UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist gegebenenfalls nur via VPN oder Shibboleth (DFN-AAI) möglich. mehr Informationen...

Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite

Drug metabolism and disposition, 2010-01, Vol.38 (1), p.92

2010

Link zum Volltext

Verfügbarkeit prüfen

Use of Human Plasma Samples to Identify Circulating Drug Metabolites that Inhibit Cytochrome P450 Enzymes

Drug metabolism and disposition, 2016-08, Vol.44 (8), p.1217-1228

2016

Link zum Volltext

Verfügbarkeit prüfen

Hepatic cytochrome P450 enzyme alterations in humans with progressive stages of nonalcoholic fatty liver disease

Drug metabolism and disposition, 2009-10, Vol.37 (10), p.2087

2009

Link zum Volltext

Verfügbarkeit prüfen

Drinking Ethanol Has Few Acute Effects on CYP2C9, CYP2C19, NAT2, and P‐Glycoprotein Activities but Somewhat Inhibits CYP1A2, CYP2D6, and Intestinal CYP3A: So What?

Clinical pharmacology and therapeutics, 2018-12, Vol.104 (6), p.1249-1259

2018

Link zum Volltext

Verfügbarkeit prüfen

The Potential for Pharmacokinetic Interactions Between Cannabis Products and Conventional Medications

Journal of clinical psychopharmacology, 2019-09, Vol.39 (5), p.462

2019

Link zum Volltext

Verfügbarkeit prüfen

Evaluation of Mutual Drug–Drug Interaction within Geneva Cocktail for Cytochrome P450 Phenotyping using Innovative Dried Blood Sampling Method

Basic & clinical pharmacology & toxicology, 2016-09, Vol.119 (3), p.284-290

2016

Link zum Volltext

Verfügbarkeit prüfen

A Highly Selective Ratiometric Two-Photon Fluorescent Probe for Human Cytochrome P450 1A

Journal of the American Chemical Society, 2015-11, Vol.137 (45), p.14488-14495

2015

Link zum Volltext

Verfügbarkeit prüfen

Differences in the Epigenetic Regulation of Cytochrome P450 Genes between Human Embryonic Stem Cell-Derived Hepatocytes and Primary Hepatocytes

PloS one, 2015-07, Vol.10 (7), p.e0132992

2015

Link zum Volltext

Verfügbarkeit prüfen

Physiologically based pharmacokinetic modeling to predict drug-drug interactions involving inhibitory metabolite: a case study of amiodarone

Drug metabolism and disposition, 2015-02, Vol.43 (2), p.182-189

2015

Link zum Volltext

Verfügbarkeit prüfen

Scaffold Hopping and Optimization of Maleimide Based Porcupine Inhibitors

Journal of medicinal chemistry, 2017-08, Vol.60 (15), p.6678-6692

2017

Link zum Volltext

Verfügbarkeit prüfen

Structure−Function Relationships of Inhibition of Human Cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 Flavonoid Derivatives

Chemical research in toxicology, 2010-12, Vol.23 (12), p.1921-1935

2010

Link zum Volltext

Verfügbarkeit prüfen

Induction of CYP1A1, CYP1A2, CYP1B1, increased oxidative stress and inflammation in the lung and liver tissues of rats exposed to incense smoke

Molecular and cellular biochemistry, 2014-06, Vol.391 (1-2), p.127-136

2014

Link zum Volltext

Verfügbarkeit prüfen

Impact of CYP1A2, CYP2C19, and CYP2D6 genotype- and phenoconversion-predicted enzyme activity on clozapine exposure and symptom severity

The pharmacogenomics journal, 2020-04, Vol.20 (2), p.192-201

2020

Link zum Volltext

Verfügbarkeit prüfen

Understanding a substrate's product regioselectivity in a family of enzymes: a case study of acetaminophen binding in cytochrome P450s

PloS one, 2014-02, Vol.9 (2), p.e87058-e87058

2014

Link zum Volltext

Verfügbarkeit prüfen

The inhibition of CYP1A2, CYP2C9, and CYP2D6 by pterostilbene in human liver microsomes

Pharmazie, 2021-04, Vol.76 (4), p.155-158

2021

Link zum Volltext

Verfügbarkeit prüfen

3D Spheroid Primary Human Hepatocytes for Prediction of Cytochrome P450 and Drug Transporter Induction

Clinical pharmacology and therapeutics, 2023-06, Vol.113 (6), p.1284-1294

2023

Link zum Volltext

Verfügbarkeit prüfen

Use of Phenoxyaniline Analogues To Generate Biochemical Insights into the Interactio n of Polybrominated Diphenyl Ether with CYP2B Enzymes

Biochemistry (Easton), 2018-02, Vol.57 (5), p.817-826

2018

Link zum Volltext

Verfügbarkeit prüfen

CYP450 Genotype/Phenotype Concordance in Mexican Amerindian Indigenous Populations-Where to from Here for Global Precision Medicine?

