS genetics, 2011-06, Vol.7 (6), p.e1002080

2011

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Chromosomal Translocations in Human Cells Are Generated by Canonical Nonhomologous End-Joining

Molecular cell, 2014-09, Vol.55 (6), p.829-842

2014

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An Inhibitor of Nonhomologous End-Joining Abrogates Double-Strand Break Repair and Impedes Cancer Progression

Cell, 2012-12, Vol.151 (7), p.1474-1487

2012

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A Mechanism to Minimize Errors during Non-homologous End Joining

Molecular cell, 2020-03, Vol.77 (5), p.1080-1091.e8

2020

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Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair

Nature (London), 2011-03, Vol.471 (7337), p.245-248

2011

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Biallelic Gene Targeting in Rice

Plant physiology (Bethesda), 2016-02, Vol.170 (2), p.667-677

2016

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Biosensor reveals multiple sources for mitochondrial NAD

Science (American Association for the Advancement of Science), 2016-06, Vol.352 (6292), p.1474-1477

2016

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Human DNA ligases I and IIIα as determinants of accuracy and efficiency of base excision DNA repair

Biochimie, 2024-04, Vol.219, p.84-95

2024

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T4 DNA ligase structure reveals a prototypical ATP-dependent ligase with a unique mode of sliding clamp interaction

Catalytically inactive DNA ligase IV promotes DNA repair in living cells

Horizontal acquisition of a DNA ligase improves DNA damage tolerance in eukaryotes

Deficiency of ligase IV leads to reduced NHEJ, accumulation of DNA damage, and can sensitize cells to cancer therapeutics

Mammalian DNA ligases; roles in maintaining genome integrity

Autoimmunity and immunodeficiency associated with monoallelic LIG4 mutations via haploinsufficiency

Dynamic DNA-bound PCNA complexes co-ordinate Okazaki fragment synthesis, processing and ligation

A role for the ATP-dependent DNA ligase lig E of Neisseria gonorrhoeae in biofilm formation

Unchanged PCNA and DNMT1 dynamics during replication in DNA ligase I-deficient cells but abnormal chromatin levels of non-replicative histone H1

DNA ligase IV mutations confer shorter lifespan and increased sensitivity to nutrient stress in Drosophila melanogaster

Hypomorphic mutations in human DNA ligase IV lead to compromised DNA binding efficiency, hydrophobicity and thermal stability

Single-Nucleotide Polymorphisms of Genes Involved in Repair of Oxidative DNA Damage and the Risk of Recurrent Depressive Disorder

Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining

Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells

Association between Single-Nucleotide Polymorphisms of the hOGG1,NEIL1,APEX1, FEN1,LIG1, and LIG3 Genes and Alzheimer's Disease Risk

Two-Stage Synapsis of DNA Ends during Non-homologous End Joining

Single-stranded DNA library preparation from highly degraded DNA using T4 DNA ligase

DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation

Chromosomal Translocations in Human Cells Are Generated by Canonical Nonhomologous End-Joining

An Inhibitor of Nonhomologous End-Joining Abrogates Double-Strand Break Repair and Impedes Cancer Progression

A Mechanism to Minimize Errors during Non-homologous End Joining

Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair

Biallelic Gene Targeting in Rice

Biosensor reveals multiple sources for mitochondrial NAD

Human DNA ligases I and IIIα as determinants of accuracy and efficiency of base excision DNA repair

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