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COPD as an endothelial disorder: endothelial injury linking lesions in the lungs and other organs? (2017 Grover Conference Series)

Pulmonary Circulation, 2018-01, Vol.8 (1), p.1-18

2018

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Loss of ADAM15 Exacerbates Transition to Decompensated Myocardial Hypertrophy and Dilation Through Activation of the Calcineurin Pathway

Hypertension (Dallas, Tex. 1979), 2023-01, Vol.80 (1), p.97-110

2023

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RNA-sequencing across three matched tissues reveals shared and tissue-specific gene expression and pathway signatures of COPD

Respiratory research, 2019-04, Vol.20 (1), p.65-65, Article 65

2019

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Inflammation in COPD: Implications for Management

The American journal of medicine, 2012-12, Vol.125 (12), p.1162-1170

2012

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CFTR regulates B cell activation and lymphoid follicle development

Respiratory research, 2019-07, Vol.20 (1), p.133-133, Article 133

2019

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Plasma metabolomics and clinical predictors of survival differences in COPD patients

Respiratory research, 2019-10, Vol.20 (1), p.219-219, Article 219

2019

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Rapid Lung Function Decline in Smokers Is a Risk Factor for COPD and Is Attenuated by Angiotensin-Converting Enzyme Inhibitor Use

Chest, 2014-04, Vol.145 (4), p.695-703

2014

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The Sulfate Groups of Chondroitin Sulfate- and Heparan Sulfate-containing Proteoglycans in Neutrophil Plasma Membranes Are Novel Binding Sites for Human Leukocyte Elastase and Cathepsin G

The Journal of biological chemistry, 2007-05, Vol.282 (19), p.14645-14654

2007

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ADAM15 expression is increased in lung CD8+ T cells, macrophages, and bronchial epithelial cells in patients with COPD and is inversely related to airflow obstruction

Respiratory research, 2020-07, Vol.21 (1), p.1-188, Article 188

2020

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Matrix metalloproteinases as therapeutic targets for idiopathic pulmonary fibrosis

American journal of respiratory cell and molecular biology, 2015-11, Vol.53 (5), p.585-600

2015

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A Disintegrin and Metalloproteinase 9 Domain (ADAM9) Is a Major Susceptibility Factor in the Early Stages of Encephalomyocarditis Virus Infection

mBio, 2019-02, Vol.10 (1)

2019

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Mononuclear phagocytes and airway epithelial cells: novel sources of matrix metalloproteinase-8 (MMP-8) in patients with idiopathic pulmonary fibrosis

PloS one, 2014-05, Vol.9 (5), p.e97485-e97485

2014

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Asthma COPD Overlap Syndrome: An Approach to A Real -World Endotype in Obstructive Lung Disease?

Current pharmaceutical design, 2016-01, Vol.22 (41), p.6273

2016

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Metabolomic profiling in a Hedgehog Interacting Protein (Hhip) murine model of chronic obstructive pulmonary disease

Scientific reports, 2017-05, Vol.7 (1), p.2504-13, Article 2504

2017

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Surface‐bound matrix metalloproteinase‐8 on macrophages: Contributions to macrophage pericellular proteolysis and migration through tissue barriers

Physiological reports, 2021-03, Vol.9 (5), p.e14778-n/a

2021

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CC16 augmentation reduces exaggerated COPD-like disease in Cc16-deficient mice

JCI insight, 2023-03, Vol.8 (6)

2023

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Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD

The Journal of clinical investigation, 2014-09, Vol.124 (9), p.3987-4003

2014

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Club cell protein 16 (Cc16) deficiency increases inflamm‐aging in the lungs of mice

Physiological reports, 2018-08, Vol.6 (15), p.e13797-n/a

2018

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Lung-Function Trajectories Leading to Chronic Obstructive Pulmonary Disease

The New England journal of medicine, 2015-07, Vol.373 (2), p.111-122

2015

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Dysregulation of miR-103a Mediates Cigarette Smoking-induced Lipid-laden Macrophage Formation

