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Matriptase activates stromelysin (MMP‐3) and promotes tumor growth and angiogenesis

Cancer science, 2006-12, Vol.97 (12), p.1327-1334

2006

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A Novel Biomarker for Staging Human Prostate Adenocarcinoma: Overexpression of Matriptase with Concomitant Loss of its Inhibitor, Hepatocyte Growth Factor Activator Inhibitor-1

Cancer epidemiology, biomarkers & prevention, 2006-02, Vol.15 (2), p.217-227

2006

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The Activation of Matriptase Requires Its Noncatalytic Domains, Serine Protease Domain, and Its Cognate Inhibitor

The Journal of biological chemistry, 2003-07, Vol.278 (29), p.26773-26779

2003

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Calmodulin-mediated Activation of Akt Regulates Survival of c-Myc-overexpressing Mouse Mammary Carcinoma Cells

The Journal of biological chemistry, 2004-09, Vol.279 (37), p.38903-38911

2004

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HAI-1 regulates activation and expression of matriptase, a membrane-bound serine protease

American Journal of Physiology: Cell Physiology, 2005-08, Vol.289 (2), p.C462-C470

2005

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Matriptase and HAI-1 Are Expressed by Normal and Malignant Epithelial Cells in Vitro and in Vivo

The American journal of pathology, 2001-04, Vol.158 (4), p.1301-1311

2001

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Autoactivation of matriptase in vitro: requirement for biomembrane and LDL receptor domain

American Journal of Physiology: Cell Physiology, 2007-07, Vol.293 (1), p.C95-C105

2007

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Characterization of Matriptase Expression in Normal Human Tissues

The journal of histochemistry and cytochemistry, 2003-08, Vol.51 (8), p.1017-1025

2003

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Roles of androgens in the development, growth, and carcinogenesis of the mammary gland

The Journal of steroid biochemistry and molecular biology, 2002-02, Vol.80 (2), p.175-189

2002

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Pentameric procyanidin from Theobroma cacao selectively inhibits growth of human breast cancer cells

Molecular cancer therapeutics, 2005-04, Vol.4 (4), p.537-546

2005

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Prognostic relevance of c-MYC gene amplification and polysomy for chromosome 8 in suboptimally-resected, advanced stage epithelial ovarian cancers: A Gynecologic Oncology Group study

Gynecologic oncology, 2009-09, Vol.114 (3), p.472-479

2009

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Type II transmembrane serine proteases

Thrombosis and haemostasis, 2003-08, Vol.90 (2), p.185

2003

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Simultaneous activation and hepatocyte growth factor activator inhibitor 1-mediated inhibition of matriptase induced at activation foci in human mammary epithelial cells

American Journal of Physiology: Cell Physiology, 2005-04, Vol.288 (4), p.C932-C941

2005

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Inhibition of Tumor Invasion by Genomic Down-regulation of Matriptase through Suppression of Activation of Receptor-bound Pro-urokinase

The Journal of biological chemistry, 2004-04, Vol.279 (15), p.14899-14908

2004

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Indole‐3‐carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells

International journal of cancer, 2006-02, Vol.118 (4), p.857-868

2006

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Sphingosine 1-Phosphate, Present in Serum-derived Lipoproteins, Activates Matriptase

The Journal of biological chemistry, 2002-03, Vol.277 (12), p.10539-10546

2002

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Identification of membrane‐bound serine proteinase matriptase as processing enzyme of insulin‐like growth factor binding protein‐related protein‐1 (IGFBP‐rP1/angiomodulin/mac25)

The FEBS journal, 2006-02, Vol.273 (3), p.615-627

2006

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Coexpression of β1,6-N-Acetylglucosaminyltransferase V Glycoprotein Substrates Defines Aggressive Breast Cancers with Poor Outcome

Cancer epidemiology, biomarkers & prevention, 2005-11, Vol.14 (11), p.2517-2523

2005

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Structure-Based Approach for the Discovery of Bis-benzamidines as Novel Inhibitors of Matriptase