Omics (Larchmont, N.Y.), 2017-09, Vol.21 (9), p.509

2017

Link zum Volltext

Verfügbarkeit prüfen

CYP enzymes, expressed within live human suspension cells, are superior to widely-used microsomal enzymes in identifying potent CYP1A1/CYP1B1 inhibitors: Identification of quinazolinones as CYP1A1/CYP1B1 inhibitors that efficiently reverse B[a]P toxicity and cisplatin resistance

European journal of pharmaceutical sciences, 2019-04, Vol.131, p.177-194

2019

Link zum Volltext

Verfügbarkeit prüfen

Hydroxychloroquine is Metabolized by Cytochrome P450 2D6, 3A4, and 2C8, and Inhibits Cytochrome P450 2D6, while its Metabolites also Inhibit Cytochrome P450 3A in vitro

Drug metabolism and disposition, 2023-03, Vol.51 (3), p.293-305

2023

Link zum Volltext

Verfügbarkeit prüfen

Pogostone inhibits the activity of CYP3A4, 2C9, and 2E1 in vitro

Pharmaceutical biology, 2021-01, Vol.59 (1), p.530-534

2021

Link zum Volltext

Verfügbarkeit prüfen

Cytochrome P450 Structure, Function and Clinical Significance: A Review

Current drug targets, 2018-01, Vol.19 (1), p.38

2018

Link zum Volltext

Verfügbarkeit prüfen

Differential expression of cytochrome P450 enzymes in normal and tumor tissues from childhood rhabdomyosarcoma

PloS one, 2014-04, Vol.9 (4), p.e93261-e93261

2014

Link zum Volltext

Verfügbarkeit prüfen

Prediction of Cytochrome P450 Inhibition Using a Deep Learning Approach and Substructure Pattern Recognition

Journal of chemical information and modeling, 2024-04, Vol.64 (7), p.2528-2538

2024

Link zum Volltext

Verfügbarkeit prüfen

Dibenzyl trisulfide binds to and competitively inhibits the cytochrome P450 1A1 active site without impacting the expression of the aryl hydrocarbon receptor

Toxicology and applied pharmacology, 2021-05, Vol.419, p.115502-115502, Article 115502

2021

Link zum Volltext

Verfügbarkeit prüfen

1 – 25 von 74.379

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(68.365)
Mit Volltextzugriff
(58.718)

Publikationsform

5 weitere anzeigen...

Weniger anzeigen...

Sprache

Englisch
(71.572)
Japanisch
(1.368)
Russisch
(1.023)
Chinesisch
(631)
Deutsch
(292)
Französisch
(243)
Spanisch
(142)
Polnisch
(135)
Portugiesisch
(90)
Norwegisch
(43)
Italienisch
(29)
Ungarisch
(27)
Niederländisch
(25)
Dänisch
(22)
Tschechisch
(19)
Ukrainisch
(18)
Schwedisch
(17)
Bulgarisch
(14)
Finnisch
(9)
Koreanisch
(9)

15 weitere anzeigen...

Weniger anzeigen...

Erscheinungsjahr

n.n

Thema

Science & Technology
(59.929)
Life Sciences & Biomedicine
(57.250)
Humans
(38.049)
Animals
(36.068)
Male
(29.162)
Cytochrome P-450 Enzyme System - Metabolism
(27.894)
Biological And Medical Sciences
(23.653)
Pharmacology & Pharmacy
(22.778)
Female
(18.811)
Rats
(17.557)
Medical Sciences
(16.741)
Cytochrome P-450 Enzyme System - Genetics
(13.123)
Biochemistry & Molecular Biology
(12.238)
Toxicology
(11.475)
Cytochrome P450
(9.809)
Adult
(9.184)
Pharmacology. Drug Treatments
(9.033)
Microsomes, Liver - Enzymology
(8.989)
Cytochrome P-450
(8.371)
Middle Aged
(8.231)

15 weitere anzeigen...

Weniger anzeigen...