American journal of respiratory cell and molecular biology, 2022-12, Vol.67 (6), p.695-707

2022

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Extracellular vesicle-encapsulated CC16 as novel nanotherapeutics for treatment of acute lung injury

Molecular therapy, 2023-05, Vol.31 (5), p.1346-1364

2023

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Tissue Inhibitor of Metalloproteinase-1 Promotes Polymorphonuclear Neutrophil (PMN) Pericellular Proteolysis by Anchoring Matrix Metalloproteinase-8 and -9 to PMN Surfaces

The Journal of immunology (1950), 2019-06, Vol.202 (11), p.3267-3281

2019

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Endothelial Cell Death in Emphysema: More Sugarcoating Needed?

American journal of respiratory and critical care medicine, 2019-11, Vol.200 (9), p.1078-1080

2019

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Association of clonal hematopoiesis with chronic obstructive pulmonary disease

Blood, 2022-01, Vol.139 (3), p.357-368

2022

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B cells in chronic obstructive pulmonary disease: moving to center stage

American journal of physiology. Lung cellular and molecular physiology, 2016-10, Vol.311 (4), p.L687-L695

2016

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COPD as an endothelial disorder: endothelial injury linking lesions in the lungs and other organs? (2017 Grover Conference Series)

Loss of ADAM15 Exacerbates Transition to Decompensated Myocardial Hypertrophy and Dilation Through Activation of the Calcineurin Pathway

RNA-sequencing across three matched tissues reveals shared and tissue-specific gene expression and pathway signatures of COPD

Inflammation in COPD: Implications for Management

CFTR regulates B cell activation and lymphoid follicle development

Plasma metabolomics and clinical predictors of survival differences in COPD patients

Rapid Lung Function Decline in Smokers Is a Risk Factor for COPD and Is Attenuated by Angiotensin-Converting Enzyme Inhibitor Use

The Sulfate Groups of Chondroitin Sulfate- and Heparan Sulfate-containing Proteoglycans in Neutrophil Plasma Membranes Are Novel Binding Sites for Human Leukocyte Elastase and Cathepsin G

ADAM15 expression is increased in lung CD8+ T cells, macrophages, and bronchial epithelial cells in patients with COPD and is inversely related to airflow obstruction

Matrix metalloproteinases as therapeutic targets for idiopathic pulmonary fibrosis

A Disintegrin and Metalloproteinase 9 Domain (ADAM9) Is a Major Susceptibility Factor in the Early Stages of Encephalomyocarditis Virus Infection

Mononuclear phagocytes and airway epithelial cells: novel sources of matrix metalloproteinase-8 (MMP-8) in patients with idiopathic pulmonary fibrosis

Asthma COPD Overlap Syndrome: An Approach to A Real -World Endotype in Obstructive Lung Disease?

Metabolomic profiling in a Hedgehog Interacting Protein (Hhip) murine model of chronic obstructive pulmonary disease

Surface‐bound matrix metalloproteinase‐8 on macrophages: Contributions to macrophage pericellular proteolysis and migration through tissue barriers

CC16 augmentation reduces exaggerated COPD-like disease in Cc16-deficient mice

Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD

Club cell protein 16 (Cc16) deficiency increases inflamm‐aging in the lungs of mice

Lung-Function Trajectories Leading to Chronic Obstructive Pulmonary Disease

Dysregulation of miR-103a Mediates Cigarette Smoking-induced Lipid-laden Macrophage Formation

Extracellular vesicle-encapsulated CC16 as novel nanotherapeutics for treatment of acute lung injury

Tissue Inhibitor of Metalloproteinase-1 Promotes Polymorphonuclear Neutrophil (PMN) Pericellular Proteolysis by Anchoring Matrix Metalloproteinase-8 and -9 to PMN Surfaces

Endothelial Cell Death in Emphysema: More Sugarcoating Needed?

Association of clonal hematopoiesis with chronic obstructive pulmonary disease

B cells in chronic obstructive pulmonary disease: moving to center stage

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