Journal of medicinal chemistry, 2001-04, Vol.44 (9), p.1349-1355

2001

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Of mice and Myc: c-Myc and mammary tumorigenesis

Journal of mammary gland biology and neoplasia, 2004-01, Vol.9 (1), p.27-37

2004

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Co-expression of matriptase and N-acetylglucosaminyltransferase V in thyroid cancer tissues--its possible role in prolonged stability in vivo by aberrant glycosylation

Glycobiology (Oxford), 2006-05, Vol.16 (5), p.368-374

2006

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Activation of Hepatocyte Growth Factor and Urokinase/Plasminogen Activator by Matriptase, an Epithelial Membrane Serine Protease

The Journal of biological chemistry, 2000-11, Vol.275 (47), p.36720-36725

2000

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Production of soluble matriptase by human cancer cell lines and cell surface activation of its zymogen by trypsin

Journal of cellular biochemistry, 2005-06, Vol.95 (3), p.632-647

2005

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Tissue microarray analysis of hepatocyte growth factor/Met pathway components reveals a role for Met, matriptase, and hepatocyte growth factor activator inhibitor 1 in the progression of node-negative breast cancer

Cancer research (Chicago, Ill.), 2003-03, Vol.63 (5), p.1101-1105

2003

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A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

Matriptase activates stromelysin (MMP‐3) and promotes tumor growth and angiogenesis

A Novel Biomarker for Staging Human Prostate Adenocarcinoma: Overexpression of Matriptase with Concomitant Loss of its Inhibitor, Hepatocyte Growth Factor Activator Inhibitor-1

The Activation of Matriptase Requires Its Noncatalytic Domains, Serine Protease Domain, and Its Cognate Inhibitor

Calmodulin-mediated Activation of Akt Regulates Survival of c-Myc-overexpressing Mouse Mammary Carcinoma Cells

HAI-1 regulates activation and expression of matriptase, a membrane-bound serine protease

Matriptase and HAI-1 Are Expressed by Normal and Malignant Epithelial Cells in Vitro and in Vivo

Autoactivation of matriptase in vitro: requirement for biomembrane and LDL receptor domain

Characterization of Matriptase Expression in Normal Human Tissues

Roles of androgens in the development, growth, and carcinogenesis of the mammary gland

Pentameric procyanidin from Theobroma cacao selectively inhibits growth of human breast cancer cells

Prognostic relevance of c-MYC gene amplification and polysomy for chromosome 8 in suboptimally-resected, advanced stage epithelial ovarian cancers: A Gynecologic Oncology Group study

Type II transmembrane serine proteases

Simultaneous activation and hepatocyte growth factor activator inhibitor 1-mediated inhibition of matriptase induced at activation foci in human mammary epithelial cells

Inhibition of Tumor Invasion by Genomic Down-regulation of Matriptase through Suppression of Activation of Receptor-bound Pro-urokinase

Indole‐3‐carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells

Sphingosine 1-Phosphate, Present in Serum-derived Lipoproteins, Activates Matriptase

Identification of membrane‐bound serine proteinase matriptase as processing enzyme of insulin‐like growth factor binding protein‐related protein‐1 (IGFBP‐rP1/angiomodulin/mac25)

Coexpression of β1,6-N-Acetylglucosaminyltransferase V Glycoprotein Substrates Defines Aggressive Breast Cancers with Poor Outcome

Structure-Based Approach for the Discovery of Bis-benzamidines as Novel Inhibitors of Matriptase

Of mice and Myc: c-Myc and mammary tumorigenesis

Co-expression of matriptase and N-acetylglucosaminyltransferase V in thyroid cancer tissues--its possible role in prolonged stability in vivo by aberrant glycosylation

Activation of Hepatocyte Growth Factor and Urokinase/Plasminogen Activator by Matriptase, an Epithelial Membrane Serine Protease

Production of soluble matriptase by human cancer cell lines and cell surface activation of its zymogen by trypsin

Tissue microarray analysis of hepatocyte growth factor/Met pathway components reveals a role for Met, matriptase, and hepatocyte growth factor activator inhibitor 1 in the progression of node-negative breast cancer

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