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Cryo-EM structures capture the transport cycle of the P4-ATPase flippase

Science (American Association for the Advancement of Science), 2019-09, Vol.365 (6458), p.1149-1155

2019

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Cyclic GMP-AMP as an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA

Annual review of biochemistry, 2017-06, Vol.86, p.541

2017

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Molecular mechanisms of building blocks of life towards medicinal applications

The Keio Journal of Medicine, 2022, Vol.71(1), pp.32-32

Nureki, Osamu

2022

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Structures and mechanisms of CRISPR RNA-guided effector nucleases

Current opinion in structural biology, 2017-04, Vol.43, p.68-78

2017

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Structural biology of the multidrug and toxic compound extrusion superfamily transporters

Biochimica et biophysica acta. Biomembranes, 2020-12, Vol.1862 (12), p.183154, Article 183154

2020

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Taste transduction and channel synapses in taste buds

Pflügers Archiv, 2021-01, Vol.473 (1), p.3-13

2021

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Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9

Molecular cell, 2016-03, Vol.61 (6), p.886-894

2016

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Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1

Molecular cell, 2017-08, Vol.67 (4), p.633-645.e3

2017

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Structural insights into tetraspanin CD9 function

Nature communications, 2020-03, Vol.11 (1), p.1606-1606, Article 1606

2020

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Engineered CRISPR-Cas9 nuclease with expanded targeting space

Science (American Association for the Advancement of Science), 2018-09, Vol.361 (6408), p.1259-1262

2018

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The structure of lipid nanodisc-reconstituted TRPV3 reveals the gating mechanism

Nature structural & molecular biology, 2020-07, Vol.27 (7), p.645

2020

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TMC1 and TMC2 Proteins Are Pore-Forming Subunits of Mechanosensitive Ion Channels

Neuron (Cambridge, Mass.), 2020-01, Vol.105 (2), p.310-321.e3

2020

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Crystal structures of human ETB receptor provide mechanistic insight into receptor activation and partial activation

Nature communications, 2018-11, Vol.9 (1), p.1-11, Article 4711

2018

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Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1

Nature communications, 2018-10, Vol.9 (1), p.4424-8, Article 4424

2018

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Genome-wide CRISPR screen identifies TMEM41B as a gene required for autophagosome formation

The Journal of cell biology, 2018-11, Vol.217 (11), p.3817-3828

2018

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Recent Advances in the Structural Biology of the Volume-Regulated Anion Channel LRRC8

Frontiers in pharmacology, 2022-05, Vol.13, p.896532-896532

2022

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Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1

Molecular cell, 2017-07, Vol.67 (1), p.139-147.e2

2017

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Base editors for simultaneous introduction of C-to-T and A-to-G mutations

Nature biotechnology, 2020-07, Vol.38 (7), p.865-869

2020

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Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein

Nature structural & molecular biology, 2020-03, Vol.27 (3), p.274

2020

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Structure of the miniature type V-F CRISPR-Cas effector enzyme

Molecular cell, 2021-02, Vol.81 (3), p.558-570.e3

2021

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A three-dimensional movie of structural changes in bacteriorhodopsin

Science (American Association for the Advancement of Science), 2016-12, Vol.354 (6319), p.1552-1557

2016

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Activation mechanism of endothelin ETB receptor by endothelin-1

Nature (London), 2016-09, Vol.537 (7620), p.363-368

2016

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Amplification-free RNA detection with CRISPR-Cas13

Communications biology, 2021-04, Vol.4 (1), p.476-476, Article 476

2021

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Real-space and real-time dynamics of CRISPR-Cas9 visualized by high-speed atomic force microscopy

Nature communications, 2017-11, Vol.8 (1), p.1430-9, Article 1430

2017

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Structure and Engineering of Francisella novicida Cas9

Cell, 2016-02, Vol.164 (5), p.950-961

2016

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Cryo-EM structures capture the transport cycle of the P4-ATPase flippase

Cyclic GMP-AMP as an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA

Molecular mechanisms of building blocks of life towards medicinal applications

Structures and mechanisms of CRISPR RNA-guided effector nucleases

Structural biology of the multidrug and toxic compound extrusion superfamily transporters

Taste transduction and channel synapses in taste buds

Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9

Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1

Structural insights into tetraspanin CD9 function

Engineered CRISPR-Cas9 nuclease with expanded targeting space

The structure of lipid nanodisc-reconstituted TRPV3 reveals the gating mechanism

TMC1 and TMC2 Proteins Are Pore-Forming Subunits of Mechanosensitive Ion Channels

Crystal structures of human ETB receptor provide mechanistic insight into receptor activation and partial activation

Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1

Genome-wide CRISPR screen identifies TMEM41B as a gene required for autophagosome formation

Recent Advances in the Structural Biology of the Volume-Regulated Anion Channel LRRC8

Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1

Base editors for simultaneous introduction of C-to-T and A-to-G mutations

Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein

Structure of the miniature type V-F CRISPR-Cas effector enzyme

A three-dimensional movie of structural changes in bacteriorhodopsin

Activation mechanism of endothelin ETB receptor by endothelin-1

Amplification-free RNA detection with CRISPR-Cas13

Real-space and real-time dynamics of CRISPR-Cas9 visualized by high-speed atomic force microscopy

Structure and Engineering of Francisella novicida Cas9

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