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The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA

Nature (London), 2016-04, Vol.532 (7600), p.517-521

2016

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Structural Basis for the RNA-Guided Ribonuclease Activity of CRISPR-Cas13d

Cell, 2018-09, Vol.175 (1), p.212-223.e17

2018

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Target preference of Type III-A CRISPR-Cas complexes at the transcription bubble

Nature communications, 2019-07, Vol.10 (1), p.3001-13, Article 3001

2019

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Mechanistic Insights into the cis- and trans-Acting DNase Activities of Cas12a

Molecular cell, 2019-02, Vol.73 (3), p.589-600.e4

2019

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The Molecular Architecture for RNA-Guided RNA Cleavage by Cas13a

Cell, 2017-08, Vol.170 (4), p.714-726.e10

2017

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C2c1-sgRNA Complex Structure Reveals RNA-Guided DNA Cleavage Mechanism

Molecular cell, 2017-01, Vol.65 (2), p.310-322

2017

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Cas13d Is a Compact RNA-Targeting Type VI CRISPR Effector Positively Modulated by a WYL-Domain-Containing Accessory Protein

Molecular cell, 2018-04, Vol.70 (2), p.327-339.e5

2018

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Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a

Molecular cell, 2017-04, Vol.66 (2), p.221-233.e4

2017

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Improving CRISPR-Cas specificity with chemical modifications in single-guide RNAs

Nucleic acids research, 2018-01, Vol.46 (2), p.792

2018

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Molecular Mechanisms of RNA Targeting by Cas13-containing Type VI CRISPR–Cas Systems

Journal of molecular biology, 2019-01, Vol.431 (1), p.66-87

O'Connell, Mitchell R.

2019

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Structure of the miniature type V-F CRISPR-Cas effector enzyme

Molecular cell, 2021-02, Vol.81 (3), p.558-570.e3

2021

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Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of Angptl3

Proceedings of the National Academy of Sciences - PNAS, 2021-03, Vol.118 (10), p.1

2021

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CRISPR-Based Technologies: Impact of RNA-Targeting Systems

Molecular cell, 2018-11, Vol.72 (3), p.404-412

Terns, Michael P

2018

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Self-Assembled DNA Nanoclews for the Efficient Delivery of CRISPR-Cas9 for Genome Editing

Angewandte Chemie (International ed.), 2015-10, Vol.54 (41), p.12029-12033

International ed. in English, 2015

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Cryo-EM structure of the transposon-associated TnpB enzyme

Nature (London), 2023-04, Vol.616 (7956), p.390-397

2023

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Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems

Molecular cell, 2017-03, Vol.65 (6), p.1109-1121.e3

2017

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The next generation of CRISPR-Cas technologies and applications

Nature reviews. Molecular cell biology, 2019-08, Vol.20 (8), p.490

2019

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CRISPR-Cas9 Structures and Mechanisms

Annual review of biophysics, 2017-05, Vol.46, p.505

2017

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Refined sgRNA efficacy prediction improves large- and small-scale CRISPR-Cas9 applications

Nucleic acids research, 2018-02, Vol.46 (3), p.1375

2018

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Programmable RNA recognition and cleavage by CRISPR/Cas9

Nature (London), 2014-12, Vol.516 (7530), p.263-266

2014

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Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1

Molecular cell, 2017-08, Vol.67 (4), p.633-645.e3

2017

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Crystal structure of the anti‐CRISPR, AcrIIC4

Protein science, 2021-12, Vol.30 (12), p.2474-2481

2021

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Aptazyme-embedded guide RNAs enable ligand-responsive genome editing and transcriptional activation

Nature communications, 2017-06, Vol.8 (1), p.15939-15939, Article 15939

2017

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RNA-guided DNA insertion with CRISPR-associated transposases

Science (American Association for the Advancement of Science), 2019-07, Vol.365 (6448), p.48-53

2019

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Guide RNA Functional Modules Direct Cas9 Activity and Orthogonality

Molecular cell, 2014-10, Vol.56 (2), p.333-339

2014

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The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA

Structural Basis for the RNA-Guided Ribonuclease Activity of CRISPR-Cas13d

Target preference of Type III-A CRISPR-Cas complexes at the transcription bubble

Mechanistic Insights into the cis- and trans-Acting DNase Activities of Cas12a

The Molecular Architecture for RNA-Guided RNA Cleavage by Cas13a

C2c1-sgRNA Complex Structure Reveals RNA-Guided DNA Cleavage Mechanism

Cas13d Is a Compact RNA-Targeting Type VI CRISPR Effector Positively Modulated by a WYL-Domain-Containing Accessory Protein

Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a

Improving CRISPR-Cas specificity with chemical modifications in single-guide RNAs

Molecular Mechanisms of RNA Targeting by Cas13-containing Type VI CRISPR–Cas Systems

Structure of the miniature type V-F CRISPR-Cas effector enzyme

Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of Angptl3

CRISPR-Based Technologies: Impact of RNA-Targeting Systems

Self-Assembled DNA Nanoclews for the Efficient Delivery of CRISPR-Cas9 for Genome Editing

Cryo-EM structure of the transposon-associated TnpB enzyme

Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems

The next generation of CRISPR-Cas technologies and applications

CRISPR-Cas9 Structures and Mechanisms

Refined sgRNA efficacy prediction improves large- and small-scale CRISPR-Cas9 applications

Programmable RNA recognition and cleavage by CRISPR/Cas9

Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1

Crystal structure of the anti‐CRISPR, AcrIIC4

Aptazyme-embedded guide RNAs enable ligand-responsive genome editing and transcriptional activation

RNA-guided DNA insertion with CRISPR-associated transposases

Guide RNA Functional Modules Direct Cas9 Activity and Orthogonality

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