Kollektion

Ingenta
(32.823)
EZB Free E-Journals
(27.504)
Journals@Ovid Complete
(24.501)
Elsevier ScienceDirect Journals Complete
(18.344)
Elsevier Journal Backfiles on ScienceDirect (DFG Nationallizenzen)
(17.237)
NUS Single-Journal Subscriptions
(11.723)
IngentaConnect Journals
(10.670)
Wiley Online Library - AutoHoldings Journals
(10.047)
Wiley Online Library Full Collection 2018
(7.229)
SpringerLink Journals - AutoHoldings
(7.053)
SpringerLINK Contemporary (Konsortium Baden-Württemberg)
(4.833)
Oxford Journals Current Collection
(3.902)
Taylor & Francis Current Content Access
(3.322)
Taylor & Francis Journals Complete
(3.297)
Oxford Journals 2020 Medicine
(2.576)
JSTOR Complete Journals
(1.453)
Nature_系列刊
(1.379)
Nexis Uni
(1.235)
SpringerLink Series
(1.022)
SAGE Complete
(873)

15 weitere anzeigen...

Weniger anzeigen...

Zeitschrift / Serie

Drug Metabolism And Disposition
(2.779)
Biochemical Pharmacology
(1.764)
The Journal Of Biological Chemistry
(1.389)
Xenobiotica
(1.246)
Biochemical And Biophysical Research Communications
(1.187)
Archives Of Biochemistry And Biophysics
(1.083)
Clinical Pharmacology And Therapeutics
(1.002)
Plos One
(910)
Toxicology And Applied Pharmacology
(900)
British Journal Of Clinical Pharmacology
(763)

5 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

Menü

Weitere Dienste

Einstellungen

Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite

Use of Human Plasma Samples to Identify Circulating Drug Metabolites that Inhibit Cytochrome P450 Enzymes

Hepatic cytochrome P450 enzyme alterations in humans with progressive stages of nonalcoholic fatty liver disease

Drinking Ethanol Has Few Acute Effects on CYP2C9, CYP2C19, NAT2, and P‐Glycoprotein Activities but Somewhat Inhibits CYP1A2, CYP2D6, and Intestinal CYP3A: So What?

The Potential for Pharmacokinetic Interactions Between Cannabis Products and Conventional Medications

Evaluation of Mutual Drug–Drug Interaction within Geneva Cocktail for Cytochrome P450 Phenotyping using Innovative Dried Blood Sampling Method

A Highly Selective Ratiometric Two-Photon Fluorescent Probe for Human Cytochrome P450 1A

Differences in the Epigenetic Regulation of Cytochrome P450 Genes between Human Embryonic Stem Cell-Derived Hepatocytes and Primary Hepatocytes

Physiologically based pharmacokinetic modeling to predict drug-drug interactions involving inhibitory metabolite: a case study of amiodarone

Scaffold Hopping and Optimization of Maleimide Based Porcupine Inhibitors

Structure−Function Relationships of Inhibition of Human Cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 Flavonoid Derivatives

Induction of CYP1A1, CYP1A2, CYP1B1, increased oxidative stress and inflammation in the lung and liver tissues of rats exposed to incense smoke

Impact of CYP1A2, CYP2C19, and CYP2D6 genotype- and phenoconversion-predicted enzyme activity on clozapine exposure and symptom severity

Understanding a substrate's product regioselectivity in a family of enzymes: a case study of acetaminophen binding in cytochrome P450s

The inhibition of CYP1A2, CYP2C9, and CYP2D6 by pterostilbene in human liver microsomes

3D Spheroid Primary Human Hepatocytes for Prediction of Cytochrome P450 and Drug Transporter Induction

Use of Phenoxyaniline Analogues To Generate Biochemical Insights into the Interactio n of Polybrominated Diphenyl Ether with CYP2B Enzymes

CYP450 Genotype/Phenotype Concordance in Mexican Amerindian Indigenous Populations-Where to from Here for Global Precision Medicine?

CYP enzymes, expressed within live human suspension cells, are superior to widely-used microsomal enzymes in identifying potent CYP1A1/CYP1B1 inhibitors: Identification of quinazolinones as CYP1A1/CYP1B1 inhibitors that efficiently reverse B[a]P toxicity and cisplatin resistance

Hydroxychloroquine is Metabolized by Cytochrome P450 2D6, 3A4, and 2C8, and Inhibits Cytochrome P450 2D6, while its Metabolites also Inhibit Cytochrome P450 3A in vitro

Pogostone inhibits the activity of CYP3A4, 2C9, and 2E1 in vitro

Cytochrome P450 Structure, Function and Clinical Significance: A Review

Differential expression of cytochrome P450 enzymes in normal and tumor tissues from childhood rhabdomyosarcoma

Prediction of Cytochrome P450 Inhibition Using a Deep Learning Approach and Substructure Pattern Recognition

Dibenzyl trisulfide binds to and competitively inhibits the cytochrome P450 1A1 active site without impacting the expression of the aryl hydrocarbon receptor

Suchergebnisse filtern