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High-level semi-synthetic production of the potent antimalarial artemisinin

Nature (London), 2013-04, Vol.496 (7446), p.528-532

2013

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Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion

Science (American Association for the Advancement of Science), 2017-10, Vol.358 (6362), p.518-522

2017

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Ferrocene-Based Compounds with Antimalaria/Anticancer Activity

Molecules (Basel, Switzerland), 2019-10, Vol.24 (19), p.3604

2019

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Recent advances in malaria drug discovery

Bioorganic & medicinal chemistry letters, 2013-05, Vol.23 (10), p.2829-2843

2013

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A novel multiple-stage antimalarial agent that inhibits protein synthesis

Nature (London), 2015-06, Vol.522 (7556), p.315-320

2015

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Quinoline hybrids and their antiplasmodial and antimalarial activities

European journal of medicinal chemistry, 2017-10, Vol.139, p.22-47

2017

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Diversity-oriented synthesis yields novel multistage antimalarial inhibitors

Nature (London), 2016-10, Vol.538 (7625), p.344-349

2016

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Thousands of chemical starting points for antimalarial lead identification

Nature (London), 2010-05, Vol.465 (7296), p.305-310

2010

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Spiroindolone KAE609 for Falciparum and Vivax Malaria

The New England journal of medicine, 2014-07, Vol.371 (5), p.403-410

2014

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Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria

Proceedings of the National Academy of Sciences - PNAS, 2011-03, Vol.108 (11), p.4400-4405

2011

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A review on diverse heterocyclic compounds as the privileged scaffolds in antimalarial drug discovery

European journal of medicinal chemistry, 2018-10, Vol.158, p.917-936

2018

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Antimalarial Activity of KAF156 in Falciparum and Vivax Malaria

The New England journal of medicine, 2016-09, Vol.375 (12), p.1152-1160

2016

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Antimalarials from nature

Bioorganic & medicinal chemistry, 2009-05, Vol.17 (9), p.3229-3256

2009

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Quinoline-based antimalarial hybrid compounds

Bioorganic & medicinal chemistry, 2015-08, Vol.23 (16), p.5098-5119

2015

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Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria

Angewandte Chemie (International ed.), 2019-09, Vol.58 (37), p.13066-13079

International ed. in English, 2019

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Synthesis, biological evaluation and molecular docking of novel chalcone–coumarin hybrids as anticancer and antimalarial agents

European journal of medicinal chemistry, 2014-10, Vol.85, p.65-76

2014

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DSM265 at 400 Milligrams Clears Asexual Stage Parasites but Not Mature Gametocytes from the Blood of Healthy Subjects Experimentally Infected with Plasmodium falciparum

Antimicrobial agents and chemotherapy, 2019-04, Vol.63 (4)

2019

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Spiroindolones, a Potent Compound Class for the Treatment of Malaria

Science (American Association for the Advancement of Science), 2010-09, Vol.329 (5996), p.1175-1180

2010

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Semi-synthetic artemisinin: a model for the use of synthetic biology in pharmaceutical development

Nature reviews. Microbiology, 2014-05, Vol.12 (5), p.355-367

2014

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A Click Chemistry-Based Proteomic Approach Reveals that 1,2,4-Trioxolane and Artemisinin Antimalarials Share a Common Protein Alkylation Profile

Angewandte Chemie (International ed.), 2016-05, Vol.55 (22), p.6401-6405

International ed. in English, 2016

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Qinghaosu (Artemisinin): The Price of Success

Science (American Association for the Advancement of Science), 2008-04, Vol.320 (5874), p.330-334

White, N.J

2008

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Nonclassical Phenyl Bioisosteres as Effective Replacements in a Series of Novel Open-Source Antimalarials

Journal of medicinal chemistry, 2020-10, Vol.63 (20), p.11585-11601

2020

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The discovery of artemisinin (qinghaosu) and gifts from Chinese medicine

Nature medicine, 2011-10, Vol.17 (10), p.1217-1220

Tu, Youyou

2011

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Relationship between Antimalarial Activity and Heme Alkylation for Spiro- and Dispiro-1,2,4-Trioxolane Antimalarials

Antimicrobial Agents and Chemotherapy, 2008-04, Vol.52 (4), p.1291-1296

2008

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High-level semi-synthetic production of the potent antimalarial artemisinin

Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion

Ferrocene-Based Compounds with Antimalaria/Anticancer Activity

Recent advances in malaria drug discovery

A Monoclonal Antibody for Malaria Prevention

A novel multiple-stage antimalarial agent that inhibits protein synthesis

Quinoline hybrids and their antiplasmodial and antimalarial activities

Diversity-oriented synthesis yields novel multistage antimalarial inhibitors

Thousands of chemical starting points for antimalarial lead identification

Spiroindolone KAE609 for Falciparum and Vivax Malaria

Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria

A review on diverse heterocyclic compounds as the privileged scaffolds in antimalarial drug discovery

Antimalarial Activity of KAF156 in Falciparum and Vivax Malaria

Antimalarials from nature

Quinoline-based antimalarial hybrid compounds

Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria

Synthesis, biological evaluation and molecular docking of novel chalcone–coumarin hybrids as anticancer and antimalarial agents

DSM265 at 400 Milligrams Clears Asexual Stage Parasites but Not Mature Gametocytes from the Blood of Healthy Subjects Experimentally Infected with Plasmodium falciparum

Spiroindolones, a Potent Compound Class for the Treatment of Malaria

Semi-synthetic artemisinin: a model for the use of synthetic biology in pharmaceutical development

A Click Chemistry-Based Proteomic Approach Reveals that 1,2,4-Trioxolane and Artemisinin Antimalarials Share a Common Protein Alkylation Profile

Qinghaosu (Artemisinin): The Price of Success

Nonclassical Phenyl Bioisosteres as Effective Replacements in a Series of Novel Open-Source Antimalarials

The discovery of artemisinin (qinghaosu) and gifts from Chinese medicine

Relationship between Antimalarial Activity and Heme Alkylation for Spiro- and Dispiro-1,2,4-Trioxolane Antimalarials

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